Significance of free radical oxidation in purulent process development in patients with chronic generalized periodontitis I-II severity degree.

Авторы

  • I. I. Dronik

DOI:

https://doi.org/10.26641/2307-0404.2014.4.35808

Ключевые слова:

generalized periodontitis, lipid peroxidation

Аннотация

The results of the comparative study and the importance of free radical oxidation in causing purulent process in 46 patients with chronic generalized periodontitis I-II severity degree are presented. The aim - to study the characteristics of lipid peroxidation and antioxidant system in patients with generalized periodontitis, to establish the role of antiradical protection changes in suppurative inflammation in periodontal tissues. We found a substantial reduction of activity of key enzymes of antioxidant systems - superoxide dismutase and catalase in patients with chronic generalized periodontitis with suppuration of periodontal pockets, as compared with the rate in patients with septic foci in periodontal structures. It was stablished that lipid peroxidation is important in the development of purulent inflammation in periodontal tissues in patients with chronic generalized periodontitis, as evidenced by the significantly large accumulation of MDA and hydrate lipids in plasma and especially in the cellular elements of the blood (red blood cells) than in patients without this complication.

Биография автора

I. I. Dronik

SE "Bukovinian state medical university", department of therapeutic dentistry
Theatre Sq., 2, Chernivtsi, 58002, Ukraine

Библиографические ссылки

Кравченко Е.В., Кравченко Д.С. Ронолейкин в комплексном лечении заболеваний пародонта / Е.В. Крав¬ченко, Д.С. Кравченко // Фундаментальные исследования. – 2012. – № 7, ч. 2. – C. 355-358.

Лакин Г.Ф. Биометрия: учеб. пособие для биол. спец. вузов / Г.Ф.Лакин. – 4-е изд., перераб. и доп. – М.: Высшая школа, 1990. – 352 с.

Леус П.А. Значение некоторых индексов в эпиде¬миологических исследованиях болезней паро¬донта / П.А. Леус // Стоматология. – 1990. – Т. 69, № 1. – С. 80-83.

Мащенко И.С. Иммуногенетические аспекты ге¬не¬рализованного пародонтита / И.С. Мащенко, И.И. Со¬ко¬лова // Соврем. стоматология. - 2003. - № 4. - С. 44-46.

Мюллер Ханс-Питер. Пародонтология / Ханс-Питер Мюллер. – Львов: ГалДент, 2004. – 256 с.

Cochran D.L. Inflammation and bone loss in pe¬rio¬dontal disease / D.L. Cochran // J. Periodontol. – 2008. – Vol. 79. – P. 1569-1576.

Michael P.M. Immunological and Inflammatory Aspects of Periodontal Disease / P.M. Michael // Conti¬nuing Education Course. – 2013. – P. 1-18.

REFERENCES

Kravchenko E, Kravchenko D. [Ronoleukin in the complex treatment of periodontal disease]. Basic research. 2012;7:355-8. Russian.

Lakin GF. [Biometrics: 4th ed.]. Moscow. Vy¬shaya shkola. 1990;352. Russian.

Leus PA. [The value of some indices in epide¬mio¬logical studies of periodontal diseases]. J. Dentistry. 1990;69:80-83. Russian.

Mashchenko I, Sokolova II. [Immunologic as-¬

pects of generalized periodontitis]. Modern dentistry. 2003;4:44-46. Russian.

Muller HP. [Periodontics]. GalDent. 2004;256. Russian.

Cochran DL. Inflammation and bone loss in pe¬riodontal disease. J Periodontol. 2008;79:1569-76.

Michael PM. Immunological and Inflammatory As¬pects of Periodontal Disease. Continuing Education Course. 2013;1-18.

Загрузки

Опубликован

2014-11-24

Как цитировать

1.
Dronik II. Significance of free radical oxidation in purulent process development in patients with chronic generalized periodontitis I-II severity degree. Med. perspekt. [Интернет]. 24 ноябрь 2014 г. [цитируется по 19 декабрь 2024 г.];19(4):127-30. доступно на: https://journals.uran.ua/index.php/2307-0404/article/view/35808

Выпуск

Том 19 № 4 (2014)

Раздел

CLINICAL MEDICINE

Лицензия

Copyright (c) 2017 Medical Perspectives

Лицензия Creative Commons

Это произведение доступно по лицензии Creative Commons «Attribution-NonCommercial» («Атрибуция — Некоммерческое использование») 4.0 Всемирная.

Submitting manuscript to the journal "Medicni perspektivi" the author(s) agree with transferring copyright from the author(s) to publisher (including photos, figures, tables, etc.) editor, reproducing materials of the manuscript in the journal, Internet, translation into other languages, export and import of the issue with the author’s article, spreading without limitation of their period of validity both on the territory of Ukraine and other countries. This and other mutual duties of the author and all co-authors separately and editorial board are secured by written agreement by special form to use the article, the sample of which is presented on the site.

Author signs a written agreement and sends it to Editorial Board simultaneously with submission of the manuscript.