Neurotropic action of soy lecithin in the process of cognitive function formation in white rats.

Авторы

  • A. L. Drozdov
  • А. G. Rodinsky
  • А. G. Zubkovskaya
  • Е. М. Demchenko
  • L. A. Romanenko

DOI:

https://doi.org/10.26641/2307-0404.2015.1.40230

Ключевые слова:

soy lecithin, polyunsaturated fatty acids (PUFAs), cognitive function

Аннотация

In experiments conducted on white rats neurotropic action of soy lecithin, known as a source of unsaturated fatty acids on the background of the neurotoxic impact of CCl4was studied. Useage of CCl4by courses showed a significant inhibitory effect that affected the spontaneous behavior of rats “in the open field” by significant inhibition of mobility (44 - 77%), research activity (81%) and increased emotionality (140%). Suchusageofsoy lecithin having anti-oxidant activity and membrane-stabilizing effect led to optimization of spontaneous behavior of rats. Theinfringement of cognitive function is, possibly, due to the prooxydative effect ofCCl4 anddecreaseintheunsaturated fatty acid fraction in the structure of the brain lipids.Level of research, mink instinct, emotionality, vertical mobility were restored, and horizontal mobility even increased by 59%. Thus, soy lecithin may be recommended as a drug with correcting cognitive brain function.

Биографии авторов

A. L. Drozdov

SE «Dnipropetrovsk medical academy of Health Ministry of Ukraine»
Department of physiology
Dzerzhinsky str., 9, Dnipropetrovsk, 49044, Ukraine

А. G. Rodinsky

SE «Dnipropetrovsk medical academy of Health Ministry of Ukraine»
Department of physiology
Dzerzhinsky str., 9, Dnipropetrovsk, 49044, Ukraine

А. G. Zubkovskaya

SE «Dnipropetrovsk medical academy of Health Ministry of Ukraine»
Department of physiology
Dzerzhinsky str., 9, Dnipropetrovsk, 49044, Ukraine

Е. М. Demchenko

SE «Dnipropetrovsk medical academy of Health Ministry of Ukraine»
Department of physiology
Dzerzhinsky str., 9, Dnipropetrovsk, 49044, Ukraine

L. A. Romanenko

SE «Dnipropetrovsk medical academy of Health Ministry of Ukraine»
Department of physiology
Dzerzhinsky str., 9, Dnipropetrovsk, 49044, Ukraine

Библиографические ссылки

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Загрузки

Опубликован

2015-03-16

Как цитировать

1.
Drozdov AL, Rodinsky АG, Zubkovskaya АG, Demchenko ЕМ, Romanenko LA. Neurotropic action of soy lecithin in the process of cognitive function formation in white rats. Med. perspekt. [Интернет]. 16 март 2015 г. [цитируется по 24 ноябрь 2024 г.];20(1):4-9. доступно на: https://journals.uran.ua/index.php/2307-0404/article/view/40230

Выпуск

Раздел

THEORETICAL MEDICINE