Complex estimation of functional changes in the organism of healthy rats which consumed water of the lake Kagul as drinking water.
DOI:
https://doi.org/10.26641/2307-0404.2015.2.45680Ключевые слова:
water, lake Kagul, a chemical compound, anthropogenous pollutants, cyanobacteriaе, biological effects, ratsАннотация
In the work results of a complex estimation of functional changes in an organism of healthy rats which consumed water of the lake of Kagul as drinking water are given. Conformity of water of the lake of Kagul to requirements of operating standard documents except for nitrogen ammonia, nitrogen nitrit and the general organic carbon is established. 3 kinds of cyanobacteriaе, in particular high levels of Aphanocapsa pulverea, which causes water "flowering" are revealed. It is shown that the use of water of the lake of Kagul as drinking, causes strengthening of activity of central nervous system in healthy rats; some increase of possibilities of organism sensitisation development and specific phagocytosis, certain displays of disbalance of hummoral component of the immune response and expansion of autoimmune processes in the organism. In the view of absence of hyginicaly significant concentration of anthropogenous pollutants, the idea that the revealed biological effects are a consequence of cyanotoxins action produced by revealed cyanobacteriaе is presented. Necessity of expansion and continuation of researches on cyanobacteriaе in the context of their revealing in water, their identifications, influences of these xenobiotics on condition of warm-blooded animals and the human is proved.
Библиографические ссылки
Glants S. [Medical and biologic statistics. Trans. from English Ju.A. Danilov, under the editor of N.E. Bu¬zi¬ka¬shvili and D.V. Samolova]. М: practice, 1999;459. Russian. 2. [Sources of the Centralized Drinking Water Supply. Hygienic and Ecological Requirements as to the Quality of Water and the Rules for Its Samplings: State Standards 4808-2007].Кiev: Sttae Standard of Ukraine, 2007;36. Ukrainian. 3. Kovalchuk LI, Mokienko AV. [hygienic an estimation of eutrophication Ukrainian Danube region superficial reservoirs]. Actual problems of modern medicine: the Bulletin of the Ukrainian medical sto¬matologic academy. 2014;14(4,48):73-78. Ukrainian. 4. Kovalchuk LI, Mokienko AV, Nesterova DA. [Hygienic estimation of cyanobacteria of Ukrainian Da¬nube region lakes]. Biology and medicine achievements. 2014;2:10-14. Russian. 5. [Methodical recommendations about methods of researches of biological action of natural medical means and preforms means: mineral natural medical-table and medicinal waters, drinks on their basis; artificial-mine¬ralization waters; muds, brines, clay, waxs and prepa¬rations on their basis: Confirmed by the order of Ministry of Health of Ukraine from 28.09.2009 N 692]. Kiev, 2009;117. Ukrainian. 6. [The Order of the Ministry of education and science, youth and sports of Ukraine from 01.03.2012 N 249. The Official bulletin of Ukraine from 06.04.2012. - N 24]. 2012;82:942. Ukrainian. 7. Alexeenko NO, Pavlova OS, Nasibullin BA, Ru¬ch¬kina AS. [textbook on methods of researches of biolo¬gical action of natural medical means and preform means: mineral natural medical-table and medicinal waters, drinks on their basis; artificial-mineralization waters; muds, brines, clay, waxs and preparations on their basis]. Part 3. Odesa: UnesCo-Socio, 2002;114. Ukrainian. 8. Radchenko IG, Kapkov VI, Fedorov VD. [Prac¬tical guidance on gathering and the analysis of tests of a sea phytoplankton. The studies-methodical textbook for students of biological specialities of universities].М: Mordvincev, 2010;60. Russian. 9. [Sanitary Rules and Norms of the Superficial Waters Protection from Pollution. Sanitary Rules and Norms N 4630 – 88]. Moscow: Мinistry of Healt Care Of the USSR, 1988;69. Russian. 10. Directive 2010/63/ EU of the European Par¬liament and of the Council of 22 September 2010 on the protection of animals used for scientific purposes (Text with EEA relevance). Official Journal L 276, 20.10.2010:0033-0079. 11. El-Shehawy R, Gorokhova E, Fernández-Piñas F, del Campo FF. Global warming and hepatotoxin pro¬duction by cyanobacteria: What can we learn from experiments? Water Research. 2012;46(5):1420-9. 12. Guidelines for drinking water quality. The 4nd ed. Recommenda¬tions. World Health Organisation. Geneva. 2011;1:541. 13. van Apeldoorn ME, van Egmond HP, Speijers GJA, [et al.] Toxins of cyanobacteria. Review. Mol. Nutr. Food Res. 2007;51:7-60.
Загрузки
Опубликован
Как цитировать
Выпуск
Раздел
Лицензия
Copyright (c) 2017 Medical Perspectives
Это произведение доступно по лицензии Creative Commons «Attribution-NonCommercial» («Атрибуция — Некоммерческое использование») 4.0 Всемирная.
Submitting manuscript to the journal "Medicni perspektivi" the author(s) agree with transferring copyright from the author(s) to publisher (including photos, figures, tables, etc.) editor, reproducing materials of the manuscript in the journal, Internet, translation into other languages, export and import of the issue with the author’s article, spreading without limitation of their period of validity both on the territory of Ukraine and other countries. This and other mutual duties of the author and all co-authors separately and editorial board are secured by written agreement by special form to use the article, the sample of which is presented on the site.
Author signs a written agreement and sends it to Editorial Board simultaneously with submission of the manuscript.
