Experience of endovascular treatment of occlusion-stenotic lesions of cerebral arteries.

Авторы

  • Yu. V. Cherednichenko

DOI:

https://doi.org/10.26641/2307-0404.2016.1.63475

Ключевые слова:

cerebral arteries, occlusion and stenotic lesion, endovascular methods

Аннотация

Objective — to evaluate the efficacy of endovascular techniques in the treatment of occlusion and stenotic lesions of the brachiocephalic and cerebral arteries, to define the ways of complications prevention. Materials and methods. 594 patients with occlusion and stenotic lesions of the brachiocephalic and cerebral arteries were operated by endovascular methods in endovascular center of DnipropetrovskRegionalClinicalHospitalnamed after I.I. Mechnikov. 688 endovascular operations were carried out. Most part of the operations are carotid stenting (423 operations). All of these operations were carried out with the usage of different types of antiembolic protection systems: distal, proximal or their combination. Intracranial segments of cerebral arteries were operated in 43 cases. 169 operations of stenting of vertebral arteries in extracranial segments were performed. Subclavian arteries and brachiocephal truncus were operated in 53 cases. Results. Total removal of stenosis was achieved in 588 cases (98.99%). 509 patients (85.69% of cases) had improvement in neurological status (on a scale NIHHS, Mrs., MoCA). 77 (12.96%) patients had no deterioration of neurological status. Postoperative mortality was 1.01%. Common level of other complications was 4.3 %:  cerebral complications - 2.7%. Discussion. The results of the endovascular treatment of occlusion and stenotic lesions of the cerebral arteries show high efficacy and low complication level. The ways of reduction complications level are identified. They are in a differentiated selection of antiembolic protection method, endovascular treatment planning, based on monitoring of changes in the brain hemoperfusion, the emphasis is on the use of the special neurologic deviсes. Conclusions. Endovascular treatment of occlusion and stenotic lesions of the cerebral arteries is effective with a small risk of complications. Risk can be reduced further by the differential choice of antiembolic protection methods, with the help of wide use of special cerebral balloon-catheters and stents for the treatment of stenotic pathology of intracranial arteries, by planning stages of endovascular treatment, based on the clinical data, data of cerebral hemoperfusion in various areas of the brain, and cerebral angiography.

Биография автора

Yu. V. Cherednichenko

Dnipropetrovsk Regional Clinical Hospital named after I.I. Mechnikov
Sobornaya Sq., 14, Dnepropetrovsk, 49005, Ukraine

Библиографические ссылки

Voloshin PV, Misthenko TS, Lekomtseva EV. [Analysis of prevalence and incidence of neurological diseases in Ukraine]. Mezhdunarodnyij Nevrologicheskij Zhurnal. 2006;3(7):9–13. Ukrainian. 2. Misthenko TS. [Epidemiology of neurological diseases in Ukraine]. Neuro News. 2008;3:76–77. Ukrainian. 3. Barnett HJ, Taylor DW, Eliasziw M. Benefit of carotid endarterectomy in patients with symptomatic moderate or severe stenosis. North American Sympto-matic Carotid Endarterectomy Trial Collaborators. N. Engl. J. Med. 1998;339:1415-25. 4. European Carotid Surgery Trialists Collaborative Group. MRC European Carotid Surgery trial: interim results for symptomatic patients with severe (70-99%) or with mild (0-29%) carotid stenosis. Lancet. 1991;337:1235-43. 5. Executive Committee for the Asymptomatic Carotid Atherosclerosis Study. Endarterectomy for asymptomatic carotid artery stenosis. JAMA. 1995;273:1421-28. 6. MRC European Carotid Surgery Trialists. Randomised trial of endarterectomy for recently sympto-matic carotid stenosis: final results of the MRC European Carotid Surgery Trial (ECST). Lancet. 1998;351:1379-87. 7. North American Symptomatic Carotid Endar-terectomy Trial Collaborators. Beneficial effect of carotid endarterectomy in symptomatic patients with high-grade carotid stenosis. N. Engl. J. Med. 1991;325:445-53. 8. Stabile E, Salemme L, Sorropago G. Proximal endovascular occlusion for carotid artery stenting: Results from a prospective registry of 1,300 patients. J. Am. Coll. Cardiol. 2010;55:1661-67. 9. Gurm HS, Yadav JS, Fayad P. SAPPHIRE Investigators. Long-term results of carotid stenting versus endarterectomy in high-risk patients. N. Engl. J. Med. 2008;358:1572-9. 10. Yadav JS, Wholey MH, Kuntz RE. Stenting and Angioplasty with Protection in Patients at High Risk for Endarterectomy Investigators. Protected carotid-artery stenting versus endarterectomy in high-risk patients. N. Engl. J. Med. 2004;351:1493-501. 11. Brott TG, Hobson RW II, Howard G. Stenting versus endarterectomy for treatment of carotid-artery stenosis. N. Engl. J. Med. 2010;363(1):11-23. 12. Nasreddine ZS, Phillips NA, Bedirian V. The Mon-treal Cognitive Assessment (MoCA): A Brief Screening Tool For Mild Cognitive Impairment. Journal of the American Geriatrics Society. 2005;53:695-9.

Загрузки

Опубликован

2016-03-09

Как цитировать

1.
Cherednichenko YV. Experience of endovascular treatment of occlusion-stenotic lesions of cerebral arteries. Med. perspekt. [Интернет]. 9 март 2016 г. [цитируется по 23 ноябрь 2024 г.];21(1):52-63. доступно на: https://journals.uran.ua/index.php/2307-0404/article/view/63475

Выпуск

Раздел

CLINICAL MEDICINE