Clinical, microbiological, immunological and metabolic features of purulent process occurrence in the periodontium in patients with chronic generalized periodontitis.

Авторы

  • А. А. Gudaryan
  • N. B. Kuznyak
  • I. I. Dronik

DOI:

https://doi.org/10.26641/2307-0404.2016.4.91472

Ключевые слова:

generalized periodontitis, lipid peroxidation, immunodeficiency, biocenosis

Аннотация

Significance of processes of freelipid peroxidation, local immunological disorders and features of biocenosis of periodontal tissues and their role in the occurrence of purulent process in the periodontium in 64 patients with chronic generalized periodontitis of I-II severity degree is proved. By total of results of clinical, microbiological and metabolic studies in patients it was showed, that formation of purulent process in periodontal tissues is due to the dominance in the gingival econiche of staphylococus, fuzospiliar infection, deficiency of secretory immunity of the oral mucosa, intensity of lipid peroxidation and inhibition of antioxidant protection. It was found that the normalization of the levels of immunoglobulins, especially of sIgA, cytokines (IL-1β, TNF-α), the operation of POL and AOP are the main markers of improved clinical picture of the disease.

Биографии авторов

А. А. Gudaryan

SE «Dnipropetrovsk medical academy of Health Ministry of Ukraine»
Oral surgery, implantology and periodontology department
Dzerzhinsky str., 9, Dnipro, 49044, Ukraine

N. B. Kuznyak

SE «Bukovinian state medical university» 
Department of prosthetic dentistry
Theatralna sq., 2, Chernivtsi, 58002, Ukraine

I. I. Dronik

SE «Bukovinian state medical university»
Department of prosthetic dentistry
Theatralna sq., 2, Chernivtsi, 58002, Ukraine

Библиографические ссылки

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Muller HP. [Periodontics]. L'vov. GalDent. 2004;256. Russian.

Cochran D.L. Inflammation and bone loss in pe-riodontal disease. Periodontol. 2008;79:1569-76.

Delves PJ, Roitt IM. The immune system. Second of two parts. J Med. 2000;343:108-17.

Kebschull M, Papapanou PN. Periodontal micro-bial complexes associated with specific cell and tissue responses. J Clin Periodontol. 2011;38:17-27.

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Socransky SS, Haffajee AD. Periodontal micro-bial ecology. Periodontol 2005;38:135-187.

Загрузки

Опубликован

2016-12-22

Как цитировать

1.
Gudaryan АА, Kuznyak NB, Dronik II. Clinical, microbiological, immunological and metabolic features of purulent process occurrence in the periodontium in patients with chronic generalized periodontitis. Med. perspekt. [Интернет]. 22 декабрь 2016 г. [цитируется по 22 ноябрь 2024 г.];21(4):98-105. доступно на: https://journals.uran.ua/index.php/2307-0404/article/view/91472

Выпуск

Том 21 № 4 (2016)

Раздел

CLINICAL MEDICINE

Лицензия

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