Diagnostic capabilities of non-treponemal and treponemal reactions in the early forms of syphilis.
DOI:
https://doi.org/10.26641/2307-0404.2017.4.117679Ключові слова:
early forms of syphilis, serological diagnosis, immunoblottingАнотація
A comparative analysis of the sensitivity and specificity of immunoblotting against other non-treponemal and treponemal reactions was carried out in 215 patients with early forms of syphilis. A high diagnostic efficiency of immunoblotting in patients with early latent syphilis was established. It was found that only in case of primary syphilis, immunoblotting is inferior to Immunofluorescence reaction; this test can be used for differential diagnosis between hidden syphilis and false positive reactions to syphilis.
Посилання
Barkalova EL. [Diagnosis of neurosyphilis: the current state of the problem]. Zhurnal dermatovenerologii i kosmetologii im. N.A. Torsuyeva. 2006;1-2(12):116-9. Russian.
Barkalova OL. [Prediction of development of pathologic process in early forms of neurosyphilis]. [dissertation]. Kharkív. 2012;25. Ukrainian.
Dmitriev GA. [Syphilis. Differential clinical-laboratory diagnosis]. Moskva, Meditsina. 2004;363. Russian.
Zakharov VK, Dyudyun AD, Zakharov SV. [Latent syphilis]. Navch. рosibnyk. Dnipropetrovsʹk. 2011;121. Ukrainian.
Zakharov SV. [Social and clinical features of early latent syphilis]. Ukr. zhurnal dermatovenerologii i kosmetologii. 2010;3(58):154-5. Russian.
Frigo NV, Dudareva LV, Rotanov SV, Ivanov NM. [Immunoblotting in the diagnosis of early forms of syphilis]. Vestnik dermatologii i venerologii. 2008;3:57-62. Russian.
Katunin GL, Kitaeva AV, Frigo NV. [Features of the clinical course of neurosyphilis at the present stage]. The 3rd All-Russian Congress of Dermatovenerology. Kazan'. 2009;93. Russian.
Kubanova AA, Frigo NV, Rotanov SV. [Experience of using the immunoblot method for the diagnosis of syphilis]. Vestnik dermatologii i venerologii. 2006;2:3-11. Russian.
Kuvshinov MV, Chepurenko NV, Ritual AP. [Comprehensive approach to serological diagnosis of syphilis]. Topical issues of dermatovenereology and cosmetology: "Materials of the 5th Congress of Dermatologists and Venereologists of the Republic of Belarus. Minsk. 2006;68-71. Russian.
Mavrov GI, Shcherbakova YuV. [Latent syphilis at the present stage]. Ukr. zhurnal dermatovenerologii i kosmetologii. 2003;4(11):58-62. Russian.
Sokolovsky EV, Frigo NV, Rotanov SV. [Manual on laboratory diagnosis of syphilis in Eastern Europe]. Vestnik dermatologii i venerologii. 2011;2:87-96. Russian.
Tabuyka O, Mushet GK. [On the optimization of the diagnosis of latent syphilis]. Ukr. zhurnal dermatovenerologii i kosmetologii. 2011;1(40):78-82. Russian.
Frigo NV, Rotanov SV, Nesterenko VI. [The results of studying the diagnostic efficiency of the new test system of the linear immunoenzyme analysis "Inno-Lia TM Syphilis score"]. Klinicheskaya laboratornaya diagnostika. 2006;3:36-41. Russian.
Chereshnya VA. [Syphilis: immunity and laboratory diagnostics]. Yekaterinburg, Ur. ORAN. 2006;387. Russian.
Hagedorn H, Kramina- Hagedorn I, De Bosscherek M, et al. Evolution of INNO-LIA syphilis assay as a confirmatory Test of syphilis. I. Clin. Microbiol. 2002;40:973-8.
Ebel A, Vaneste I, Cardinaels M, et al. Validation of the INNO-LIA syphilis kitas a confimatory assay for Treponema pallidum antibodes. I. Clin. Microbiol. 2000;38:215-9.
Sambri V, Marandony A, Eger C, et al. Western immunobloting with five Treponema pallidum antigens for diagnosis by western blotting technique. CVI. 2001;8:534-9.
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