Chronic comorbidity of internal organs as a risk factor of complications and fatal outcome of community-acquired pneumonia.

Автор(и)

  • Y. M. Mostovoy
  • A. V. Demchuk
  • T. V. Konstantynovych
  • K. D. Chichirelo-Konstantynovych

DOI:

https://doi.org/10.26641/2307-0404.2018.1(part1).127248

Ключові слова:

community-acquired pneumonia, chronic diseases of internal organs

Анотація

With the purpose to estimate influence of comorbidity at the risk of complications and death due to community-acquired pneumonia (CAP) the retrospective analysis of 1587 case histories of inpatients with CAP (mean age – 48.5±18.4, males – 815 (51.4%), women – 772 (48,6%)) was performed. Comorbidity was observed in 1114 (70.2%). More frequently complications of CAP were developed in patients with chronic diseases than without them (p=0.013). Increased risk of pleural effusion was associated with chronic diseases of digestive system (OR=1.85 (95%CI 1.30-2.26)) and diabetes mellitus (OR=2.35 (95%CI 1.40-3.96)). Risk of sepsis development is higher in patients with nervous system diseases (OR=3.62 (95%CI 1.37-9.56) and drug or alcohol addiction (OR=19.08 (95%CI 7.30-49.82). Risk of pulmonary edema rose in patients with drug or alcohol addiction (OR=24.16; 95%CI 8.07-72.34), malignancy (OR=8.97; 95%CI 1.94-41.49), diabetes mellitus (OR=4.04; 95%CI 1.48-11.01), diseases of nervous (OR=4.04; 95%CI 1.17-13.94), urinary (OR=3.39; 95%CI 1.33-8.64) and cardiovascular (OR=2.29, 95%CI 0.98-5.34) systems. Higher risk of death in patients with CAP was associated with the presence of cardiovascular diseases (OR=2.17; 95%CI 1.11-4.25), diabetes mellitus (OR=2.95; 95%CI 1.20-7.21), drug or alcohol addiction (OR=38.40; 95%CI 15.05-97.98).

 

Біографії авторів

Y. M. Mostovoy

National Pirogov Memorial Medical University, Vinnytsya
Department of Propaedeutics internal medicine
Pirogova str, 56, Vinnytsya, 21018, Ukraine

A. V. Demchuk

National Pirogov Memorial Medical University, Vinnytsya
Department of Propaedeutics internal medicine
Pirogova str, 56, Vinnytsya, 21018, Ukraine

T. V. Konstantynovych

National Pirogov Memorial Medical University, Vinnytsya
Department of Propaedeutics internal medicine
Pirogova str, 56, Vinnytsya, 21018, Ukraine

K. D. Chichirelo-Konstantynovych

National Pirogov Memorial Medical University, Vinnytsya
Department of Propaedeutics internal medicine
Pirogova str, 56, Vinnytsya, 21018, Ukraine

Посилання

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Як цитувати

1.
Mostovoy YM, Demchuk AV, Konstantynovych TV, Chichirelo-Konstantynovych KD. Chronic comorbidity of internal organs as a risk factor of complications and fatal outcome of community-acquired pneumonia. Med. perspekt. [інтернет]. 24, Квітень 2018 [цит. за 23, Листопад 2024];23(1(part1):112-7. доступний у: https://journals.uran.ua/index.php/2307-0404/article/view/127248

Номер

Том 23 № 1(part1) (2018)

Розділ

КЛІНІЧНА МЕДИЦИНА

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