Bronchial asthma in children of Ukraine: medical and environmental parallels of morbidity and prevalence
DOI:
https://doi.org/10.26641/2307-0404.2020.3.214861Ключові слова:
children, incidence, prevalence, bronchial asthma, environment, pollutantsАнотація
Bronchial asthma is one of the most common non-infectious diseases of children worldwide. More than half of such clinical cases may lead to functional disability and significantly affects the quality of life of a sick child. The aim of the study was to research trends in the incidence and prevalence of bronchial asthma among children in different regions of Ukraine over the past 25 years and assess the effect of air pollutant emissions from stationary sources in the region of children residence on the incidence and prevalence of bronchial asthma among them. According to the Center for Medical Statistics of the Ministry of Health of Ukraine, the incidence of bronchial asthma among children aged 0-17 years was 4513 0.59 of new cases per 1000 population in 2017. Prevalence of this disease was 37246 cases (4.91 per 1000 population). The majority of newly diagnosed bronchial asthma cases was observed in children aged 7-14 years – 2439 or 54.0% of the total, which is in line with global trends. The highest incidence and prevalence in all three age groups was observed among children of Kyiv and Kharkiv, Zaporizhia, Vinnitsa, Dnipropetrovsk, Donetsk regions. We have discovered a direct and close connection (ρ=0.741) between the reduction of air pollutant emissions from stationary sources and decreasing of the prevalence of bronchial asthma among children in recent years. Over the past 25 years in Ukraine there has been 69.3% increase in prevalence and 22.9% increase in incidence of bronchial asthma among children. Predominance of detecting this pathology was in the group of children from large industrial and agro-industrial regions of the country with significant volumes of atmospheric pollutants from stationary sources of pollution.Посилання
Antypkin YuH, Chumachenko NH, Umanets TR, Lapshyn VF. [Analysis of the incidence and prevalence of bronchial asthma in children of different ages in the regions of Ukraine]. Perinatologiya i pediatriya. 2016;1(65):95-99. Ukrainian.
[Recommendations of the Bioethics Committee under the Presidium of the National Academy of Medical Sciences of Ukraine]. NAMS of Ukraine. 2002:18. Ukrainian.
Serdyuk AM, Stus VP, Lyashenko VI. [Ecology of the environment and safety of life of the population in the industrial regions of Ukraine]. Dnipropetrovsk: Porohy. 2011:486. Ukrainian.
Gehring U, Gruzieva O, Agius RM, Beelen R, et al. Air Pollution Exposure and Lung Function in Children: The ESCAPE Project. Environ Health Perspect. 2013 Nov-Dec;121(11-12):1357-64. doi: https://doi.org/10.1289/ehp.1306770
Аsher M, Weiland S. The International Study of Asthma and Allergy in Childhood – ISAAC. Clin. Exsp. Allergy.1998;28:52-66. doi: https://doi.org/10.1046/j.1365-2222.1998.028s5052.x
Fulekar MH., editor, Bioinformatics: Applica-tions in Life and Environmental Sciences, Springer. 2009;110. ISBN 1-4020-8879-5.
CME Exam: Severe Asthma in Children. The Journal of Allergy and Clinical Immunology: In Practice. 2017 Jul.-Aug.;5(4):899-900. doi: https://doi.org/10.1016/j.jaip.2017.05.012
Convention on Human Rights and Biomedicine. Available from: https://www.coe.int/en/web/conventions/full-list/-/conventions/rms/090000168007d004)
Dharmage SC, Perret JL, Custovic A. Epidemiology of Asthma in Children and Adults – Frontiers in Pediatrics. 2019;7:246. doi: https://doi.org/10.3389/fped.2019.00246
Eder W, Ege MJ, von Mutius E. The asthma epidemic. N Engl J Med. 2006;355:2226-35. doi: https://doi.org/10.1056/NEJMra054308
Environment of Ukraine. Statistical yearbook. State Statistics Service of Ukraine. Kyiv. 2018:225.
Global strategy for asthma management and prevention. National institutes of health. National Heart, lung and Blood Institute. Revised 2016. Available from: http://www.ginasthma.org
Hamelmann E, von Mutius E, Bush A, Szefler S. Addressing the Risk Domain in the Long-Term Mana-gement of Pediatric Asthma. Pediatr Allergy Immunol. 2020 Apr;31(3):233-42
Network GA. The Global Asthma Report, Auck-land, New Zealand; 2018
Puranik S, Forno E, Bush A, Celedón JС. Predic-ting Severe Asthma Exacerbations in Children. Am J Respir Crit Care Med. 2017 Apr 1;195(7):854-9. doi: https://doi.org/10.1164/rccm.201606-1213PP
Rodgers JL, Nicewander WA. Thirteen ways to look at the correlation coefficient. The American Statis-tician. 1988 Febr;42(1):59-66, doi: https://doi.org/10.1080/00031305.1988.10475524
Rusconi F, Fernandes RM, Pijnenburg M.Wh., Grigg J. SPACE Clinical Research Collaboration; Euro-pean Lung Foundation severe asthma patient advisory group. The Severe Paediatric Asthma Collaborative in Europe (SPACE) ERS Clinical Research Collaboration: Enhancing Participation of Children With Asthma in Therapeutic Trials of New Biologics and Receptor Blockers. Eur Respir J. 2018 Oct 18;52(4):1801665. doi: https://doi.org/10.1183/13993003.01665-2018
Tatum AJ, Shapiro GG. The effects of outdoor air pollution and tobacco smoke on asthma. Immunol Allergy Clin North Am. 2005;25:15-30. doi: https://doi.org/10.1016/j.iac.2004.09.003
Volosovets OP, Kryvopustov SP, Volosovets TM, Abaturov OE, Kryuchko TO. Changes in health status of child population of Ukraine after Chernobyl catastrophe. Wiadomości Lekarskie. 2019;LXXII(10):1974-76. doi: https://doi.org/10.36740/WLek201910123
World Medical Association, Declaration of Helsinki: Ethical Principles for Medical Research Involving Human subjects, JAMA. 2013;310(20):2191-4. doi: https://doi.org/10.1001/jama.2013.281053
##submission.downloads##
Опубліковано
Як цитувати
Номер
Розділ
Ліцензія
Авторське право (c) 2020 Медичні перспективи
Ця робота ліцензується відповідно до Creative Commons Attribution 4.0 International License.
Submitting manuscript to the journal "Medicni perspektivi" the author(s) agree with transferring copyright from the author(s) to publisher (including photos, figures, tables, etc.) editor, reproducing materials of the manuscript in the journal, Internet, translation into other languages, export and import of the issue with the author’s article, spreading without limitation of their period of validity both on the territory of Ukraine and other countries. This and other mutual duties of the author and all co-authors separately and editorial board are secured by written agreement by special form to use the article, the sample of which is presented on the site.
Author signs a written agreement and sends it to Editorial Board simultaneously with submission of the manuscript.
