Features of resistance of major pathogens of respiratory tract infections in Dnipropetrovsk region.

T. O. Pertseva; T. V. Kireyeva; O. V. Bratus; O. O. Shtepa; O. V. Yuvko

doi:10.26641/2307-0404.2014.1.24412

Автор(и)

T. O. Pertseva
T. V. Kireyeva
O. V. Bratus
O. O. Shtepa
O. V. Yuvko

DOI:

https://doi.org/10.26641/2307-0404.2014.1.24412

Ключові слова:

resistance, antibacterial drugs, infectious agents, respiratory tract infections, Streptococcus pneumoniae, Hаemophilus influenzae

Анотація

According to the retrospective analysis of data obtained for the period of the last four years, the resistance level of major infectious agents (Streptococcus pneumoniae, Hаemophilus influenzaе) to the most of commonly used classes of antibacterial agents (β-lactams, macrolides, lincosamides, fluoroquinolones) was rather low, except for the established resistance level of penicillin-resistant Streptococcus pneumoniae (19% of tested strains were resistant to oxacillin). Multiply resistance of Streptococcus pneumoniae strains in Dnipropetrovsk region was 4,3%. Prognosed by world-wide trials growth of bacterial resistance levels requires decrease of the irrational antibiotics using and constant monitoring of resistance in each region and in the country as a whole to preserve the potential of clinical effective antibacterial agents.

Біографії авторів

T. O. Pertseva

SE "Dnipropetrovsk medical academy of Health Ministry of Ukraine"¹
Department of Faculty Therapy and Endocrinology
Dzerzhinsky str. 9, Dnipropetrovsk, 49044, Ukraine

T. V. Kireyeva

SE "Dnipropetrovsk medical academy of Health Ministry of Ukraine"¹
Department of Faculty Therapy and Endocrinology
Dzerzhinsky str. 9, Dnipropetrovsk, 49044, Ukraine

O. V. Bratus

Diagnostic center LLC“Pharmacies of medical academy”²Zhovtneva sq., 4, Dnipropetrovsk, Ukraine, 49027

O. O. Shtepa

SE "Dnipropetrovsk medical academy of Health Ministry of Ukraine"¹
Department of Faculty Therapy and Endocrinology
Dzerzhinsky str. 9, Dnipropetrovsk, 49044, Ukraine

O. V. Yuvko

Diagnostic center LLC“Pharmacies of medical academy”²Zhovtneva sq., 4, Dnipropetrovsk, Ukraine, 49027

Посилання

Антибиотикорезистентность Streptococcus pneu¬mo¬nia в России в 1999 – 2005гг: результаты мно¬гоцентровых проспективных исследований ПеГАС-I ПеГАС-II / Р.С. Козлов, О.В. Сивая, К.В. Шпынев [и др.] // Клинич. микробиология. Антимикробная хи¬мио¬терапия. – 2006. – Т. 8, № 1. – С. 33–47.

Дзюблик Я.О. Антибіотикорезистентність збуд¬ників інфекцій дихальних шляхів: огляд ре¬зультатів дослідження SOAR та перспективи мікро¬біологічного моніторингу в Україні / Я.О. Дзюблик // Укр. пульмонол. журнал – 2010. – № 4. – С. 33–35.

Дзюблик Я.О. Клінічні аспекти антибіоти¬ко¬резистентності збудників негоспітальних інфекцій ди¬хальних шляхів / Я.О. Дзюблик // Укр. пульмонол. журнал – 2010. – № 3. – С. 53–56.

Негоспітальна пневмонія у дорослих осіб: етіо¬логія, патогенез, класифікація, діагностика, ант¬и¬бак¬теріальна терапія (проект клінічних настанов) Час¬тина 2 / Ю.І. Фещенко, О.А. Голубовська К.А. [та ін.] // Укр. пульмонол. журнал. – 2013. – № 1. – С.5–17.

Перцева Т.О. Анамнестичні та клініко-функціональні особливості перебігу хронічного обструктивного захворювання легень у залежності від характеру й ступеня мікробного навантаження нижніх дихальних шляхів / Т.О. Перцева, Л.І. Конопкіна // Укр. пульмонол. журнал. – 2009. – № 2. – С. 26–30.

Страчунский Л.С. Практическое руководство по антиинфекционной химиотерапии / Л.С. Стра¬чунский, Ю.Б. Белоусова, С.Н. Козлова. – Смоленск: МАКМАХ, 2007. – 464 с.

A survey of antibiotic resistance in Streptococcus pneumoniae and Haemophilus influenzae in Turkey, 2004–2005 / S. Burcin, T. Ferda, U. Sercan [et al.] // J. Antimicrob. Chemother. – 2007. – Vol. 60. – P. 587–593.

Adolf W. Karchmer. Increased Antibiotic Re¬sistance in Respiratory Tract Pathogens: PROTEKT US—An Update / W. Adolf // Clin. Infect. Diseases. – 2004. – Vol. 39. – P. 142–150.

And the Alexander Project Group. The Alexander Project 1998–2000: susceptibility of pathogens isolated from community-acquired respiratory tract infection to commonly used antimicrobial agents / Michael R. Jacobs [et al.] // J. Antimicrob. Chemother. – 2003. – Vol. 52. – P. 229–246.

Annual report of the European Antimicrobial Resistance Surveillance Network (EARS-Net) 2012 / Euro¬pean Centre for Disease Prevention and Control. –2013. – 205 p.

ANSORP Study Group. Changing trends in antimicrobial resistance and serotypes of Streptococcus pneumoniae isolates in Asian countries: an Asian Net¬work for Surveillance of Resistant Pathogens (ANSORP) stu¬dy / Kim S.H., Song J.H., Chung D.R. [et al.] // Antimicrob. Agents Chemother. – 2012. – Vol. 56. – P. 1418–1426.

Antimicrobial resistance among Streptococcus pneu¬moniae and Haemophilus influenzae isolates in the United Arab Emirates: 2004-2006 / Abiola Senok, Mansour Al-Zarouni [et al.] // J. Infect. Developing Countries. – 2007. – Vol. 1, N 3. – P. 296–302.

Relationship between Antibiotic Resistance in Streptococcus pneumoniae and That in Haemophilus in¬fluenzae: Evidence for Common Selective Pressure / Mark E. Jones [et al.] // Antimicrob. Agents Chemother. – 2002. – Vol. 46, N 9. – P. 3106.

Robert C. The Continuing Chal¬lenge of Lower Respiratory Tract Infections / Robert C. Moel¬lering Jr. // Clin. Infect. Dis. – 2002. – Vol. 34. – P.1–3.

Survey of Susceptibilities of Streptococcus pneu¬moniae, Haemophilus influenzae, and Moraxella catar¬rhalis Isolates to 26 Antimicrobial Agents: a Prospective U.S. Study / C. Thornsberry, P. T. Ogilvie, H. P. Holley jr., D. F. Sahm. // Antimicrob. Agents Chemother. – 1999. – N 11. – P. 2612–2623.

Kozlov RS, Sivaya OV, Shpynev KV. [Antibiotic resistance in Streptococcus pneumonia in Russia in 1999-2005: results of multicenter prospective studies PeGAS-I PeGAS-II]. Klinicheskaya mikrobiologiya. Antimikrob¬naya khimioterapiya. 2006;8(1):33–47. Russian.

Dzyublik YaO. [Antibiotic resistance of patho¬gens of respiratory tract infections: a review of SOAR research results and prospects of microbiological moni¬toring in Ukraine]. Ukr. pul'monol. zhurn. 2010;4:33–35. Ukrainian.

Dzyublik YaO. [Clinical aspects of antimicrobial agents of community acquired respiratory tract infec¬tions]. Ukr. pul'monol. zhurn. 2010;3:53-56. Ukrainian.

Feshchenko YuІ, Golubovs'ka KA. [Community acquired pneumonia in adults: etiology, pathogenesis, classification, diagnosis, antibiotic therapy (project of cli¬nical guidelines) Part 2]. Ukraїns'kiy pul' monologіchniy zhurnal. 2013;1:5–17. Ukrainian.

Pertseva TO, Konopkіna LІ. [Anamnestic and clinical and functional features of chronic obstructive pulmonary disease, depending on the nature and extent of microbial load of the lower respiratory tract]. Ukr. pul'mo¬nol.zhurn. 2009;2:26–30. Ukrainian.

Strachunskiy LS, Belousova YuB, Kozlova SN. [Practical guidance on anti-infective chemotherapy]. Smo¬lensk: MAKMAH; 2007:464. Russian.

Burcin S, Ferda T, Sercan U. A survey of anti¬biotic resistance in Streptococcus pneumoniae and Haemo¬philus influenzae in Turkey, 2004–2005. Journal of Antimicrobial Chemotherapy. 2007;60:587–93.

Adolf W. Karchmer. Increased Antibiotic Resis¬tance in Respiratory Tract Pathogens: PROTEKT US—An Update. Clinical Infectious Diseases. 2004;39:142–50.

Michael R. Jacobs and the Alexander Project Group. The Alexander Project 1998–2000: susceptibility of pathogens isolated from community-acquired res¬piratory tract infection to commonly used antimicrobial agents. Journal of Antimicrobial Chemotherapy. 2003;52:229–46.

Annual report of the European Antimicrobial Resistance Surveillance Network (EARS-Net) 2012. Euro¬pean Centre for Disease Prevention and Control. 2013:205.

Kim SH, Song JH, Chung DR. ANSORP Study Group. Changing trends in antimicrobial resistance and serotypes of Streptococcus pneumoniae isolates in Asian countries: an Asian Network for Surveillance of Resistant Pathogens (ANSORP) study. Antimicrob. Agents Che¬mother. 2012;56:1418–26.

Abiola Senok, Mansour Al-Zarouni. Antimic¬ro¬bial resistance among Streptococcus pneumoniae and Haemophilus influenzae isolates in the United Arab Emirates: 2004-2006. J. Infect. Developing Countries. 2007;1(3):296–302.

Mark E Jones. Relationship between Antibiotic Resistance in Streptococcus pneumoniae and That in Haemophilus influenzae: Evidence for Common Selective Pres¬sure Antimicrob. Agents Chemother. 2002;46(9):3106.

Robert C. Moellering Jr. The Continuing Chal¬lenge of Lower Respiratory Tract Infections. Clin Infect Dis. 2002;34:1–3.

Thornsberry C, Ogilvie PT, Holley HP, Sahm DF. Survey of Susceptibilities of Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis Iso¬lates to 26 Antimicrobial Agents: a Prospective U.S. Study. Antimicrobial Agents and Chemotherapy. 1999;11:2612–23.