Socio-demographic characteristics of patients with negative and positive symptoms in schizophrenia
DOI:
https://doi.org/10.26641/2307-0404.2024.1.301142Ключові слова:
socio-demographic characteristics, patients with schizophrenia, negative symptoms, positive symptoms, clinical and anamnestic analysisАнотація
Schizophrenia is a severe mental disorder that leads to impaired social adaptation, interpersonal interaction, and disability. Negative symptoms are an integral part of schizophrenia. In the world psychiatric science and practice, there are still many questions about the typology of schizophrenia, the description of its clinical manifestations, first of all, the features of negative symptoms in schizophrenia. Psychiatrists of different countries draw attention to the fact that these descriptions do not always coincide. Socio-demographic factors can be considered as factors affecting the prognosis of the course and outcome of schizophrenia. In this regard, a comprehensive approach to the study of socio-demographic characteristics of patients with schizophrenia involves the study of the influence of social factors on the formation and course of schizophrenia and determines the relevance of this study. The purpose of the study was to determine the features of socio-demographic characteristics of patients with schizophrenia in order to improve diagnosis and create psycho-corrective measures. 252 patients with negative symptoms of schizophrenia and 79 patients with positive symptoms of schizophrenia were examined. During the research, a comprehensive approach was used, consisting in the use of clinical-psychopathological, clinical-anamnestic and statistical research methods.
Socio-demographic features of patients with negative symptoms in schizophrenia were established, consisting in the predominance of women; patients aged 20-29 years; persons with special secondary education; divorced and single persons; patients busy with physical labor; average level of material wealth; very poor and poor living conditions. Socio-demographic characteristics of patients with positive symptoms in schizophrenia were outlined by the predominance of men; patients aged 30-49 years; persons with incomplete higher education and with higher education; divorced and single persons; patients with disabilities; with extremely low and low levels of material well-being and a satisfactory level of living conditions. The conducted research made it possible to draw conclusions that socio-demographic features of patients with negative and positive symptoms have their own specificity, which should be taken into account when diagnosing patients with schizophrenia.
Посилання
Jaeschke K. Global estimates of service coverage for severe mental disorders: findings from the WHO Mental Health Atlas 2017. Glob Ment Health. 2021;8:e27. doi: https://doi.org/10.1017/gmh.2021.19
Haigh SM, Coffman BA, Salisbury DF. Mismatch Negativity in First-Episode Schizophrenia: A Meta-Analysis. Clinical EEG and neuroscience. 2017;48(1):3-10. doi: https://doi.org/10.1177/1550059416645980
Kushnir YuA. [Clinical and anamnestic characte-ristics of patients with negative symptoms in schi-zophrenia]. Ukrainskyi visnyk psykhonevrolohii. 2023;31:3(116):78-84. Ukrainian. doi: https://doi.org/10.36927/2079-0325-V31-is3-2023-13
Correll CU, Schooler NR. Negative Symptoms in Schizophrenia: A Review and Clinical Guide for Recog-nition, Assessment, and Treatment. Neuropsychiatr Dis Treat. 2020;16:519-34. doi: https://doi.org/10.2147/NDT.S225643
Galderisi S, Mucci A, Buchanan RW, Arango C. Negative symptoms of schizophrenia: new developments and unanswered research questions. Lancet Psychiatry. 2018;5:664-77. doi: https://doi.org/10.1016/S2215-0366(18)30050-6
Blanchard JJ, Bradshaw KR, Garcia CP, Nasral-lah HA, Harvey PD, et al. Examining the reliability and validity of the Clinical Assessment Interview for Negative Symptoms within the Management of Schizophrenia in Clinical Practice (MOSAIC) multisite national study. Schizophrenia research. 2017;185:137-43. doi: https://doi.org/10.1016/j.schres.2017.01.011
Shvets KN, Khamska IS. [Factors of social disadaptation of patients with schizophrenia and approaches to psychosocial therapy and rehabilitation (look back)]. Scientific results of biomedical research. 2019;5(2):72-85. doi: https://doi.org/10.18413/2658-6533-2019-5-2-0-8
Lee WH, Doucet GE, Leibu E, Frangou S. Resting-state network connectivity and metastability predict clinical symptoms in schizophrenia. Schizophrenia research. 2018;201:208-16. doi: https://doi.org/10.1016/j.schres.2018.04.029
Bucci P, Galderisi S. Categorizing and assessing negative symptoms. Current opinion in psychiatry. 2017;30(3):201-8. doi: https://doi.org/10.1097/YCO.0000000000000322
Galderisi S, Kaiser S, Bitter I, Nordentoft M, et al. EPA guidance on treatment of negative symptoms in schizophrenia. European psychiatry: the journal of the Association of European Psychiatrists. 2021;64(1):e21. doi: https://doi.org/10.1192/j.eurpsy.2021.13
Almulla AF, Al-Hakeim HK, Maes M. Schizophrenia phenomenology revisited: positive and negative symptoms are strongly related reflective manifestations of an underlying single trait indicating overall severity of schizophrenia. CNS spectrums. 2021;26(4):368-77. doi: https://doi.org/10.1017/S1092852920001182
Riehle M, Mehl S, Lincoln TM. The specific social costs of expressive negative symptoms in schizophrenia: reduced smiling predicts interactional outcome. Acta psychiatrica Scandinavica. 2018;138(2):133-44. doi: https://doi.org/10.1111/acps.12892
Sabe M, Kirschner M, Kaiser S. Prodopaminergic Drugs for Treating the Negative Symptoms of Schizophrenia: Systematic Review and Meta-analysis of Ran-domized Controlled Trials. Journal of clinical psycho-pharmacology. 2019;39(6):658-64. doi: https://doi.org/10.1097/JCP.0000000000001124
[ICD 10 – International Classification of Diseases, 10th revision]. [Internet]. [cited 2023 Aug 20]. Russian. Available from: https://mkb-10.com/index.php?pid=4001
Skrypnikov AM, Zhyvotovska LV, Bodnar LA, Sonnyk HT. [Psychiatry and narcology: educational and methodological manual]. 2-e vydannia. 2021. 224 p. Ukrainian.
Walters SJ, Campbell MJ, Machin D. Medical Statistics: A Textbook for the Health Sciences. 5th ed. Wiley-Blackwell; 2021. 448 p.
Altynbekov K, Raspopova N, Abetova A. Analysis of social and demographic and clinical characteristics of patients with paranoid schizophrenia of the kazakh ethnic group in the republic of Kazakhstan. Georgian Med News. 2023 May;338:6-13. PMID: 37419463.
Vita A, Barlati S. Recovery from schizophrenia: is it possible? Curr Opin Psychiatry. 2018 May;31(3):246-55. doi: https://doi.org/10.1097/YCO.0000000000000407
Zhang CX, Ren XH, Yang XM, Fan RX, Wang Y, Li YL, et al. [Quality of Life and Its Influencing Factors Among Schizophrenia Patients Living in Urban and Rural Areas]. Sichuan Da Xue Xue Bao Yi Xue Ban. 2023 May;54(3):608-13. Chinese. doi: https://doi.org/10.12182/20230560202
Coulibaly SDP, Ba B, Mounkoro PP, Diakite B, Kassogue Y, Maiga M, et al. Descriptive study of cases of schizophrenia in the Malian population. BMC Psychiatry. 2021 Aug 20;21(1):413. doi: https://doi.org/10.1186/s12888-021-03422-9
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