Features of change of intracardiac gemodynamics and functional state of myocardium under the impact of telmisartan in patients with hypertension.

Автор(и)

  • V. I. Koshlia
  • M. Ben-Abid

DOI:

https://doi.org/10.26641/2307-0404.2016.3.82007

Ключові слова:

essential hypertension, hemodynamics, telmisartan

Анотація

In 41 patients with essential hy­pertension I and II degrees telmisartan influence on parameters of intimate heodynamics and functional condition of myocardium ofLVhas been studied. Carried out researches have shown, that on a background of treatment with telmisartan reduction of final diastolic volume of LV, final systolic meredional stress and final diastolic pressure of the myocardium and increase in fraction of LV ejection emission and speed of circular reduction of myocardium fibres is marked. The specified changes may be explained by improvement of plastic characteristics of the myocardium that is caused both by direct action of telmisartan on the myocardium through blockade of a local renin-angiotensin- aldosterone system, and by the mediated influence due to decrease of blood pressure and after post loading.

Біографії авторів

V. I. Koshlia

Zaporozhye Medical Academy of Postgraduate Education
Department of Family Medicine with courses dermatology and psychiatry
Vintera boul., 20, Zaporozhye, 69096, Ukraine

M. Ben-Abid

Zaporozhye Medical Academy of Postgraduate Education
Department of Family Medicine with courses dermatology and psychiatry
Vintera boul., 20, Zaporozhye, 69096, Ukraine

Посилання

Afanasjuk OІ. [Reaching the target blood pressure in patients with hypertension with comorbid diabetes mellitus type 2 after standard treatment complex]. Bukovins'kij medichnij vіsnik. 2014;2(70):3-6. Ukrainian.

Drapkina OM. [Angiotensin receptor antagonists in treating cardiovascular diseases]. Spravochnik polikli-nicheskogo vracha. 2008;5:22-24. Russian.

Kobalava ZhD. [European guidelines on hyper-tension]. Kardiologija. 2013;12:83-93. Russian.

Konradi AO, Zaharov DA, Rudomanov OG. [Estimation of the prevalence of myocardial remodeling in hypertension using different echocardiographic criteria]. Arterial'naja gipertenzija. 2012;1(7):20-27. Russian.

Svіshhenko EP, Bagrіj AE, Єna LM. [Hyper¬en-sion adapted and updated clinical guidelines based on evidence-2012]. Nov. med. i farmacii. 2012;12(422):12-58. Ukrainian.

Ruzov VI, Gimaev RH, Razin VA, et al. [The structural and functional state of the myocardium and indicators of signal-averaged electrocardiogram in pa-tients with hypertension]. Kardiovaskuljarnaja terapija i profilaktika. 2005;6:(II):21-26. Russian.

Shilov AM. [Sartans in the practice of primary care physicians in the treatment of hypertension]. Farma-teka. 2014;9:17-21. Russian.

ACCORD Study Group. Effects of intensive bloodpressure control in type 2 diabetes mellitus. N. Engl. J. Med. 2010;362:1575-85.

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Опубліковано

2015-09-27

Як цитувати

1.
Koshlia VI, Ben-Abid M. Features of change of intracardiac gemodynamics and functional state of myocardium under the impact of telmisartan in patients with hypertension. Med. perspekt. [інтернет]. 27, Вересень 2015 [цит. за 23, Листопад 2024];21(3):26-9. доступний у: https://journals.uran.ua/index.php/2307-0404/article/view/82007

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