Application of cytogenetic researches in efficiency assessment of vaccines against leukemia virus in cattle
DOI:
https://doi.org/10.15587/2313-8416.2018.121096Keywords:
genetic monitoring, cattle leukemia virus, immunogenesis, mice, bone marrow cellsAbstract
We studied the effect of immunogens of the leukemia virus in cattle on the cytogenetic parameters of bone marrow in the dynamics of immunogenesis. We found that each drug has its own specific effect, which is due to the structural differences of the leukemia virus in cattle. The method of cytogenetic studies of bone marrow cells should be used to assess the safety and immunogenic properties of retroviral origin drugs
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