Активность протеасом в клетках поджелудочной железы при экспериментальном панкреатите
DOI :
https://doi.org/10.15587/2313-8416.2015.53177Mots-clés :
протеасома, химотрипсиноподобная активность, трипсиноподобная активность, каспазоподобная активность, поджелудочная железа, панкреатитRésumé
Исследовано химотрипсино-, трипсино- и каспазоподобную протеасомальные активности в клетках поджелудочной железы и установлено их изменение при экспериментальном панкреатите – повышение химотрипсиноподобной АТФ-независимой активности на фоне снижения трипсиноподобной и каспазоподобной активностей. При этом, снижение трипсиноподобной активности происходило за счет АТФ-зависимого гидролиза, тогда как каспазоподобной – за счет АТФ-независимого гидролиза
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(c) Tous droits réservés Мария Александровна Тимошенко, Олеся Вадимовна Сокур, Татьяна Владимировна Коваль, Лариса Ивановна Богун 2015
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