Активность протеасом в клетках поджелудочной железы при экспериментальном панкреатите
DOI:
https://doi.org/10.15587/2313-8416.2015.53177Słowa kluczowe:
протеасома, химотрипсиноподобная активность, трипсиноподобная активность, каспазоподобная активность, поджелудочная железа, панкреатитAbstrakt
Исследовано химотрипсино-, трипсино- и каспазоподобную протеасомальные активности в клетках поджелудочной железы и установлено их изменение при экспериментальном панкреатите – повышение химотрипсиноподобной АТФ-независимой активности на фоне снижения трипсиноподобной и каспазоподобной активностей. При этом, снижение трипсиноподобной активности происходило за счет АТФ-зависимого гидролиза, тогда как каспазоподобной – за счет АТФ-независимого гидролиза
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