Генетические варианты микобактерий туберкулеза и их эпидемиологическая значимость

Авторы

  • Александр Алексеевич Ляшенко Харьковская медицинская академия последипломного образования ул. Корчагинцев 58, г. Харьков, Украина, 61176, Ukraine

DOI:

https://doi.org/10.15587/2313-8416.2015.38954

Ключевые слова:

микобактерии туберкулеза, генотипы, эпидемиология, Beijing, LA-M, Haarlem, распространенность, клинические особенности

Аннотация

С помощью основных молекулярно-биологических методов можно проводить типирование M. tuberculosis. Обнаружено более 2000 различных генотипов, некоторые из них распространены повсеместно, другие встречаются реже или характерны для какого-то конкретного региона. Так, наиболее распространенным генотипом является Beijing, несколько реже встречается LA-M и Haarlem. С генотипом Beijing часто связывают неблагоприятное течение туберкулеза и более частое обнаружение устойчивости к противотуберкулезным препаратам

Биография автора

Александр Алексеевич Ляшенко, Харьковская медицинская академия последипломного образования ул. Корчагинцев 58, г. Харьков, Украина, 61176

Кандидат медицинских наук, доцент

Кафедра фтизиатрии и пульмонологии

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Опубликован

2015-03-19

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Раздел

Медицинские науки