Possibility of using the complex of phytopreparates, vitamins and microelements in the treatment of chronic abacterial prostatitis

Authors

  • Andrey Minukhin National University of Pharmacy Pushkinska str., 53, Kharkiv, Ukraine, 61002, Ukraine
  • Vladimir Bondarenko State Institution "V. Ya. Danilevsky Institute for Endocrine Pathology Problems of the National Academy of Medical Sciences of Ukraine" Artema str., 10, Kharkiv, Ukraine, 61002, Ukraine
  • Nadiia Kononenko National University of Pharmacy Pushkinska str., 53, Kharkiv, Ukraine, 61002, Ukraine

DOI:

https://doi.org/10.15587/2519-4798.2018.124680

Keywords:

chronic abacterial prostatitis, "index of symptoms of chronic prostatitis", Saluprost, spermogram, testosterone, estradiol

Abstract

Aim of the research was to study the effectiveness of the complex drug "Saluprost" with chronic prostatitis on the parameters of spermogram and sex hormones levels in young men.

Methods. The state of the prostate gland, the parameters of spermograms, as well as the levels of hormones when using the complex drug "Saluprost", which contains phytonutrients, vitamins and trace elements, were studied. The efficacy of treatment was evaluated by studying the index of symptoms of chronic prostatitis (NHI-CPSI). Parameters of spermograms were studied according to WHO criteria. Testing levels of testosterone and estradiol in the blood was carried out using the immune enzyme method.

Results. Against the background of a decrease in the N1H-CPSI index, which characterizes the severity of the manifestations of chronic prostatitis, the parameters of the spermogram were improved: the mean values of the concentration of sperm, the percentage of their mobile and active forms, and the mean values of morphologically altered forms of sperm decreased. This happened on the background of increasing and normalizing the mean values of the concentration of fructose in the ejaculate. Therapy helped to make estradiol levels lower in serum, as well as a significant increase in mean testosterone levels.

Conclusions. The drug "Saluprost" is effective in the treatment of chronic abacterial prostatitis. It also has a positive effect on the studied parameters of spermograms and androgen-estrogen balance in young men

Author Biographies

Andrey Minukhin, National University of Pharmacy Pushkinska str., 53, Kharkiv, Ukraine, 61002

PhD, Assistant

Department of Pathological Physiology

Vladimir Bondarenko, State Institution "V. Ya. Danilevsky Institute for Endocrine Pathology Problems of the National Academy of Medical Sciences of Ukraine" Artema str., 10, Kharkiv, Ukraine, 61002

MD, Professor

Department of pathology of sexual glands

Nadiia Kononenko, National University of Pharmacy Pushkinska str., 53, Kharkiv, Ukraine, 61002

MD, Professor

Department of Pathological Physiology

References

  1. Gorpinchenko, I. I., Gurzhenko, Yu. N. (2011). Ispol'zovanie suppozitoriev Vitaprost forte i Vitaprost v kompleksnom lechenii bol'nyh hronicheskim prostatitom. Zdorov'e muzhchiny, 4, 87–94.
  2. Lytvynets, Ye. A., Lytvynets, V. Ye., Babeliuk, V. V., Babeliuk, N. V. (2014). Efektyvnist fitopreparatu ambovit u likuvanni khvorykh na khronichnyi abakterialnyi prostatyt. Zdorov'e muzhchiny, 3, 88–90.
  3. Povorozniuk, M. V. (2015). Prychyny porushen reproduktyvnoho zdorovia u cholovikiv iz bezpliddiam. Zdorov'e muzhchiny, 3, 162–165.
  4. Gorpinchenko, I. I., Gurzhenko, Yu. N. (2015). Metabolicheskaya terapiya v kompleksnom lechenii ekskretorno-toksicheskogo besplodiya u muzhchin. Opyt primeneniya preparata Gammafertil. Zdorov'e muzhchiny, 3, 134–138.
  5. Nikitin, O. D. (2010). Vozmozhnosti antigomotoksicheskoy terapii ekskretorno-toksicheskogo besplodiya u bol'nyh hronicheskim prostatitom. Zdorov'e muzhchiny, 2, 229–232.
  6. Hurzhenko, Yu. M., Spyrydonenko, V. V. (2015). Mozhlyvosti vplyvu tamsulozynu na retsydyvy u osib z khronichnym prostatytom. Zdorov'e muzhchiny, 2, 84–86.
  7. Gorpinchenko, I. I., Gurzhenko, Yu. N., Nagorniy, A. E. (2014). Opyt primeneniya mnogokomponentnyh fitopreparatov u bol'nyh pri hronicheskom abakterial'nom prostatite / sindrome hronicheskoy tazovoy boli. Zdorov'e muzhchiny, 1, 36–40.
  8. Agbabiaka, T. B., Pitter, M. H., Winder, B., Edzard,E. (2010). Serenoa repens (Saw Palmetto – pal'ma). Sistemniy obzor pobochnyh effektov. Zdorov'e muzhchiny, 1, 33–39.
  9. Gorpinchenko, I. I., Romanyuk, M. G., Aksenov, P. V., Kornienko, A. M. (2015). Svechi Pravenor – novoe slovo v fitoprofilaktike zabolevaniy predstatel'noy zhelezy. Zdorov'e muzhchiny, 3, 65–69.
  10. Komarevcev, V. N., Spiridonenko, V. V., Pepenin, V. R. et. al. (2011). Fitoterapiya i optimizaciya pokazateley kachestva zhizni i dannyh eyakulyata u lic s hronicheskim prostatitom. Zdorov'e muzhchiny, 3, 17–23.
  11. Gorpinchenko, I. I., Gurzhenko, Yu. N., Fedoruk, A. S. et. al. (2011). Nestandartniy fitoterapevticheskiy podhod k lecheniyu hronicheskoy tazovoy boli u muzhchin. Zdorov'e muzhchiny, 4, 57–63.
  12. Bondarenko, V. O., Spivak, Zh. S. (2014). Dosvid zastosuvannia levotyroksynu ta antyoksydantiv pry terapiyi neplidnosti u cholovikiv, khvorykh na hipotyreoz. Mizhnarodnyi endokrynolohichnyi zhurnal, 7, 35–39.
  13. Minuhin, A. S., Bondarenko, V. A. (2014). Kompleksnoe primenenie nekotoryh mikronutrientov u muzhchin s idiopaticheskimi patospermiyami. Zdorov'e muzhchiny, 4, 131–136.
  14. Sarkar, F. H., Li, Y. (2004). Indole-3-Carbinol and Prostate Cancer. The Journal of Nutrition, 134 (12), 3493S–3498S. doi: 10.1093/jn/134.12.3493s
  15. Kalinchenko, S. Yu., Tyuzikov, A. I. (2009). Prakticheskaya andrologiya. Moscow: Prakticheskaya medicina, 299.
  16. Nicastro, H., Dunn, B. (2013). Selenium and Prostate Cancer Prevention: Insights from the Selenium and Vitamin E Cancer Prevention Trial (SELECT). Nutrients, 5 (12), 1122–1148. doi: 10.3390/nu5041122
  17. Cooper, T. G., Noonan, E., von Eckardstein, S., Auger, J., Baker, H. W. G., Behre, H. M. et. al. (2009). World Health Organization reference values for human semen characteristics*‡. Human Reproduction Update, 16 (3), 231–245. doi: 10.1093/humupd/dmp048
  18. Mihaylichenko, V. V.; Tiktinskiy, O. L. (Ed.) (1990). Besplodie u muzhchin. Rukovodstvo po andrologii. Leningrad: Medicina, 297–335.
  19. Gorpinchenko, I. I., Gurzhenko, Yu. N., Dobrovol'skaya, L. I. (2011). Issledovanie vliyaniya preparata Ziman na biohimicheskie pokazateli eyakulyata pri ekskretornom besplodii u muzhchin. Zdorov'e muzhchiny, 1, 160–162.
  20. Gorpinchenko, I. I., Gurzhenko, Yu. N., Kvach, N. D. (2013). Issledovanie effektivnosti ispol'zovaniya preparata Ziman dlya korrekcii metabolizma polovyh gormonov pri lechenii vtorichnogo gipogonadizma u muzhchin. Zdorov'e muzhchiny, 1, 63–67.

Published

2018-02-27

How to Cite

Minukhin, A., Bondarenko, V., & Kononenko, N. (2018). Possibility of using the complex of phytopreparates, vitamins and microelements in the treatment of chronic abacterial prostatitis. ScienceRise: Medical Science, (2 (22), 14–18. https://doi.org/10.15587/2519-4798.2018.124680

Issue

Section

Medical Science