Comparative study of recovery parameters of Desflurane and Sevoflurane in functional endoscopic sinus surgery




functional endoscopic sinus surgeries, desflurane, sevoflurane, general anaesthesia, early recovery, Hemodynamic variables


Numerous inhalant anaesthetics are often utilised to provide the optimal operating field required for successful endoscopic sinus surgery (ESS). Modern inhaled anaesthetics such as Sevoflurane and Desflurane enable rapid induction and recovery because to their low blood-gas partition coefficients.

The aim: The goal of this study is to compare desflurane with sevoflurane's recovery qualities after functional endoscopic sinus surgery.

Materials and methods: The present study was a prospective, randomised, comparative clinical trial that included participants scheduled to have functional endoscopic sinus surgery. The study included 60 ASA I and II patients scheduled for FESS under general anaesthesia and divided them into two groups of 30 each: group D (Desflurane) and group S (Sevoflurane).

Results: There was no statistically significant difference in the age, gender, ASA grade, or mean weight distributions between the two groups (p>0.05). There was no statistically significant difference in the mean length of operation or anaesthesia between the two groups. Hemodynamic variables did not alter much. Time in minutes for eye opening (p<0.001) was significantly shorter in group D (Desflurane) than in group S (Sevoflurane). Time in minutes for extubation (p<0.001) was significantly shorter in group D (Desflurane) 6.53±1.14 than in group S (Sevoflurane) 9.37±1.30. Time in minutes for obeying commands (p<0.001) was significantly shorter in group D (Desflurane) 7.87±1.11 than in group S (Sevoflurane) 11.33±1.51.

Conclusion: In patients receiving FESS time taken for eye opening, extubation and time taken for obeying commands from termination of anesthetic is significantly shorter with desflurane (group D) when compared with sevoflurane (group S). So desflurane was linked to a quicker early recovery than sevoflurane.

Author Biographies

Harish Uppala, Telangana Institute of Medical Sciences

Assistant Professor

Department of Anaesthesiology and Critical Care

Mamidi Ajay Kumar, Telangana Institute of Medical Sciences

Assistant Professor

Department of Anaesthesiology and Critical Care

Mohd Moazzam Mohiuddin Ansari, Telangana Institute of Medical Sciences

Assistant Professor

Department of Anaesthesiology and Critical Care


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How to Cite

Uppala, H., Kumar, M. A., & Ansari, M. M. M. (2022). Comparative study of recovery parameters of Desflurane and Sevoflurane in functional endoscopic sinus surgery. ScienceRise: Medical Science, (2(47), 4–10.



Medical Science