The features of autonomic disorders and ischemic myocardial changes in patients with stable angina pectoris associated with nonalcoholic fatty liver disease

Authors

DOI:

https://doi.org/10.15587/2519-4798.2016.79872

Keywords:

ischemic heart disease, non-alcoholic fatty liver disease, autonomic imbalance, heart rhythm variability

Abstract

The aim of the work was in the establishing of the features of autonomic disorders and ischemic changes of myocardium in patients with stable angina pectoris, associated with non-alcoholic fatty liver disease.

Methods of research: the open prospective cohort study in parallel groups included 54 patients with IHD, among which were 30 patients with non-alcoholic fatty disease of the liver. All patients underwent the general clinical anthropometric examination, daily monitoring of ECG by Holter with determination of myocardium ischemia manifestations, study of the heart rhythm variability using the portable system Cardiosense K. (city Kharkov).

Conclusions: at the stable effort angina, associated with non-alcoholic fatty liver disease, the reliable decrease of SDNNi, RMSSD and pNN50 parameters in active and passive periods and more LF/HF values in both periods are observed that proves the ANS imbalance with predominance of the sympathetic link activity on the background of inhibition of parasympathetic influences. Patients with the stable angina pectoris with NAFLD are characterized with more expressed ischemic changes of myocardium such as prolongation of the general duration of ST segment depression during a day, depth of ST segment depression and the duration of maximal episode of ST segment depression and also the increase of the registration frequency of ventricle extrasystole comparing with patients without NAFLD

Author Biography

Любов Євгеніївна Міняйленко, Zaporizhzhia State Medical University Mayakovskogo ave., 26, Zaporizhzhya, Ukraine, 69035

Department of general practice – family medicine

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Published

2016-10-31

How to Cite

Міняйленко, Л. Є. (2016). The features of autonomic disorders and ischemic myocardial changes in patients with stable angina pectoris associated with nonalcoholic fatty liver disease. ScienceRise: Medical Science, (10 (6), 28–33. https://doi.org/10.15587/2519-4798.2016.79872

Issue

No. 10 (6) (2016)

Section

Medical Science

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Copyright (c) 2016 Любов Євгеніївна Міняйленко

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