Ischemic heart disease and chronic obstructive pulmonary disease: the topical problem of comorbidity in internal medicine

Authors

  • Galina Voinarovska Dmitry F. Chebotarev Institute of Gerontology of National Academy of Medical Sciences of Ukraine Vyshhorodska str., 67, Kyiv, Ukraine, 04114, Ukraine https://orcid.org/0000-0002-1953-0314
  • Ervin Asanov Dmitry F. Chebotarev Institute of Gerontology of National Academy of Medical Sciences of Ukraine Vyshhorodska str., 67, Kyiv, Ukraine, 04114, Ukraine https://orcid.org/0000-0003-4021-1710

DOI:

https://doi.org/10.15587/2519-4798.2020.203968

Keywords:

ischemic heart disease, chronic obstructive pulmonary disease, prevalence, comorbidity, old age

Abstract

The aim. To review the current literature to study the prevalence and early diagnosis of the combined course of ischemic heart disease (IHD) and chronic obstructive pulmonary disease (COPD).

Results. The combination of IHD and COPD is one of the common comorbid conditions, especially in older age. With this mixed pathology, the course of both coronary heart disease and COPD worsens and the risk of adverse events increases. Diagnostic-treatment and rehabilitation programs in combination with coronary heart disease and COPD complication. This requires a comprehensive approach and consideration of the pathogenesis features of each disease. In coronary heart disease, especially in older age, diagnostic measures should include targeted detection of COPD and vice versa.

Conclusions. Despite numerous studies of the IHD-COPD tandem, the issues of prevalence, course, and life expectancy in older patients with this comorbid pathology have not been adequately addressed. Causes of comorbidity are common features of pathogenesis, clinical symptoms and risk factors. At the same time, the combination of coronary heart disease and COPD raises debating questions about diagnosis, treatment and rehabilitation, especially in the elderly and aging. It is in this direction that the focus of future research on the combination of IHD and COPD should be directed. Purposeful study will help to develop directions for correction, prognosis and prevention of this comorbid pathology, especially in elderly patients

Author Biographies

Galina Voinarovska, Dmitry F. Chebotarev Institute of Gerontology of National Academy of Medical Sciences of Ukraine Vyshhorodska str., 67, Kyiv, Ukraine, 04114

Junior Researcher

Department of Clinical Physiology and Pathology of Internal Organs

Ervin Asanov, Dmitry F. Chebotarev Institute of Gerontology of National Academy of Medical Sciences of Ukraine Vyshhorodska str., 67, Kyiv, Ukraine, 04114

MD, Chief Researcher

Department of Clinical Physiology and Pathology of Internal Organs

References

  1. Aisanov, Z. R., Chuchalin, A. G., Kalmanova, E. N. (2019). Chronic obstructive pulmonary disease and cardiovascular comorbidity. Kardiologiia, 59 (8S), 24–36. doi: http://doi.org/10.18087/cardio.2572
  2. Giustina, A., Barkan, A., Beckers, A., Biermasz, N., Biller, B. M. K., Boguszewski, C. et. al. (2019). A Consensus on the Diagnosis and Treatment of Acromegaly Comorbidities: An Update. The Journal of Clinical Endocrinology & Metabolism, 105 (4), e937–e946. doi: http://doi.org/10.1210/clinem/dgz096
  3. Bolotnova, T. V., Okonechnikova, N. S., Andreeva, O. V. et. al. (2016). Klinicheskie osobennosti ishemicheskoi bolezni serdtsa i arterialnoi gipertenzii v usloviiakh komorbidnosti s khronicheskoi obstruktivnoi bolezniu legkikh u bolnykh pozhilogo vozrasta. Meditsinskaia nauka i obrazovanie Urala, 17 (4), 5–9.
  4. Broeiro-Gonçalves, P., Nogueira, P., Aguiar, P. (2019). Multimorbidity and Disease Severity by Age Groups, in Inpatients: Cross-Sectional Study. Portuguese Journal of Public Health, 37 (1), 1–9. doi: http://doi.org/10.1159/000500119
  5. Rakhysheva, A. A., Erdash, B. E., Nurmakhova, Zh. M., Bedelbaeva, G. G. (2014). Difficulties curation of patient with chd and copd. Vestn. KazNMU, 1, 61–64.
  6. Ostroumova, O. D., Kochetkov, A. I. (2018). Chronic obstructive pulmonary disease and comorbid cardiovascular disease: in the context of guidelines. Consilium Medicum, 20 (1), 54–61.
  7. Müllerova, H., Aguti, A., Erqou, S., Mapel, D. W. (2013). Cardiovascular comorbidity in COPD: systematic literature review, 144 (4), 1163‒1178. doi: https://doi.org/10.1378/chest.12-2847
  8. Mostovoi, Yu. M., Slepchenko, N. S., Dmytriiev, K. D., Sydorov, A. A. (2018). Chronic obstructive pulmonary disease and the heart: achievments and current questions. Ukrainskyi pulmonolohichnyi zhurnal, 4, 56–61.
  9. Brandsma, C.-A., de Vries, M., Costa, R., Woldhuis, R. R., Königshoff, M., Timens, W. (2017). Lung ageing and COPD: is there a role for ageing in abnormal tissue repair? European Respiratory Review, 26 (146), 170073. doi: http://doi.org/10.1183/16000617.0073-2017
  10. Finkelstein, J., Cha, E., Scharf, S. (2009). Chronic obstructive pulmonary disease as an independent risk factor for cardiovascular morbidity. International Journal of Chronic Obstructive Pulmonary Disease, 4, 337–349. doi: http://doi.org/10.2147/copd.s6400
  11. Lahousse, L., Niemeijer, M. N., van den Berg, M. E., Rijnbeek, P. R., Joos, G. F., Hofman, A. et. al. (2015). Chronic obstructive pulmonary disease and sudden cardiac death: the Rotterdam study. European Heart Journal, 36 (27), 1754–1761. doi: http://doi.org/10.1093/eurheartj/ehv121
  12. Liu, Y., Narayanan, K., Zhang, Z., Li, G., Liu, T. (2016). Chronic obstructive pulmonary disease and risk of sudden cardiac death. International Journal of Cardiology, 214, 406–407. doi: http://doi.org/10.1016/j.ijcard.2016.03.216
  13. Testa, G., Cacciatore, F., Bianco, A., Della-Morte, D., Mazzella, F., Galizia, G. et. al. (2017). Chronic obstructive pulmonary disease and long-term mortality in elderly subjects with chronic heart failure. Aging Clinical and Experimental Research, 29 (6), 1157–1164. doi: http://doi.org/10.1007/s40520-016-0720-5
  14. Ellingsen, J., Johansson, G., Larsson, K., Lisspers, K., Malinovschi, A., Ställberg, B. et. al. (2020). Impact of Comorbidities and Commonly Used Drugs on Mortality in COPD – Real-World Data from a Primary Care Setting. International Journal of Chronic Obstructive Pulmonary Disease, 15, 235–245. doi: http://doi.org/10.2147/copd.s231296
  15. Saleh, H. Z., Mohan, K., Shaw, M., Al-Rawi, O., Elsayed, H., Walshaw, M. et. al. (2012). Impact of chronic obstructive pulmonary disease severity on surgical outcomes in patients undergoing non-emergent coronary artery bypass grafting. European Journal of Cardio-Thoracic Surgery, 42 (1), 108–113. doi: http://doi.org/10.1093/ejcts/ezr271
  16. Harnek, J., Nilsson, J., Friberg, O., James, S., Lagerqvist, B., Hambraeus, K. et. al. (2013). The 2011 outcome from the Swedish Health Care Registry on Heart Disease (SWEDEHEART). Scandinavian Cardiovascular Journal, 47 (sup62), 1–10. doi: http://doi.org/10.3109/14017431.2013.780389
  17. Andell, P., Koul, S., Martinsson, A., Sundström, J., Jernberg, T., Smith, J. G. et. al. (2014). Impact of chronic obstructive pulmonary disease on morbidity and mortality after myocardial infarction. Open Heart, 1 (1), e000002. doi: http://doi.org/10.1136/openhrt-2013-000002
  18. Yhnatova, H. L., Antonov, V. N., Blynova, E. V. (2019). Vlyianye vozrasta na manyfestatsyiu osnovnыkh klynycheskykh proiavlenyi sochetannoho techenyia khronycheskoi obstruktyvnoi bolezny lehkykh y yshemycheskoi bolezny sertsia. Sovremennye problemy nauky y obrazovanyia, 1. Available at: https://www.science-education.ru/ru/article/view?id=28464
  19. Ignatova, G. L., Antonov, V. N. (2018). Systemic inflammatory markers as predictors of cardiac complications in patients with comorbid course of chronic obstructive pulmonary disease and ischemic heart disease. Consilium Medicum, 20 (11), 40–44. doi: http://doi.org/10.26442/20751753.2018.11.000042
  20. Treumova, S. I., Petrov, S. S., Burmak, Yu. H., Ivanytska, T. A. (2017). Chronic obstructive pulmonary disease and ischemic heart disease: the problems of comorbidity (literature review). Visnyk problem biolohii i medytsyny, 3 (4), 66‒72.
  21. Vatutin, N. T., Smirnova, A. S., Bort, D. V., Taradin, G. G. (2016). Pathogenic particularities of cardiovascular continuum in chronic obstructive pulmonary disease. Russian Pulmonology, 26 (5), 610–617. doi: http://doi.org/10.18093/0869-0189-2016-26-5-610-617
  22. Fushtei, Y. M., Podsevakhyna, S. L., Palamarchuk, A. Y. et. al. (2018). Vlyianye khronycheskoi obstruktyvnoi bolezny lehkykh na klynyko-funktsyonalnoe sostoianye myokarda u bolnыkh yshemycheskoi bolezniu serdtsa. Simeina medytsyna, 1, 73‒76.
  23. Kozyolova, N. A., Masalkyna, O. V., Kozlova, E. V. (2016). Zakonomernosty formyrovanyia khronycheskoi serdechnoi nedostatochnosty u bolnыkh yshemycheskoi bolezniu serdtsa y khronycheskoi obstruktyvnoi bolezniu lehkykh na fone mnozhestvennoi komorbydnoi patolohy. Zhurnal Serdechnaia Nedostatochnost, 17 (3), 151‒163. doi: http://doi.org/10.18087/rhfj.2016.3.2222
  24. Erdmann, E. (2017). Coronary Heart Disease: advances in diagnostics and therapy. DMW – Deutsche Medizinische Wochenschrift, 142 (21), 1565. doi: http://doi.org/10.1055/s-0042-112806
  25. Salam, S., Ghaffar, T., Muhammad, R., Khan, I. (2017). Frequency of undiagnosed chronic obstructive pulmonary disease in patients with coronary artery disease. Journal of Ayub Medical College Abbottabad, 29 (2), 285‒288.
  26. Boschetto, P., Beghé, B., Fabbri, L. M., Ceconi, C. (2012). Link between chronic obstructive pulmonary disease and coronary artery disease: Implication for clinical practice. Respirology, 17 (3), 422–431. doi: http://doi.org/10.1111/j.1440-1843.2011.02118.x
  27. Agrawal, R., Srivastav, A., Ved, M., Gupta, N. (2011). Echocardiographic evaluation of heart in chronic obstructive pulmonary disease patient and its co-relation with the severity of disease. Lung India, 28 (2), 105–109. doi: http://doi.org/10.4103/0970-2113.80321
  28. Rahaghi, F. N., Van Beek, E. J., Washko, G. R. (2014). Cardiopulmonary coupling in chronic obstructive pulmonary disease: the role of imaging. Journal of Thoracic Imaging, 29 (2), 80‒91. doi: http://doi.org/10.1097/rti.0000000000000076
  29. Konecny, T., Somers, K. R., Park, J. Y., John, A., Orban, M., Doshi, R. et. al. (2018). Chronic obstructive pulmonary disease as a risk factor for ventricular arrhythmias independent of left ventricular function. Heart Rhythm, 15 (6), 832–838. doi: http://doi.org/10.1016/j.hrthm.2017.09.042
  30. Erdol, M. A., Ertem, A. G., Demirtas, K., Unal, S., Karanfil, M., Akdi, A. et. al. (2019). Association Between Chronic Obstructive Pulmonary Disease and Coronary Artery Disease Severity. Angiology, 71 (4), 380. doi: http://doi.org/10.1177/0003319719893559
  31. Berliner, D., Schneider, N., Welte, T., Bauersachs, J. (2016). The differential diagnosis of dyspnea. Deutsches Arzteblatt International, 113 (49), 834‒845. doi: http://doi.org/10.3238/arztebl.2016.0834
  32. Odigie-Okon, E., Jordan, B., Dijeh, S. et. al. (2010). Cardiac injury in patients with COPD presenting with dyspnea: a pilot study. International Journal of Chronic Obstructive Pulmonary Disease, 5, 395‒399. doi: http://doi.org/10.2147/copd.s11975
  33. Parshall, M. B., Schwartzstein, R. M., Adams, L., Banzett, R. B., Manning, H. L., Bourbeau, J. et. al. (2012). An Official American Thoracic Society Statement: Update on the Mechanisms, Assessment, and Management of Dyspnea. American Journal of Respiratory and Critical Care Medicine, 185 (4), 435–452. doi: http://doi.org/10.1164/rccm.201111-2042st
  34. Maclay, J. D., MacNee, W. (2013). Cardiovascular Disease in COPD. Chest, 143 (3), 798–807. doi: http://doi.org/10.1378/chest.12-0938
  35. Cavailles, A., Brinchault-Rabin, G., Dixmier, A., Goupil, F., Gut-Gobert, C., Marchand-Adam, S. et. al. (2013). Comorbidities of COPD. European Respiratory Review, 22 (130), 454–475. doi: http://doi.org/10.1183/09059180.00008612
  36. Nussbaumer-Ochsner, Y., Rabe, K. F. (2011). Systemic Manifestations of COPD. Chest, 139 (1), 165–173. doi: http://doi.org/10.1378/chest.10-1252
  37. Demissie, W. R., Tadessa, S., Tegene, E., Mariam, T. G. (2019). Changes on Electrocardiographic Patterns and Associated Factors among Chronic Obstructive Pulmonary Disease Patients. Heart Research – Open Journal, 6 (1), 4–14. doi: http://doi.org/10.17140/hroj-6-149
  38. Sharma, R. A., Hashim, Z., Sharma, E. et. al. (2013). Diagnosis of severity of COPD on the basis of electrocardiogram. Indian Journal of Basic & Applied Medical Research, 2 (6), 527‒530.
  39. Carlin, B. W. (2012). COPD and Associated Comorbidities: A Review of Current Diagnosis and Treatment. Postgraduate Medicine, 124 (4), 225–240. doi: http://doi.org/10.3810/pgm.2012.07.2582
  40. Gooneratne, N. S., Patel, N. P., Corcoran, A. (2010). Chronic Obstructive Pulmonary Disease Diagnosis and Management in Older Adults. Journal of the American Geriatrics Society, 58 (6), 1153–1162. doi: http://doi.org/10.1111/j.1532-5415.2010.02875.x
  41. Blanchette, C. M., Berry, S. R., Lane, S. J. (2011). Advances in chronic obstructive pulmonary disease among older adults. Current Opinion in Pulmonary Medicine, 17 (2), 84–89. doi: http://doi.org/10.1097/mcp.0b013e32834316ff
  42. Incalzi, R. A., Scarlata, S., Pennazza, G., Santonico, M., Pedone, C. (2014). Chronic Obstructive Pulmonary Disease in the elderly. European Journal of Internal Medicine, 25 (4), 320–328. doi: http://doi.org/10.1016/j.ejim.2013.10.001
  43. Sobh, E., Farag, T., Elsawy, S., Fahmy, B. (2018). Evaluation of health-related quality of life in patients with chronic obstructive pulmonary disease. Egyptian Journal of Bronchology, 12 (3), 288–294. doi: http://doi.org/10.4103/ejb.ejb_11_18
  44. Nekrasov, A. A., Timoschenko, E. S., Nekrasov, A. I., Timoschenko, M. V., Klimovich, E. A., Durygina, E. M. (2019). The Effect of Nebivolol on the Prognosis for Patients with a Combination of Coronary Heart Disease and Chronic Obstructive Pulmonary Disease Under the Conditions of 5-year Follow-up. Trudnyi patsient, 17 (3), 6–10.
  45. Global Strategy for the Diagnosis, Management, and prevention of COPD (2020 report). Available at: http://goldcopd.org/wp-content/uploads/2019/11/GOLD-2020-REPORT-ver1.0wms.pdf
  46. Evdokimov, V. V., Evdokimova, A. G., Kovalenko, E. V. et. al. (2019). Effectiveness and safety of bronchodilator use in chronic cardiac insufficiency of ischemic genesis comorbid with chronic obstructive pulmonary disease. Consilium Medicum, 21 (3), 45–51. doi:10.26442/20751753.2019.3.180089
  47. Sessa, M., Mascolo, A., Mortensen, R. N., Andersen, M. P., Rosano, G. M. C., Capuano, A. et. al. (2017). Relationship between heart failure, concurrent chronic obstructive pulmonary disease and beta-blocker use: a Danish nationwide cohort study. European Journal of Heart Failure, 20 (3), 548–556. doi: http://doi.org/10.1002/ejhf.1045

Downloads

Published

2020-05-31

How to Cite

Voinarovska, G., & Asanov, E. (2020). Ischemic heart disease and chronic obstructive pulmonary disease: the topical problem of comorbidity in internal medicine. ScienceRise: Medical Science, (3 (36), 20–24. https://doi.org/10.15587/2519-4798.2020.203968

Issue

No. 3 (36) (2020)

Section

Medical Science

License

Copyright (c) 2020 Galina Voinarovska, Ervin Asanov

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Our journal abides by the Creative Commons CC BY copyright rights and permissions for open access journals.

Authors, who are published in this journal, agree to the following conditions:

1. The authors reserve the right to authorship of the work and pass the first publication right of this work to the journal under the terms of a Creative Commons CC BY, which allows others to freely distribute the published research with the obligatory reference to the authors of the original work and the first publication of the work in this journal.

 2. The authors have the right to conclude separate supplement agreements that relate to non-exclusive work distribution in the form in which it has been published by the journal (for example, to upload the work to the online storage of the journal or publish it as part of a monograph), provided that the reference to the first publication of the work in this journal is included.