Controversial technologies in intramedullary osteosynthesis of rats femur fractures

Authors

DOI:

https://doi.org/10.15587/2519-4798.2021.227854

Keywords:

intramedullary osteosynthesis, nail, osteogenesis, reaming, bone marrow canal, osteoblasts, osteoclasts, resorption

Abstract

The aim: to conduct a comparative study of osteoreparative regeneration, namely in the periosteal and intermediate areas of the cortex, during intramedullary osteosynthesis of the femur of rats with and without reaming of the bone marrow canal.

Materials and methods. The work is based on the results of an experimental study conducted on 56 white mature laboratory rats, which simulated diaphyseal fracture of the femur and performed stable nail osteosynthesis with reaming of the bone marrow canal in the first series and without reaming in the second series of the experiment. Histological examination of the specimens was performed on the 7th, 14th, 28th and 90th day after surgery.

Results. The procedure of reaming the bone marrow canal reduces the potential reparative capacity of bone tissue in the endosteal area and leads to “distorted” activation of the process of the cortex restructuring. There is a significant activation of osteoclastic resorption.

Conclusions. Bone fusion is more active with the use of intramedullary fixator without reaming of the bone marrow canal, because its reaming reduces the manifestations of reparative potentials in the endosteal region and leads to excessive activation of the resorptive process of restructuring the cortex of both endosteal and central part

Author Biographies

Asif Mansyrov, Kharkiv National Medical University

Postgraduate Student

Department of Emergency and Urgent Health Care, Orthopedics and Traumatology

Viktor Lytovchenko , Kharkiv National Medical University

MD, Professor

Department of Emergency and Urgent Health Care, Orthopedics and Traumatology

Yevgeniy Garyachiy , Kharkiv National Medical University

PhD, Assistant

Department of Emergency and Urgent Health Care, Orthopedics and Traumatology

Andriy Lytovchenko , Kharkiv National Medical University

PhD, Assistant

Department of Emergency and Urgent Health Care, Orthopedics and Traumatology

Olena Miroshnichenko, Kharkiv National Medical University

PhD, Professor

Department of Histology, Cytology and Embryology

References

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Published

2021-04-05

How to Cite

Mansyrov, A., Lytovchenko , V., Garyachiy , Y., Lytovchenko , A., & Miroshnichenko, O. . (2021). Controversial technologies in intramedullary osteosynthesis of rats femur fractures. ScienceRise: Medical Science, (2(41), 4–9. https://doi.org/10.15587/2519-4798.2021.227854

Issue

No. 2(41) (2021)

Section

Medical Science

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Copyright (c) 2021 Asif Mansyrov, Viktor Lytovchenko , Yevgeniy Garyachiy , Andriy Lytovchenko , Olena Miroshnichenko

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