Comparative study of recovery parameters of Desflurane and Sevoflurane in functional endoscopic sinus surgery

Authors

DOI:

https://doi.org/10.15587/2519-4798.2022.254084

Keywords:

functional endoscopic sinus surgeries, desflurane, sevoflurane, general anaesthesia, early recovery, Hemodynamic variables

Abstract

Numerous inhalant anaesthetics are often utilised to provide the optimal operating field required for successful endoscopic sinus surgery (ESS). Modern inhaled anaesthetics such as Sevoflurane and Desflurane enable rapid induction and recovery because to their low blood-gas partition coefficients.

The aim: The goal of this study is to compare desflurane with sevoflurane's recovery qualities after functional endoscopic sinus surgery.

Materials and methods: The present study was a prospective, randomised, comparative clinical trial that included participants scheduled to have functional endoscopic sinus surgery. The study included 60 ASA I and II patients scheduled for FESS under general anaesthesia and divided them into two groups of 30 each: group D (Desflurane) and group S (Sevoflurane).

Results: There was no statistically significant difference in the age, gender, ASA grade, or mean weight distributions between the two groups (p>0.05). There was no statistically significant difference in the mean length of operation or anaesthesia between the two groups. Hemodynamic variables did not alter much. Time in minutes for eye opening (p<0.001) was significantly shorter in group D (Desflurane) than in group S (Sevoflurane). Time in minutes for extubation (p<0.001) was significantly shorter in group D (Desflurane) 6.53±1.14 than in group S (Sevoflurane) 9.37±1.30. Time in minutes for obeying commands (p<0.001) was significantly shorter in group D (Desflurane) 7.87±1.11 than in group S (Sevoflurane) 11.33±1.51.

Conclusion: In patients receiving FESS time taken for eye opening, extubation and time taken for obeying commands from termination of anesthetic is significantly shorter with desflurane (group D) when compared with sevoflurane (group S). So desflurane was linked to a quicker early recovery than sevoflurane.

Author Biographies

Harish Uppala, Telangana Institute of Medical Sciences

Assistant Professor

Department of Anaesthesiology and Critical Care

Mamidi Ajay Kumar, Telangana Institute of Medical Sciences

Assistant Professor

Department of Anaesthesiology and Critical Care

Mohd Moazzam Mohiuddin Ansari, Telangana Institute of Medical Sciences

Assistant Professor

Department of Anaesthesiology and Critical Care

References

  1. Siddiqui, B. A., Kim, P. Y. (2022). Anesthesia Stages. StatPearls Treasure Island (FL): StatPearls. Available at: https://www.ncbi.nlm.nih.gov/books/NBK557596/
  2. Winterberg, A. V., Colella, C. L., Weber, K. A., Varughese, A. M. (2018). The Child Induction Behavioral Assessment Tool: A Tool to Facilitate the Electronic Documentation of Behavioral Responses to Anesthesia Inductions. Journal of PeriAnesthesia Nursing, 33 (3), 296–303. doi: http://doi.org/10.1016/j.jopan.2016.10.004
  3. Robertson, S. A., Gogolski, S. M., Pascoe, P., Shafford, H. L., Sager, J., Griffenhagen, G. M. (2018). AAFP Feline Anesthesia Guidelines. Journal of Feline Medicine and Surgery, 20 (7), 602–634. doi: http://doi.org/10.1177/1098612x18781391
  4. Miller, A. L., Theodore, D., Widrich, J. (2022). Inhalational Anesthetic. StatPearls. Treasure Island (FL): StatPearls Publishing. Available at: https://www.ncbi.nlm.nih.gov/books/NBK554540/
  5. Brown, E. N., Pavone, K. J., Naranjo, M. (2018). Multimodal General Anesthesia: Theory and Practice. Anesthesia & Analgesia, 127 (5), 1246–1258. doi: http://doi.org/10.1213/ane.0000000000003668
  6. Scheiermann, P., Herzog, F., Siebenhofer, A., Strametz, R., Weberschock, T. (2018). Intravenous versus inhalational anesthesia for pediatric inpatient surgery – A systematic review and meta-analysis. Journal of Clinical Anesthesia, 49, 19–25. doi: http://doi.org/10.1016/j.jclinane.2018.05.014
  7. Agoliati, A., Dexter, F., Lok, J., Masursky, D., Sarwar, M. F., Stuart, S. B. et. al. (2010). Meta-Analysis of Average and Variability of Time to Extubation Comparing Isoflurane with Desflurane or Isoflurane with Sevoflurane. Anesthesia & Analgesia, 110 (5), 1433–1439. doi: http://doi.org/10.1213/ane.0b013e3181d58052
  8. Iannuzzi, E., Iannuzzi, M., Viola, G., Cerulli, A., Cirillo, V., Chiefari, M. (2005). Desflurane and sevoflurane in elderly patients during general anesthesia: a double blind comparison. Minerva Anestesiol, 71, 147–155. Available at: https://pubmed.ncbi.nlm.nih.gov/15756155/
  9. Magni, G., Rosa, I. L., Melillo, G., Savio, A., Rosa, G. (2009). A Comparison Between Sevoflurane and Desflurane Anesthesia in Patients Undergoing Craniotomy for Supratentorial Intracranial Surgery. Anesthesia & Analgesia, 109 (2), 567–571. doi: http://doi.org/10.1213/ane.0b013e3181ac1265
  10. Erk, G., Erdogan, G., Sahin, F., Taspinar, V., Dikmen, B. (2007). Anesthesia for laparoscopic cholecystectomy: comparative evaluation--desflurane/sevoflurane vs. propofol. Middle East Journal of Anesthesiology, 19 (3), 553–562. Available at: https://pubmed.ncbi.nlm.nih.gov/18044283/
  11. Mahmoud, N. A., Rose, D. J. A., Laurence, A. S. (2001). Desflurane or sevoflurane for gynaecological day-case anaesthesia with spontaneous respiration? Anaesthesia, 56 (2), 171–174. doi: http://doi.org/10.1046/j.1365-2044.2001.01528.x
  12. McKay, R. E., Malhotra, A., Cakmakkaya, O. S., Hall, K. T., McKay, W. R., Apfel, C. C. (2010). Effect of increased body mass index and anaesthetic duration on recovery of protective airway reflexes after sevoflurane vs desflurane. British Journal of Anaesthesia, 104 (2), 175–182. doi: http://doi.org/10.1093/bja/aep374
  13. Pensado Castiñeiras A, Rama Maceiras P, Molins Gauna N, Fiqueira Moure A, VásquezFidalgo A. Immediate anesthesia recovery and psychomotor function of patient after prolonged anesthesia with desflurane, sevoflurane or isoflurane. Rev EspAnestesiolReanim. 2000 Nov;47(9):386-92. https://pubmed.ncbi.nlm.nih.gov/11305138/
  14. Gergin, S., Cevik, B., Yildirim, G. B., Ciplakligil, E. (2005). Colakogul: Sevoflurane Vs Desflurane: Haemodynamic Parameters And Recovery Characteristics. The Internet Journal of Anesthesiology, 9 (1). doi: http://doi.org/10.5580/169
  15. Strum, E. M., Szenohradszki, J., Kaufman, W. A., Anthone, G. J., Manz, I. L., Lumb, P. D. (2004). Emergence and Recovery Characteristics of Desflurane Versus Sevoflurane in Morbidly Obese Adult Surgical Patients: A Prospective, Randomized Study. Anesthesia & Analgesia, 1848–1853. doi: http://doi.org/10.1213/01.ane.0000136472.01079.95
  16. Caverni, V., Rosa, G., Pinto, G., Tordiglione, P., Favaro, R. (2005). Hypotensive Anesthesia and Recovery of Cognitive Function in Long-term Craniofacial Surgery. Journal of Craniofacial Surgery, 16 (4), 531–536. doi: http://doi.org/10.1097/01.scs.0000159084.60049.e6

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Published

2022-03-31

How to Cite

Uppala, H., Kumar, M. A., & Ansari, M. M. M. (2022). Comparative study of recovery parameters of Desflurane and Sevoflurane in functional endoscopic sinus surgery. ScienceRise: Medical Science, (2(47), 4–10. https://doi.org/10.15587/2519-4798.2022.254084

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Section

Medical Science