Singularity of diagnostics of oncopathology in patients in the posttransplantation period

Abstract

The aim of the work was to study the growth of oncopathology in patients in the post-transplant period, the possible cause of which is long-term immunosuppression. Materials and methods. To fulfill this task, we analyzed the literature on the topic of risk of growth of oncopathology and conducted a retrospective analysis in 83 patients after family kidney transplantation aged 18 to 52 years, among which the most interesting case is the case of giant liposarcoma in a patient with 24 years of post-transplant catamnesis. Results and discussion. There are 8 cases of neoplasms in the structure of oncopathology in patients after kidney transplantation. Two cases of skin cancer, one of breast cancer, two of kidney cancer, two of Kaposi’s sarcoma, and one ofgiant liposarcoma. Conclusions. A detailed analysis of patients after kidney transplantation with various nosological forms of kidney damage revealed 8 cases of oncopathology over the past 5 years, which were considered as a possible consequence of long-term immunosuppression. Timely diagnosis of comorbidity syndrome allowed to identify and conduct cytoreductive therapy with the joint participation of specialists in oncology, which allowed to prolong the life of patients with a functioning kidney transplant.