Immunological aspects of cytomegalovirus infection in community-acquired pneumonia among young adults.
DOI:
https://doi.org/10.26641/2307-0404.2018.1(part1).127253Ключевые слова:
community-acquired pneumonia, cytomegalovirus pneumonia, immunosuppression, PORTАннотация
The problem of comorbidities and mutual influence due to progressive immunological suppression occupies an important place in the morbidity structure among young population. This fact is usually considered to be a result of existent immunodeficiency in the process of studying respiratory comorbidities with subsequent chances of immunological reactivities. The purpose of our research is to investigate the features of immunological reactivity changes among young patients with community-acquired pneumonia and cytomegaloviral persistence. Received data showed a high level of cytomegaloviral persistence prevalence which increases the levels of cellular and humor immunodeficiency in patients with community-acquired pneumonia. Such influence on the immunity state is associated with the worse clinical course of CAP according to PORT-scale.
Библиографические ссылки
Pokrovkiy VI, Tvorohova MH, Shypulin HA. [Laboratory diagnostics of infectious diseases]. Publishing house BINOM. 2013;648. Russian.
Melnik AA. [Clinical laboratory tests for practical medicine, their interpritation]. Kyiv, Kniga-plyus. 2011;288. Russian.
Moroz LV, Chichirello-Konstantinovich KD, Konstantynovych TV, Bondarchuk OB. [Characteristics of immunological status of patients with community-acquired pneumonia: the features of cytomegaloviral persistence]. Visnyk Vinnytskoho natsionalnoho medychnoho universytetu. 2015;19(2):423-8. Ukrainian.
Feshchenko YuI, Holubovska OA, Goncharov KA. [Community-acquired and nosocomial pneumonia in adults: etiology, pathogenesis, classification, diagnostics, antibiotic therapy]. Metodychnyi posibnyk. 2014;122. Ukrainian.
Chichirello-Konstantinovich K, Konstantynovych T, Moroz L. Peculiarities of Immune Status among Young Patients with Community-Acquired Pneumonia (CAP) during Cytomegaloviral Persistence (CMVP). European Respiratory Journal. 2017;50(suppl 61):PA987. doi: 10.1183/1393003 PA987
Goussard P, Kling S, Gie R, Nel E, Heyns L, Rossouw G, & Janson J. CMV pneumonia in HIV-infected ventilated infants. Pediatric Pulmonology. 2010;45(7):650-5. http://dx.doi.org/10.1002/ppul.21228
Reeves M, Sinclair J. Aspects of human cytomegalovirus latency and reactivation. Curr. Top. Microbiol. Immunol. 2008;325:297-313.
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