Immunological aspects of cytomegalovirus infection in community-acquired pneumonia among young adults.

Автор(и)

  • K. D. Chichirelo-Konstantynovych
  • L. V. Moroz
  • T. V. Konstantynovych
  • A. V. Demchuk

DOI:

https://doi.org/10.26641/2307-0404.2018.1(part1).127253

Ключові слова:

community-acquired pneumonia, cytomegalovirus pneumonia, immunosuppression, PORT

Анотація

The problem of comorbidities and mutual influence due to progressive immunological suppression occupies an important place in the morbidity structure among young population. This fact is usually considered to be a result of existent immunodeficiency in the process of studying respiratory comorbidities with subsequent chances of immunological reactivities. The purpose of our research is to investigate the features of immunological reactivity changes among young patients with community-acquired pneumonia and cytomegaloviral persistence. Received data showed a high level of cytomegaloviral persistence prevalence which increases the levels of cellular and humor immunodeficiency in patients with community-acquired pneumonia. Such influence on the immunity state is associated with the worse clinical course of CAP according to PORT-scale.

Біографії авторів

K. D. Chichirelo-Konstantynovych

National Pirogov Memorial Medical University, Vinnytsya
Propaedeutics department of internal medicine
Pirogova str., 56, Vinnytsya, 21018, Ukraine

L. V. Moroz

National Pirogov Memorial Medical University, Vinnytsya
Propaedeutics department of internal medicine
Pirogova str., 56, Vinnytsya, 21018, Ukraine

T. V. Konstantynovych

National Pirogov Memorial Medical University, Vinnytsya
Propaedeutics department of internal medicine
Pirogova str., 56, Vinnytsya, 21018, Ukraine

A. V. Demchuk

National Pirogov Memorial Medical University, Vinnytsya
Propaedeutics department of internal medicine
Pirogova str., 56, Vinnytsya, 21018, Ukraine

Посилання

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Moroz LV, Chichirello-Konstantinovich KD, Konstantynovych TV, Bondarchuk OB. [Characteristics of immunological status of patients with community-acquired pneumonia: the features of cytomegaloviral per­sistence]. Visnyk Vinnytskoho natsionalnoho medych­noho universytetu. 2015;19(2):423-8. Ukrainian.

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Chichirello-Konstantinovich K, Konstantyno­vych T, Moroz L. Peculiarities of Immune Status among Young Patients with Community-Acquired Pneumonia (CAP) during Cytomegaloviral Persistence (CMVP). European Res­piratory Journal. 2017;50(suppl 61):PA987. doi: 10.1183/1393003 PA987

Goussard P, Kling S, Gie R, Nel E, Heyns L, Ros­souw G, & Janson J. CMV pneumonia in HIV-infected ven­tilated infants. Pediatric Pulmonology. 2010;45(7):650-5. http://dx.doi.org/10.1002/ppul.21228

Reeves M, Sinclair J. Aspects of human cytome­galovirus latency and reactivation. Curr. Top. Microbiol. Immunol. 2008;325:297-313.

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Як цитувати

1.
Chichirelo-Konstantynovych KD, Moroz LV, Konstantynovych TV, Demchuk AV. Immunological aspects of cytomegalovirus infection in community-acquired pneumonia among young adults. Med. perspekt. [інтернет]. 24, Квітень 2018 [цит. за 27, Липень 2024];23(1(part1):141-5. доступний у: https://journals.uran.ua/index.php/2307-0404/article/view/127253

Номер

Том 23 № 1(part1) (2018)

Розділ

КЛІНІЧНА МЕДИЦИНА

Ліцензія

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