Impact of risk factors in developing bronchial asthma combined with gastroesophageal reflux disease in children

Авторы

  • T.R. Umanets Institute of Pediatrics, Obstetrics and Gynecology named after academician O. Lukyanova of the National Academy of Medical Sciences of Ukraine Maiborоdy str., 8, Kyiv, 04050, Ukraine https://orcid.org/0000-0001-9058-7383
  • A.A. Buratynska Institute of Pediatrics, Obstetrics and Gynecology named after academician O. Lukyanova of the National Academy of Medical Sciences of Ukraine Maiborоdy str., 8, Kyiv, 04050, Ukraine https://orcid.org/0000-0003-3790-0419
  • S.I. Tolkach Institute of Pediatrics, Obstetrics and Gynecology named after academician O. Lukyanova of the National Academy of Medical Sciences of Ukraine Maiborоdy str., 8, Kyiv, 04050, Ukraine https://orcid.org/0000-0002-9508-7932
  • L.S. Stepanova Institute of Pediatrics, Obstetrics and Gynecology named after academician O. Lukyanova of the National Academy of Medical Sciences of Ukraine Maiborоdy str., 8, Kyiv, 04050, Ukraine https://orcid.org/0000-0001-7296-849X
  • S.Yu. Matveeva Institute of Pediatrics, Obstetrics and Gynecology named after academician O. Lukyanova of the National Academy of Medical Sciences of Ukraine Maiborоdy str., 8, Kyiv, 04050, Ukraine https://orcid.org/0000-0002-1725-650X
  • T.V. Kondratenkova Institute of Pediatrics, Obstetrics and Gynecology named after academician O. Lukyanova of the National Academy of Medical Sciences of Ukraine Maiborоdy str., 8, Kyiv, 04050, Ukraine https://orcid.org/0000-0003-0046-4035
  • O.A. Smirnova Institute of Pediatrics, Obstetrics and Gynecology named after academician O. Lukyanova of the National Academy of Medical Sciences of Ukraine Maiborоdy str., 8, Kyiv, 04050, Ukraine https://orcid.org/0000-0002-8338-7161
  • T.A. Garaschenko Institute of Pediatrics, Obstetrics and Gynecology named after academician O. Lukyanova of the National Academy of Medical Sciences of Ukraine Maiborоdy str., 8, Kyiv, 04050, Ukraine https://orcid.org/0000-0002-6086-7795
  • V.F. Lapshyn Institute of Pediatrics, Obstetrics and Gynecology named after academician O. Lukyanova of the National Academy of Medical Sciences of Ukraine Maiborоdy str., 8, Kyiv, 04050, Ukraine https://orcid.org/0000-0003-1896-1865
  • Yu.G. Antipkin Institute of Pediatrics, Obstetrics and Gynecology named after academician O. Lukyanova of the National Academy of Medical Sciences of Ukraine Maiborоdy str., 8, Kyiv, 04050, Ukraine https://orcid.org/0000-0002-8018-4393

DOI:

https://doi.org/10.26641/2307-0404.2020.4.221399

Ключевые слова:

children, asthma, gastroesophageal reflux disease, risk factors

Аннотация

The purpose of the study was to determine the risk factors affecting the development of asthma combined with gastroesophageal reflux disease (GERD). Seventy children aged 5-17 years with asthma were examined. They were divided to two groups: group 1 (50 children with asthma and GERD), and group 2 (20 children with isolated asthma). Medical history data were collected through specially designed questionnaire for parents. It was determined that the perinatal risk factors that likely contributed to developing co-morbid asthma and GERD were a threatened miscarriage (OR=6.65; 95% CI, 1.7-25.6, p=0.003), acute respiratory illnesses during pregnancy (OR=6.52; 95% CI, 1.4-31.2, p=0.008), polyhydramnios (p=0.039) and uterine inertia (p=0.0003). Food hypersensitivity in the first year of life, the severity of asthma in examined children played role in increasing the risk of developing asthma combined with GERD (OR=4.83; 95% CI, 1.3-18.6, p=0.013 and OR=4.45; 95% CI, 1.2-17.1, р=0.019 respectively).

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Опубликован

2020-12-28

Как цитировать

1.
Umanets T, Buratynska A, Tolkach S, Stepanova L, Matveeva S, Kondratenkova T, Smirnova O, Garaschenko T, Lapshyn V, Antipkin Y. Impact of risk factors in developing bronchial asthma combined with gastroesophageal reflux disease in children. Med. perspekt. [Интернет]. 28 декабрь 2020 г. [цитируется по 23 ноябрь 2024 г.];25(4):121-7. доступно на: https://journals.uran.ua/index.php/2307-0404/article/view/221399

Выпуск

Том 25 № 4 (2020)

Раздел

CLINICAL MEDICINE

Лицензия

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