Impact of risk factors in developing bronchial asthma combined with gastroesophageal reflux disease in children

Автор(и)

  • T.R. Umanets Institute of Pediatrics, Obstetrics and Gynecology named after academician O. Lukyanova of the National Academy of Medical Sciences of Ukraine Maiborоdy str., 8, Kyiv, 04050, Україна https://orcid.org/0000-0001-9058-7383
  • A.A. Buratynska Institute of Pediatrics, Obstetrics and Gynecology named after academician O. Lukyanova of the National Academy of Medical Sciences of Ukraine Maiborоdy str., 8, Kyiv, 04050, Україна https://orcid.org/0000-0003-3790-0419
  • S.I. Tolkach Institute of Pediatrics, Obstetrics and Gynecology named after academician O. Lukyanova of the National Academy of Medical Sciences of Ukraine Maiborоdy str., 8, Kyiv, 04050, Україна https://orcid.org/0000-0002-9508-7932
  • L.S. Stepanova Institute of Pediatrics, Obstetrics and Gynecology named after academician O. Lukyanova of the National Academy of Medical Sciences of Ukraine Maiborоdy str., 8, Kyiv, 04050, Україна https://orcid.org/0000-0001-7296-849X
  • S.Yu. Matveeva Institute of Pediatrics, Obstetrics and Gynecology named after academician O. Lukyanova of the National Academy of Medical Sciences of Ukraine Maiborоdy str., 8, Kyiv, 04050, Україна https://orcid.org/0000-0002-1725-650X
  • T.V. Kondratenkova Institute of Pediatrics, Obstetrics and Gynecology named after academician O. Lukyanova of the National Academy of Medical Sciences of Ukraine Maiborоdy str., 8, Kyiv, 04050, Україна https://orcid.org/0000-0003-0046-4035
  • O.A. Smirnova Institute of Pediatrics, Obstetrics and Gynecology named after academician O. Lukyanova of the National Academy of Medical Sciences of Ukraine Maiborоdy str., 8, Kyiv, 04050, Україна https://orcid.org/0000-0002-8338-7161
  • T.A. Garaschenko Institute of Pediatrics, Obstetrics and Gynecology named after academician O. Lukyanova of the National Academy of Medical Sciences of Ukraine Maiborоdy str., 8, Kyiv, 04050, Україна https://orcid.org/0000-0002-6086-7795
  • V.F. Lapshyn Institute of Pediatrics, Obstetrics and Gynecology named after academician O. Lukyanova of the National Academy of Medical Sciences of Ukraine Maiborоdy str., 8, Kyiv, 04050, Україна https://orcid.org/0000-0003-1896-1865
  • Yu.G. Antipkin Institute of Pediatrics, Obstetrics and Gynecology named after academician O. Lukyanova of the National Academy of Medical Sciences of Ukraine Maiborоdy str., 8, Kyiv, 04050, Україна https://orcid.org/0000-0002-8018-4393

DOI:

https://doi.org/10.26641/2307-0404.2020.4.221399

Ключові слова:

children, asthma, gastroesophageal reflux disease, risk factors

Анотація

The purpose of the study was to determine the risk factors affecting the development of asthma combined with gastroesophageal reflux disease (GERD). Seventy children aged 5-17 years with asthma were examined. They were divided to two groups: group 1 (50 children with asthma and GERD), and group 2 (20 children with isolated asthma). Medical history data were collected through specially designed questionnaire for parents. It was determined that the perinatal risk factors that likely contributed to developing co-morbid asthma and GERD were a threatened miscarriage (OR=6.65; 95% CI, 1.7-25.6, p=0.003), acute respiratory illnesses during pregnancy (OR=6.52; 95% CI, 1.4-31.2, p=0.008), polyhydramnios (p=0.039) and uterine inertia (p=0.0003). Food hypersensitivity in the first year of life, the severity of asthma in examined children played role in increasing the risk of developing asthma combined with GERD (OR=4.83; 95% CI, 1.3-18.6, p=0.013 and OR=4.45; 95% CI, 1.2-17.1, р=0.019 respectively).

Посилання

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Опубліковано

2020-12-28

Як цитувати

1.
Umanets T, Buratynska A, Tolkach S, Stepanova L, Matveeva S, Kondratenkova T, Smirnova O, Garaschenko T, Lapshyn V, Antipkin Y. Impact of risk factors in developing bronchial asthma combined with gastroesophageal reflux disease in children. Med. perspekt. [інтернет]. 28, Грудень 2020 [цит. за 23, Листопад 2024];25(4):121-7. доступний у: https://journals.uran.ua/index.php/2307-0404/article/view/221399

Номер

Том 25 № 4 (2020)

Розділ

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