The proteasome activity in pancreas cells under experimental pancreatitis
DOI:
https://doi.org/10.15587/2313-8416.2015.53177Keywords:
proteasome, caspase-like activity, chymotrypsin-like activity, trypsin-like activity, pancreas, pancreatitisAbstract
The caspase-, chymotrypsin- and trypsin-like proteasomal activities in pancreas cells were investigated under the experimental pancreatitis. It has been shown the increase of ATF-independent chymotrypsin-like activity at reduction of trypsin-like and caspase-like activities. At the same time the reduction of trypsin-like activity was due to ATF-dependent hydrolysis, whereas the reduction of caspase-like activity was due to ATF-independent proteolysis
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Copyright (c) 2015 Мария Александровна Тимошенко, Олеся Вадимовна Сокур, Татьяна Владимировна Коваль, Лариса Ивановна Богун
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