The relation of atherosclerotic lesions of BCA against the background of COPD in patients aged 40-60 years. Review of the literature and retrospective analysis
DOI:
https://doi.org/10.15587/2519-4798.2021.246598Keywords:
atherosclerosis, chronic obstructive pulmonary disease, chronic inflammation, matrix metalloproteinases, lipid profile, duplex scanning, sirutinsAbstract
The aim: to determine the possible relationship between chronic obstructive pulmonary disease and the presence of atherosclerosis of the brachiocephalic vessels in persons aged 40–60 years for the possibility of early prevention of cardiovascular events.
Materials and methods: to do this, we reviewed articles using open sources such as PubMED, Medscape and Cochrane library, highlighting the relationship between the development of atherosclerosis and the presence and severity of COPD. Also, based on the University Clinic of ONMedU and Military Clinical Center of the Southern Region, a retrospective analysis of patients with an inconclusively confirmed diagnosis of COPD and conducted biochemical blood tests was carried out in order to study changes in the lipid profile and the presence of BCS in these patients.
Result: In the course of a retrospective analysis of patients, a relationship was found between the presence of BCA atherosclerosis and the presence of COPD, and based on the literature data, a parallel was drawn between changes in the lipid profile in patients with COPD. But, in view of the insufficient number of patients, this topic requires additional research.
Conclusions: thus, based on the obtained data, it can be concluded that there is a connection between the presence of COPD, changes in the lipid profile, and the presence of BCА atherosclerosis. This connection can become one of the key mechanisms of early diagnosis of BCА atherosclerosis
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Copyright (c) 2021 Iryna Andrusyshyna , Viktoria Batashova-Galinska, Tetiana Horbenko, Leonid Kholopov
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