Epidemiology and trend of rabies post exposure prophylaxis at anti rabies clinic of a tertiary care hospital in India

Authors

DOI:

https://doi.org/10.15587/2519-4798.2021.249643

Keywords:

Rabies, Rabies vaccine, Post-exposure prophylaxis, Viralzoonoses

Abstract

Background and Objectives Effective prevention of rabies is possible by vaccination following a rabid animal bite. Objectives of this study was to describe demographics, circumstances of bite and the trend of vaccination over last three years (January 2019-November 2021) in an anti-rabies clinic of a tertiary care hospital.

Materials and Methods This was an observational study of prospective design. All animal bite victims who attended the anti rabies clinic (ARC) of the study institution during the study period were invited to participate in the study. Data was collected using a structured schedule on first visit and at 28th day to check for on time compliance to vaccination schedule. On time completion was defined as taking all vaccine doses on due dates. Distribution of variables was shown by frequencies and percentages. Indicators were recorded for three consecutive years. Year wise indicators were compared by chi-square test.

Results Data was collected for 293 victims. Median age of bite victims was 41.8 years (range 3-78 years) while 58.7 % respondents were below 45 years of age; 71.3 % victims were male. 82.3 % bites were by dogs; 38 % victims had multiple bites. Post-exposure prophylaxis (PEP) with anti-rabies vaccine (ARV) was initiated within 72 hours for 80 % victims and it was completed on time for 66.2 % victims. Three years trend for PEP indicators did not show a statistically significant difference.

Conclusion On time PEP schedule completion was fairly high at the studied ARC. Health seeking for PEP following animal bite was not affected by the corona virus pandemic

Author Biography

Mousumi Datta, Medical College Kolkata

MD

Department of Community Medicine

References

  1. Rabies. World Health Organisation. Available at: https://www.who.int/health-topics/rabies#tab=tab_1
  2. Neglected Tropical Diseases. World Health Organisation. Available at: https://www.who.int/teams/control-of-neglected-tropical-diseases/rabies/epidemiology-and-burden
  3. Abela-Ridder, B. (Ed.) (2020). United against rabies forum: zero by 30, one health in action. World Health Organisation, 13. Available at: https://www.who.int/publications/i/item/WHO-UCN-NTD-VVE-2021.1
  4. Harris, R. C., Chen, Y., Côte, P., Ardillon, A., Nievera, M. C., Ong-Lim, A. et. al. (2021). Impact of COVID-19 on routine immunisation in South-East Asia and Western Pacific: Disruptions and solutions. The Lancet Regional Health – Western Pacific, 10. doi: http://doi.org/10.1016/j.lanwpc.2021.100140
  5. Overview of the COVID-19 situation in Gavi-supported countries and Gavi’s response (2020). Gavi. Available at: https://www.gavi.org/vaccineswork/16-june-2020-overview-covid-19-situation-gavi-supported-countries-and-gavis Last accessed: 05.12.2020
  6. Lassi, Z. S., Naseem, R., Salam, R. A., Siddiqui, F., Das, J. K. (2021). The Impact of the COVID-19 Pandemic on Immunization Campaigns and Programs: A Systematic Review. International Journal of Environmental Research and Public Health, 18 (3), 988. doi: http://doi.org/10.3390/ijerph18030988
  7. Mahendra, B. J., Harish, B. R., Vinay, M. (2009). A study of factors influencing compliance to IDRV at anti-rabies clinic of Mandya Institute of Medical Sciences, Mandya. APCRI Journal, 11, 18–20.
  8. Jesha, M., Martin, J., Bina, T., Raphel, L., Lailabi, Jayadev (2011). Compliance to IDRV at the anti rabies clinic in a tertiary care hospital in North Kerala. APCRI Journal, 12, 21–14.
  9. WHO Weekly Epidemiological record. Rabies position paper. Available at: https://apps.who.int/rabies/resources/weekly_epidemiological_record/en/index.html
  10. Anandaraj, R., Balu, S. P. (2016). Compliance to anti rabies vaccine and animal bite management practices in a rural area of Davangere, Karnataka, India. International Journal of Community Medicine and Public Health, 3 (1), 170–173. doi: http://doi.org/10.18203/2394-6040.ijcmph20151556
  11. Amrutha, A. M., Naveen, K. H., Sushma, J. (2017). Profile of animal bite cases attending anti-rabies clinic of a tertiary care hospital in Mysore and their compliance to 4-dose intradermal rabies vaccine. Annals of Community Health, 5 (4), 2–5.
  12. Jahnavi, R., Vinay, M., Manuja, L. M., Harish, B. R. (2015). Profile of patients attending anti rabies clinic in a government tertiary care hospital in South Karnataka and their compliance to 4-dose intradermal rabies vaccine. APCRI Journal, 17, 16–19.
  13. WHO fact sheet on rabies. World Health Organisation. Available at http://www.who.int/mediacentre/factsheets/fs099/en/
  14. Fevre, E. M., Kaboyo, R. W., Persson, V., Edelsten, M., Coleman, P. G., Cleaveland, S. (2005). The epidemiology of animal bite injuries in Uganda and projections of the burden of rabies. Tropical Medicine and International Health, 10 (8), 790–798. doi: http://doi.org/10.1111/j.1365-3156.2005.01447.x
  15. New WHO recommendations on human rabies immunization and results of GAVI’s Learning Agenda on rabies & 2nd international meeting of the Pan-African Rabies Control Network (PARACON) Meeting Report (2018). Johannesburg: World Health Organisation. Available at: https://www.who.int/health-topics/rabies
  16. Wilde, H. (2007). Failures of post-exposure rabies prophylaxis. Vaccine, 25 (44), 7605–7609. doi: http://doi.org/10.1016/j.vaccine.2007.08.054
  17. Warrell, M. J. (2012). Current rabies vaccines and prophylaxis schedules: Preventing rabies before and after exposure. Travel Medicine and Infectious Disease, 10 (1), 1–15. doi: http://doi.org/10.1016/j.tmaid.2011.12.005
  18. Standard Reports/11~G. RCH Reports – Indicator Wise/2~Immunisation. Ministry of Health and Family Welfare, Government of India. Available at: https://hmis.nhp.gov.in/#!/standardReports
  19. Whaley, C. M., Pera, M. F., Cantor, J., Chang, J., Velasco, J., Hagg, H. K. et. al. (2020). Changes in Health Services Use Among Commercially Insured US Populations During the COVID-19 Pandemic. JAMA Network Open, 3 (11). doi: http://doi.org/10.1001/jamanetworkopen.2020.24984
  20. Rana, M. S., Jahan, A. A., Kaisar, S. M. G., Siddiqi, U. R., Sarker, S., Begum, M. I. A. et. al. (2021). Knowledge, attitudes and perceptions about rabies among the people in the community, healthcare professionals and veterinary practitioners in Bangladesh. One Health, 13. doi: http://doi.org/10.1016/j.onehlt.2021.100308

Downloads

Published

2021-11-30

How to Cite

Datta, M. (2021). Epidemiology and trend of rabies post exposure prophylaxis at anti rabies clinic of a tertiary care hospital in India. ScienceRise: Medical Science, (6(45), 20–24. https://doi.org/10.15587/2519-4798.2021.249643

Issue

Section

Medical Science