Morpho-functional state of the heart and pulmonary artery pressure in elderly hypertesives with atriall fibrillation
DOI:
https://doi.org/10.15587/2519-4798.2016.74197Keywords:
hypertension, atrial fibrillation older age, diastolic dysfunction, pulmonary hypertensionAbstract
The aim: To carry out a comparative study of the structural and functional state of the heart in patients with essential hypertension (EH) depending on the form of atrial fibrillation (AF) - persistent or permanent
Methods: Doppler echocardiography, EHRA scale and CHA2DS2VASc. 95 patients aged 60-74 were included in the study, 20 of which with uncomplicated essential hypertension (EH), 39 – with persistent (PersAF) and 36 – permanent (PermAF) atrial fibrillation (AF).
Results: as compared with uncomplicated EH, the increase in a degree of left ventricular hypertrophy (LVH) and left atrial size (LA) was found out to be a marker of a diastolic dysfunction of the left ventricle (LV) in AF patients. The highest values of LVH and LA were registered in PermAF. The characteristic PermAF heart rate acceleration appeared to be a significant factor of the heart structure and function changes, notably the increase of LVH and LA dilatation. LV systolic function demonstrated the deterioration in PermAF: along with reduces LV ejection fraction there were 10 % patients with systolic dysfunction. In the majority of AF patients pulmonary hypertension was found: I stage – 51 % in PersAF and 67 % in PermAF; II stage in 5 % and 14 %, respectively. The increase in systolic blood pressure in the pulmonary artery in AF is associated with an increase of right ventricle.
Conclusions: Patients with AF have had more apparent structural and functional state of the heart. OP GB further contributes to the disturbance of systolic and diastolic LV function in patients. The increase in diastolic LV dysfunction is associated with increased pressure in the pulmonary artery.References
- Baranova, E. I. (2011). Atrial fibrillation in hypertensive patients. Arterial Hypertension, 17 (4), 293–304.
- Lewington S., Clarke R., Qizilbash N., Peto R., Collins R. (2002). Prospective Studies Collaboration. Age-specific relevance of usual blood pressure to vascular mortality: a meta-analysis of individual data for one million adults in 61 prospective studies. Lancet, 360 (9349), 1903–1913. doi: 10.1016/s0140-6736(02)11911-8
- Kannel, W. B., Wolf, P. A., Benjamin, E. J., Levy, D. (1998). Prevalence, incidence, prognosis, and predisposing conditions for atrial fibrillation: population-based estimates. The American Journal of Cardiology, 82 (7), 2N–9N. doi: 10.1016/s0002-9149(98)00583-9
- Rosenberg, M. A., Gottdiener, J. S., Heckbert, S. R., Mukamal, K. J. (2011). Echocardiographic diastolic parameters and risk of atrial fibrillation: the Cardiovascular Health Study. European Heart Journal, 33 (7), 904–912. doi: 10.1093/eurheartj/ehr378
- Filatov, A. G., Tarashvili, E. G. (2012). Epidemiology and social significance of the atrial fibrillation. Ann. aritmol., 5–13.
- Zholbaeva, A. Z., Tabina, A. E., Goluhova, E. Z. (2015). Molekulyarnye mekhanizmy fibrillyacii predserdij: v poiske «ideal’nogo» markera. Kreativnaya kardiologiya, 2, 40–53.
- January, C. T., Wann, L. S., Alpert, J. S., Calkins, H., Cigarroa, J. E., Cleveland, J. C. et. al. (2014). 2014 AHA/ACC/HRS Guideline for the Management of Patients With Atrial Fibrillation: Executive Summary: A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and the Heart Rhythm Society. Circulation, 130 (23), 2071–2104. doi: 10.1161/cir.0000000000000040
- Waggoner, A. D., Bierig, S. M. (2001). Tissue Doppler imaging: A useful echocardiographic method for the cardiac sonographer to assess systolic and diastolic ventricular function. Journal of the American Society of Echocardiography, 14 (12), 1143–1152. doi: 10.1067/mje.2001.115391
- Galderisi, M., Henein, M. Y., D’hooge, J., Sicari, R., Badano, L. P., Zamorano, J. L., Roelandt, J. R. T. C. (2011). Recommendations of the European Association of Echocardiography How to use echo-Doppler in clinical trials: different modalities for different purposes. European Journal of Echocardiography, 12 (5), 339–353. doi: 10.1093/ejechocard/jer051
- Nagueh, S. F., Appleton, C. P., Gillebert, T. C., Marino, P. N., Oh, J. K., Smiseth, O. A. et. al. (2008). Recommendations for the Evaluation of Left Ventricular Diastolic Function by Echocardiography. European Journal of Echocardiography, 10 (2), 165–193. doi: 10.1093/ejechocard/jep007
- Rakowski, H., Appleton, C., Chan, K.-L., Dumesni, J. G., Honos, G., Jue, J. et. al. (1996). Canadian consensus recommendations for the measurement and reporting of diastolic dysfunction by echocardiography. Journal of the American Society of Echocardiography, 9 (5), 736–760. doi: 10.1016/s0894-7317(96)90076-0
- Go, O., Rosendorff, C. (2009). Hypertension and atrial fibrillation. Current Cardiology Reports, 11 (6), 430–435. doi: 10.1007/s11886-009-0062-4
- Aldhoon, B., Melenovsky, V., Peichl, P., Kautzner, J. (2010). New insights into mechanisms of atrial fibrillation. Physiol. Res., 59 (1), 1–12.
- Nagueh, S. F., Appleton, C. P., Gillebert, T. C., Marino, P. N., Oh, J. K., Smiseth, O. A. et. al. (2009). Recommendations for the Evaluation of Left Ventricular Diastolic Function by Echocardiography. Journal of the American Society of Echocardiography, 22 (2), 107–133. doi: 10.1016/j.echo.2008.11.023
- Mitchell, G. F., Vasan, R. S., Keyes, M. J., Parise, H., Wang, T. J., Larson, M. G. et. al. (2007). Pulse Pressure and Risk of New-Onset Atrial Fibrillation. JAMA, 297 (7), 709–715. doi: 10.1001/jama.297.7.709
- Benjamin, E. J. (1994). Independent Risk Factors for Atrial Fibrillation in a Population-Based Cohort. JAMA, 271 (11), 840–844. doi: 10.1001/jama.1994.03510350050036
- Houmsse, M., Tyler, J., Kalbfleisch, S. (2011). Supraventricular tachycardia causing heart failure. Current Opinion in Cardiology, 26 (3), 261–269. doi: 10.1097/hco.0b013e328345b010
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2016 Любовь Владимировна Бевзюк
This work is licensed under a Creative Commons Attribution 4.0 International License.
Our journal abides by the Creative Commons CC BY copyright rights and permissions for open access journals.
Authors, who are published in this journal, agree to the following conditions:
1. The authors reserve the right to authorship of the work and pass the first publication right of this work to the journal under the terms of a Creative Commons CC BY, which allows others to freely distribute the published research with the obligatory reference to the authors of the original work and the first publication of the work in this journal.
2. The authors have the right to conclude separate supplement agreements that relate to non-exclusive work distribution in the form in which it has been published by the journal (for example, to upload the work to the online storage of the journal or publish it as part of a monograph), provided that the reference to the first publication of the work in this journal is included.