Condition of platelet homeostasis in patients with hypertension and its combination with ischemic heart disease

Authors

DOI:

https://doi.org/10.15587/2519-4798.2016.74326

Keywords:

hypertension, ischemic heart disease, hemostasis, spontaneous aggregation, induced aggregation

Abstract

Aim of the work is in assessment of spontaneous and induced aggregation in patients with hypertension and revelation of features of aggregative activity of platelets at combination of hypertension with ischemic heart disease.

Methods of research: special laboratory studies: spontaneous aggregation of platelets with arachidonic acid, adenosine diphosphate, collagen and adrenalin.

Results of research: in the result of the work was revealed the high level of spontaneous aggregation of platelets in both studied groups. It was established, that associated course of hypertension and IHD is attended by preservation of the sufficiently high functional activity of platelets despite the antiplatelet treatment that is typical for patients with hypertension of both II and III stages. Platelets of patients with hypertension of III stage with concomitant IHD even under conditions of aggressive antiplatelet treatment stay more reactive that is manifested in preservation of the high level of spontaneous aggregation and adrenalin-induced aggregation in subgroup of patients who do not receive ß-adrenoblockers

Author Biography

Анна Ігорівна Пастушина, National Medical University Bogomolets Shevchenko blvd., 13, Kyiv, Ukraine, 01601

Department of Internal Medicine propaedeutics № 1 

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Published

2016-07-30

How to Cite

Пастушина, А. І. (2016). Condition of platelet homeostasis in patients with hypertension and its combination with ischemic heart disease. ScienceRise: Medical Science, (7 (3), 29–33. https://doi.org/10.15587/2519-4798.2016.74326

Issue

No. 7 (3) (2016)

Section

Medical Science

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Copyright (c) 2016 Анна Ігорівна Пастушина

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