Developing the design of triturate tablet machine

Authors

  • Владислав Юрійович Шибецький National Technical University of Ukraine "Kyiv Polytechnic Institute" Pobedy, 37, Kyiv, Ukraine, 03056, Ukraine https://orcid.org/0000-0001-5482-0838
  • Вадим Миколайович Поводзинський National Technical University of Ukraine "Kyiv Polytechnic Institute" Pobedy, 37, Kyiv, Ukraine, 03056, Ukraine https://orcid.org/0000-0002-9591-909X

DOI:

https://doi.org/10.15587/2312-8372.2014.25303

Keywords:

medicine, triturate tablets, tablet machine, liophilicity, wet granulation

Abstract

Producing medicines that meet the requirements of current legislation requires equipment that is designed, operated and repaired under conditions of Good manufacturing practice. For implementing this prerequisite, correct formulation of source data and technical design specification is needed.

Producing solid dosage forms is realized in a typical technological process, where wet granulation and drying of the obtained molding compound is a significant part of production. Creating tablet machine for producing molded (triturate) tablets needs taking into account the specificity of the finished products and improving the technological process at combining several operations. In this paper, modern concept of technical specification in designing triturate tablet machine and its design, which takes into account achievements in pharmaceutical engineering and provides even distribution of ingredients, sterility and liophilicity are developed. The design of the developed triturate tablet machine allows significantly change the concept of producing molded tablets and creates modern principles in the wider use of this type of solid forms for technologies of sterile and non-sterile medicines.

Author Biographies

Владислав Юрійович Шибецький, National Technical University of Ukraine "Kyiv Polytechnic Institute" Pobedy, 37, Kyiv, Ukraine, 03056

Assistant of the department of biotechnology and engineering

Вадим Миколайович Поводзинський, National Technical University of Ukraine "Kyiv Polytechnic Institute" Pobedy, 37, Kyiv, Ukraine, 03056

Ph.D., Associate Professor

Department of Bioengineering and Engineering

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Published

2014-06-24

How to Cite

Шибецький, В. Ю., & Поводзинський, В. М. (2014). Developing the design of triturate tablet machine. Technology Audit and Production Reserves, 3(4(17), 4–8. https://doi.org/10.15587/2312-8372.2014.25303

Issue

Vol. 3 No. 4(17) (2014): Production reserves

Section

Production reserves

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Copyright (c) 2016 Владислав Юрійович Шибецький, Вадим Миколайович Поводзинський

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