Pathophysiology of the excretory system in case of general unintentional overheating of the body (scientific and literary review)




thermal damage, general hypеrthermia of the body, acute kidney injury


Due to the global warming of the climate, unintentional general overheating of the body is a certain problem among the military, workers of "hot enterprises", agricultural workers, etc. With heat stress, acute kidney damage is caused in 25-35% of cases, and with heat stroke it exceeds 50% and requires renal replacement therapy and is accompanied by significant mortality. Chronic or repeated episodes of heat stress with dehydration ultimately lead to abnormal repair mechanisms, renal fibrosis, urolithiasis, vascular refinement, and glomerulosclerosis. The authors hope that the collected material will be useful for medical workers to help victims of accidental general overheating.


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