Analysis of the Practice of Key Actors in the European Union Risk Assessment of the Influence of Chemical Substances On the Environment and Human Health on the Background of Modern Interactive Development
Keywords:
risk assessment, environmental management system, MERLIN-Expo, chemicals, environment, health man,Abstract
Purpose. An analysis of the peculiarities of the main management actors for the risk assessment due to exposure to chemicals on the environment and human health.. Methods. Theoretical analysis and synthesis. Results. There are presented the analysis of the functioning of the major European Union relating to the regulation of normative principles of risk assessment, due to the impact of chemicals on the environment and public health. Thus were revealed major issues, the solution of which requires the latest developments, which would include a comprehensive approach. One of these modern developments have MERLIN-Expo, the main advantages of this tool are presented in this article. Conclusions. There is a need to develop a new comprehensive software, modular design which would allow to assess the impact of complex dynamic systems that evolve over time. MERLIN-Expo covers the entire chain of exposure assessment, which is the most "weak" place in the overall risk assessment.
References
Ciffroy P.,Alfonso B., Altenpohl A. Modelling the exposure to chemicals for risk assessment: a comprehensive library of multimedia and PBPK models for integration, prediction, uncertainty and sensitivity analysis - the MERLIN-Expo tool. // Sci Total Environ.2016.–URL: https://www.ncbi.nlm.nih.gov/pubmed/27169730.
Deliverable D5.2: Report on case study 2. - 4-FUN project: 2015 – URL: http://4funproject.eu/
Fierens T., Van Holderbeke M.Multimedia & PBPK modelling with MERLIN-Expo versus biomonitoring for assessing Pb exposure of pre-school children in a residential setting. // Sci Total Environ.. – 2016. – URL:https://www.ncbi.nlm.nih.gov/ pub-med/27102273.
Final Report Summary - 4FUN (The FUture of FUlly integrated human exposure assessment of chemicals: Ensuring the long-term viability and technology transfer of the EU-FUNded 2-FUN tools as standardised solution). 2016 – URL: http://cordis.europa.eu/result/rcn/182458_en.html
Official website of the European Union. 2016 – URL: https://europa.eu
Overview of the MERLIN-Expo tool. 2016 [Електронний ресурс] – URL: http://merlin-expo.eu/
Radomyski A., Giubilato E., Ciffroy P. Modelling ecological and human exposure to POPs in Venice lagoon – Part II: Quantitative uncertainty and sensitivity analysis in coupled exposure models [Електронний ресурс]// Science of The Total Environment. – 2016. – URL: http://www.sciencedirect.com/science/article/pii/S0048969716315029.
Registration Evaluation Authorisation and restriction of Chemicals (REACH) Regulation (EC 1907/2006) REACH Definitions and REACH – URL:http://www.reach-com pli ance.eu/english/ REACHME/engine/sources/definitions.htm
Report of the verification of models. – 4-FUN project: 2015 – URL: http://4funproject.eu/
The Future of Environmental and Human Health Exposure Modelling of Chemicals. - online course. 2016 – URL: http://e-learning.opentea.eu/
Про основні засади (стратегію) державної екологічної політики України на період до 2020 року: Закон України від 21 груд. 2010 р. № 2818-VI. – URL: http:// zakon2.rada.gov.ua
Угода про асоціацію між Україною та Європейським Союзом / Уряд. Портал – URL : http://www.kmu.gov.ua/control/ publish/article? art_id=246581344
Downloads
Issue
Section
License
Authors reserve the right of attribution for the submitted manuscript, while transferring to the Journal the right to publish the article under the Creative Commons Attribution License. This license allows free distribution of the published work under the condition of proper attribution of the original authors and the initial publication source (i.e. the Journal)Authors have the right to enter into separate agreements for additional non-exclusive distribution of the work in the form it was published in the Journal (such as publishing the article on the institutional website or as a part of a monograph), provided the original publication in this Journal is properly referenced
The Journal allows and encourages online publication of the manuscripts (such as on personal web pages), even when such a manuscript is still under editorial consideration, since it allows for a productive scientific discussion and better citation dynamics (see The Effect of Open Access).