Tsong-Long Hwang

Chang Gung University, Taiwan, Province of China
Professor, College of Medicine

Scopus profile: link
Researcher ID: AAE-6944-2020
ID ORCID: http://orcid.org/0000-0002-5780-3977

Professional (scientific) interests: neutrophilic inflammation, innate immunity, signal transduction, protein kinase, drug research and development

Selected Publications:

  1. Hung, C.-L., Huang, L.-C., Shih, K.-Y., Lai, K.-H., Peng, B.-R., Hwang, T.-L., Chien, S.-Y., Li, C.-Y., Chung, H.-M. (2024). A new sterol from the Formosan soft coral Lobophytum durum. Journal of Molecular Structure, 1296, 136790. doi: https://doi.org/10.1016/j.molstruc.2023.136790

  2. Wang, H.-L., Cheng, Y.-C., Yeh, T.-H., Liu, H.-F., Weng, Y.-H., Chen, R.-S., Chen, Y.-C., Lu, J.-C., Hwang, T.-L., Wei, K.-C., Liu, Y.-C., Wang, Y.-T., Hsu, C.-C., Chiu, T.-J., Chiu, C.-C. (2023). HCH6-1, an antagonist of formyl peptide receptor-1, exerts anti-neuroinflammatory and neuroprotective effects in cellular and animal models of Parkinson’s disease. Biochemical Pharmacology, 212, 115524. doi: https://doi.org/10.1016/j.bcp.2023.115524

  3. Kung, T.-A., Chen, L.-Y., Li, C.-Y., Peng, B.-R., Hwang, T.-L., Sung, P.-J., Lai, K.-H., Chung, H.-M. (2023). Anti-inflammatory cembrane-based diterpenoids isolated from the octocoral Sinularia querciformis. Phytochemistry Letters, 55, 12–16. doi: https://doi.org/10.1016/j.phytol.2023.03.004

  4. Tsai, Y.-F., Yang, S.-C., Hsu, Y.-H., Chen, C.-Y., Chen, P.-J., Syu, Y.-T., Lin, C.-H., Hwang, T.-L. (2023). Carnosic acid inhibits reactive oxygen species-dependent neutrophil extracellular trap formation and ameliorates acute respiratory distress syndrome. Life Sciences, 321, 121334. doi: https://doi.org/10.1016/j.lfs.2022.121334

  5. Ke, T.-Y., Wang, S.-W., Chen, S.-R., Huang, D.-M., Lin, Y.-S., Hwang, T.-L., Sun, W.-C., Cheng, Y.-B. (2023). Alkaloids and Polyacetylenes from Hippobroma longiflora with Antiangiogenesis Properties. Journal of Natural Products, 86 (4), 719–729. doi: https://doi.org/10.1021/acs.jnatprod.2c00853

  6. El-Gamil, D. S., ElHady, A. K., Chen, P.-J., Hwang, T.-L., Abadi, A. H., Abdel-Halim, M., Engel, M. (2023). Discovery of novel 5-methoxybenzothiophene hydrazides as metabolically stable Clk1 inhibitors with high potency and unprecedented Clk1 isoenzyme selectivity. European Journal of Medicinal Chemistry, 247, 115019. doi: https://doi.org/10.1016/j.ejmech.2022.115019

  7. Chen, Y.-L., Chen, C.-Y., Lai, K.-H., Chang, Y.-C., Hwang, T.-L. (2023). Anti-inflammatory and antiviral activities of flavone C-glycosides of Lophatherum gracile for COVID-19. Journal of Functional Foods, 101, 105407. doi: https://doi.org/10.1016/j.jff.2023.105407