Liudas P. Ivanauskas

Lithuanian University of Health Science, Lithuania
Doctor of Biomedical Sciences, Professor, Head of the Department of Analytical and Toxicological Chemistry

Scopus profile: link
ID ORCID: https://orcid.org/0000-0001-5390-2161



Professional (scientific) interests: the scientific work area involves investigations into the chemical composition of plant origin raw materials and herbal preparations. The area of research covers development, optimisation and application of HPLC methods. New modern informative analysis methods characterised by high selectivity and informational capability are being developed and validated for the chemical evaluation of the groups of biologically active compounds in raw materials of plant origin (The raw material of ginkgo, ginseng, St. John's wort, blueberry, goldenrod, ginkgo, ginseng, oregano, thyme, potatoes, buckwheat, bee products were analyzed). HPLC post-column assays are developed and optimised. Besides, the scientific research on optimisation of equipment complementation and system constitution for the screening of various antioxidants of plant origin, for the evaluation of their distribution in different plant organs, and for quality control by antioxidant activity is performed. DPPH and ABTS post-column assays are optimised for the rapid identification and activity determination of antioxidants in complex mixtures after the chromatographical separation of analytes. The reseach evaluating antioxidant activity of phenolic compounds in the extracts of herbal raw materials is conducted as well.

Selected Publications:

  1. Maslii, Y., Herbina, N., Dene, L., Ivanauskas, L., Bernatoniene, J. (2024). Development and Evaluation of Oromucosal Spray Formulation Containing Plant-Derived Compounds for the Treatment of Infectious and Inflammatory Diseases of the Oral Cavity. Polymers, 16 (18), 2649. https://doi.org/10.3390/polym16182649

  2. Griskeviciene, U., Dambrauskiene, J., Marksa, M., Mazeliene, Z., Vainoriene, R., Ivanauskas, L. (2024). Effect of the Phenological Stage on the Phenolic Composition, and Antioxidant and Antimicrobial Properties of Cirsium vulgare (Savi) Ten. Extracts. Life, 14 (9), 1191. https://doi.org/10.3390/life14091191

  3. Mykhailenko, O., Hurina, V., Ivanauskas, L., Marksa, M., Skybitska, M., Kovalenko, O., Lytkin, D., Vladymyrova, I., Georgiyants, V. (2024). Lavandula angustifolia Herb from Ukraine: Comparative Chemical Profile and in vitro Antioxidant Activity. Chemistry & Biodiversity, 21 (9). https://doi.org/10.1002/cbdv.202400640

  4. Kovregin, O., Lytkin, D., Mykhailenko, O., Ivanauskas, L., Yudkevych, T., Vladymyrova, I., Khodak, L., Starikov, V. (2024). Study of phenolic compounds of umbellate wintergreen herb and their influence on biochemical indicators of blood and urine in the rat model of chronic kidney disease. ScienceRise: Pharmaceutical Science, 4 (50), 44–52. https://doi.org/10.15587/2519-4852.2024.310744

  5. Svetikiene, D., Zamokas, G., Jokubaite, M., Marksa, M., Ivanauskas, L., Babickaite, L., Ramanauskiene, K. (2024). The Comparative Study of the Antioxidant and Antibacterial Effects of Propolis Extracts in Veterinary Medicine. Veterinary Sciences, 11 (8), 375. https://doi.org/10.3390/vetsci11080375

  6. Slavinskienė, G., Grigonis, A., Ivaškienė, M., Sinkevičienė, I., Andrulevičiūtė, V., Ivanauskas, L., Juodžentė, D., Ramanauskienė, K., Daunoras, G. (2024). A Comparative Study of the Chemical Properties and Antibacterial Activity of Four Different Ozonated Oils for Veterinary Purposes. Veterinary Sciences, 11 (4), 161. https://doi.org/10.3390/vetsci11040161

  7. Ivanauskas, L., Uminska, K., Gudžinskas, Z., Heinrich, M., Georgiyants, V., Kozurak, A., Mykhailenko, O. (2023). Phenological Variations in the Content of Polyphenols and Triterpenoids in Epilobium angustifolium Herb Originating from Ukraine. Plants, 13 (1), 120. https://doi.org/10.3390/plants13010120