Liudas P. Ivanauskas

Lithuanian University of Health Science, Lithuania
Doctor of Biomedical Sciences, Professor, Head of the Department of Analytical and Toxicological Chemistry

Scopus profile: link
Researcher ID: DYF-6111-2022



Professional (scientific) interests: the scientific work area involves investigations into the chemical composition of plant origin raw materials and herbal preparations. The area of research covers development, optimisation and application of HPLC methods. New modern informative analysis methods characterised by high selectivity and informational capability are being developed and validated for the chemical evaluation of the groups of biologically active compounds in raw materials of plant origin (The raw material of ginkgo, ginseng, St. John's wort, blueberry, goldenrod, ginkgo, ginseng, oregano, thyme, potatoes, buckwheat, bee products were analyzed). HPLC post-column assays are developed and optimised. Besides, the scientific research on optimisation of equipment complementation and system constitution for the screening of various antioxidants of plant origin, for the evaluation of their distribution in different plant organs, and for quality control by antioxidant activity is performed. DPPH and ABTS post-column assays are optimised for the rapid identification and activity determination of antioxidants in complex mixtures after the chromatographical separation of analytes. The reseach evaluating antioxidant activity of phenolic compounds in the extracts of herbal raw materials is conducted as well.

Selected Publications:

  1. Uminska, K., Gudžinskas, Z., Ivanauskas, L., Georgiyants, V., Kozurak, A., Skibytska, M., Mykhailenko, O. (2023). Amino acid profiling in wild Chamaenerion angustifolium populations applying chemometric analysis. Journal of Applied Pharmaceutical Science, 13 (5), 171–180. doi: https://doi.org/10.7324/japs.2023.108931

  2. Stabrauskiene, J., Marksa, M., Ivanauskas, L., Viskelis, P., Viskelis, J., Bernatoniene, J. (2023). Citrus × paradisi L. Fruit Waste: The Impact of Eco-Friendly Extraction Techniques on the Phytochemical and Antioxidant Potential. Nutrients, 15 (5), 1276. doi: https://doi.org/10.3390/nu15051276

  3. Vilkickyte, G., Petrikaite, V., Marksa, M., Ivanauskas, L., Jakstas, V., Raudone, L. (2023). Fractionation and Characterization of Triterpenoids from Vaccinium vitis-idaea L. Cuticular Waxes and Their Potential as Anticancer Agents. Antioxidants, 12 (2), 465. doi: https://doi.org/10.3390/antiox12020465

  4. Radušienė, J., Karpavičienė, B., Raudone, L., Vilkickyte, G., Çırak, C., Seyis, F., Yayla, F., Marksa, M., Rimkienė, L., Ivanauskas, L. (2023). Trends in Phenolic Profiles of Achillea millefolium from Different Geographical Gradients. Plants, 12 (4), 746. doi: https://doi.org/10.3390/plants12040746

  5. Saunoriūtė, S., Ragažinskienė, O., Raudonė, L., Ivanauskas, L., Marksa, M. (2023). Phenolic content and antioxidant activity in medicinal raw material of introduced Artemisia L. species in Lithuania. Chemija, 34 (1). doi: https://doi.org/10.6001/chemija.2023.34.1.6

  6. Jarukas, L., Vitkevicius, K., Mykhailenko, O., Bezruk, I., Georgiyants, V., Ivanauskas, L. (2022). Effective Isolation of Picrocrocin and Crocins from Saffron: From HPTLC to Working Standard Obtaining. Molecules, 2022, 27(13), 4286. doi: https://doi.org/10.3390/molecules27134286 

  7. Мykhailenko, O., Chetvernya, S., Bezruk, I., Buydin, Y., Dhurenko, N., Рalamarchuk, O., Ivanauskas, L., Georgiyants, V. (2022). Bioactive constituents of Iris hybrida (Iridaceae): Processing effect. Biomedical Chromatography, 36 (7), e5369. doi: https://doi.org/10.1002/bmc.5369