David Vetchy

Veterinary and Pharmaceutical University, Czech Republic
Proffesor
Faculty of Pharmacy

Scopus Profile: link
Web of Science profile: link



Professional (scientific) interests:
preparation and evaluation of medical forms with poorly soluble and hardly absorbable APIs; and formulation and evaluation of medical forms with controlled drug release (especially pellets and mucoadhesive films)

Selected Publications:

  1. Brus, J., Urbanova, M., Czernek, J., Pavelkova, M., Kubova, K., Vyslouzil, J. et. al. (2017). Structure and Dynamics of Alginate Gels Cross-Linked by Polyvalent Ions Probed via Solid State NMR Spectroscopy. Biomacromolecules, 18 (8), 2478–2488. doi: http://doi.org/10.1021/acs.biomac.7b00627 
  1. Kubova, K., Peček, D., Hasserová, K., Doležel, P., Pavelková, M., Vyslouzil, J. et. al. (2017). The influence of thermal treatment and type of insoluble poly(meth)acrylates on dissolution behavior of very soluble drug from hypromellose matrix tablets evaluated by multivariate data analysis. Pharmaceutical Development and Technology, 22 (2), 206–217. doi: http://doi.org/10.1080/10837450.2016.1193191 
  1. Jekl, V., Hauptman, K., Minarikova, A., Kohutova, S., Knotek, Z., Gajdziok, J. et. al. (2016). Pharmacokinetic study of benzylpenicillin potassium after intramuscular administration in rabbits. Veterinary Record, 179 (1), 18.1–18. doi: http://doi.org/10.1136/vr.103531 
  1. Urbanova, M., Gajdosova, M., Steinhart, M., Vetchy, D., Brus, J. (2016). Molecular-Level Control of Ciclopirox Olamine Release from Poly(ethylene oxide)-Based Mucoadhesive Buccal Films: Exploration of Structure–Property Relationships with Solid-State NMR. Molecular Pharmaceutics, 13 (5), 1551–1563. doi: http://doi.org/10.1021/acs.molpharmaceut.6b00035 
  1. Franc, A., Muselłk, J., Goněc, R., Vetchý, D. (2016). Biphasic dissolution method for quality control and assurance of drugs containing active substances in the form of weak acid salts. Acta Pharmaceutica, 66 (1), 139–145. doi: http://doi.org/10.1515/acph-2016-0010 
  1. Vetchý, D., Landová, H., Gajdziok, J., Doležel, P., Daněk, Z., Štembírek, J. (2014). Determination of dependencies among in vitro and in vivo properties of prepared mucoadhesive buccal films using multivariate data analysis. European Journal of Pharmaceutics and Biopharmaceutics, 86 (3), 498–506. doi: http://doi.org/10.1016/j.ejpb.2013.12.002 
  1. Pitschmann, V., Kobliha, Z., Tusarová, I., Bártová, L., Vetchý, D., Bobál, P. (2014). A new detection tube to detect hydrogen cyanide in the air. Chemical Industry and Chemical Engineering Quarterly, 20 (2), 155–161. doi: http://doi.org/10.2298/ciceq120504118p