Lucjusz Zaprutko

Poznan University of Medical Sciences, Poland
Professor, Pharmaceutical Faculty

Scopus profile: link
Researcher ID: DZI-4330-2022
ID ORCID: http://orcid.org/0000-0003-1121-6272

Professional (scientific) interests: Medicinal chemistry, Organic chemistry, Natural compounds, Triterpenes, Isoprenoids, Heterocyclic compounds, Azoles, Cosmetics, Fragrances

Selected Publications:

  1. Bednarczyk-Cwynar, B., Leśków, A., Szczuka, I., Zaprutko, L., Diakowska, D. (2023). The Effect of Oleanolic Acid and Its Four New Semisynthetic Derivatives on Human MeWo and A375 Melanoma Cell Lines. Pharmaceuticals, 16 (5), 746. doi: https://doi.org/10.3390/ph16050746

  2. Sowa-Kasprzak, K., Totoń, E., Kujawski, J., Olender, D., Lisiak, N., Zaprutko, L., Rubiś, B., Kaczmarek, M., Pawełczyk, A. (2023). Synthesis, Cytotoxicity and Molecular Docking of New Hybrid Compounds by Combination of Curcumin with Oleanolic Acid. Biomedicines, 11 (6), 1506. doi: https://doi.org/10.3390/biomedicines11061506

  3. Pawełczyk, A., Nowak, R., Gazecka, M., Jelińska, A., Zaprutko, L., Zmora, P. (2023). Novel Molecular Consortia of Cannabidiol with Nonsteroidal Anti-Inflammatory Drugs Inhibit Emerging Coronaviruses’ Entry. Pathogens, 12 (7), 951. doi: https://doi.org/10.3390/pathogens12070951

  4. Sowa-Kasprzak, K., Józkowiak, M., Olender, D., Pawełczyk, A., Piotrowska-Kempisty, H., Zaprutko, L. (2023). Curcumin–Triterpene Type Hybrid as Effective Sonosensitizers for Sonodynamic Therapy in Oral Squamous Cell Carcinoma. Pharmaceutics, 15 (7), 2008. doi: https://doi.org/10.3390/pharmaceutics15072008

  5. Olender, D., Józkowiak, M., Piotrowska-Kempisty, H., Sowa-Kasprzak, K., Zaprutko, L., Muszalska-Kolos, I., Baranowska-Wójcik, E., Szwajgier, D. (2023). Curcuminoid Chalcones: Synthesis, Stability, and New Neuroprotective and Sonosensitising Activities. Pharmaceuticals, 16 (9), 1331. doi: https://doi.org/10.3390/ph16091331

  6. Lisiak, N., Dzikowska, P., Wisniewska, U., Kaczmarek, M., Bednarczyk-Cwynar, B., Zaprutko, L., Rubis, B. (2023). Biological Activity of Oleanolic Acid Derivatives HIMOXOL and Br-HIMOLID in Breast Cancer Cells Is Mediated by ER and EGFR. International Journal of Molecular Sciences, 24 (6), 5099. doi: https://doi.org/10.3390/ijms24065099

  7. Pawełczyk, A., Żwawiak, J., Zaprutko, L. (2023). Kumquat Fruits as an Important Source of Food Ingredients and Utility Compounds. Food Reviews International, 39 (2), 875–895. doi: https://doi.org/10.1080/87559129.2021.1928179