Nomograms of vascularization indices of uterine health women, studyed with the use of three-dimensional energy dopplerography

Authors

DOI:

https://doi.org/10.15587/2519-4798.2018.148475

Keywords:

three-dimensional echography, VOCAL option, nomograms, hemodynamics of the uterus body and cervix

Abstract

Differential diagnosis of benign and malignant tumors using the Doppler method is based on the fact that the blood supply of these tumors has its own peculiarities.

The aim of the research is to study the nomograms of volumetric blood flow rates of the body and cervix of healthy women of different ages by means of three - dimensional angioplasty in search of differential diagnostic criteria for simple, proliferating leiomyoma and sarcoma of the uterus in the long term.

Materials and methods. 157 practically healthy women were examined. The patients were divided into women of reproductive age, women in perimenopausal women and climacteric women. With the help of 3D uterine reconstruction using the energy mapping function and VOCAL (Virtual Organ Computer Aided Analysis), an objective assessment of the hemodynamics of the body and the cervix was performed by calculating the vascularization index (VI), which characterizes the percentage ratio of blood vessels to a certain extent tissues, blood flow index (FI), which characterizes the intensity of blood flow, which shows the volume of blood cells that move in the vessels at the time of the study and vascularization – flow index (VFI), which is an indicator of perfusion of the organ.

Results. As a result, the nomograms of the volumetric blood flow (VI, FI, VFI) parameters of the uterus body were improved, and the nomograms of the volumetric blood flow (VI, FI, VFI) parameters of the cervix of healthy women were designed and the patterns of their changes depending on age were determined.

The authors have established that the technique of three-dimensional echography-3D - reconstruction of the uterus in angiography with the use of the VOCAL option with the determination of volumetric blood flow parameters allows to objectively evaluate the degree of vascularization of the body and cervix of healthy women of all ages, preventing a subjective approach to assessing hemodynamics, which is present in the two-dimensional energy Doppler mapping mode.

Conclusions. Based on the obtained results, the development of differential diagnostic criteria for benign, borderline and malignant tumors of myometrium with the determination of quantitative parameters of 3D – energy dopplerography will be based on the prospect, which will significantly increase the level of ultrasound diagnostics in gynecologic oncology and will allow to develop a rational tactic for treating patients

Author Biographies

Kirill Yakovenko, State Institution «Grigoriev Institute for Medical Radiology of National Academy of Medical Sciences of Ukraine» Pushkinska str., 82, Kharkiv, Ukraine, 61024

Postgraduate student

Tamara Tamm, Kharkiv Medical Academy of Postgraduate Education Amosova str., 58, Kharkiv, Ukraine, 61176

MD, Professor, Head of Department

Department of Surgery and Proctology

Elena Yakovenko, Kharkiv Medical Academy of Postgraduate Education Amosova str., 58, Kharkiv, Ukraine, 61176

PhD, Associate Professor

Department of Genetics, Obstetrics, Gynecology and Fetal Medicine

References

  1. Bulanov, M. N. (2012). Ul'trazvukovaya ginekologiya: kurs lektsiy [Ultrasonic gynecology: a course of lectures: in two parts]. Ch. II: Gl. 14–24. Moscow: Publishing House Vidar, 456.
  2. Zaporozhchenko, M. B. (2015). Sostoyaniye regional'noy gemodinamiki v sosudakh matki u zhenshchin reproduktivnogo vozrasta s leyomiomoy matki [The state of regional hemodynamics in uterine vessels in women of reproductive age with uterine leiomyoma]. Arta Medica, 1 (54), 41–44.
  3. Adamyan, L. V. (Ed.) (2015). Mioma matki: diagnostika, lecheniye, reabilitatsiya. Klinicheskiye rekomendatsii po vedeniyu bol'nykh [Uterine fibroids: diagnosis, treatment, rehabilitation. Clinical recommendations for managing patients]. Moscow: GBOU VPO «The First Moscow State Medical University», 101.
  4. Bulun, S. E. (2013). Uterine Fibroids. New England Journal of Medicine, 369 (14), 1344–1355. doi: http://doi.org/10.1056/nejmra1209993
  5. Rauh-Hain, J. A., del Carmen, M. G. (2013). Endometrial Stromal Sarcoma. Obstetrics & Gynecology, 122 (3), 676–683. doi: http://doi.org/10.1097/aog.0b013e3182a189ac
  6. Reed, N. (2012). The management of uterine sarcomas. Gunes publish, 399–404.
  7. Ozerskaya, I. A.; Rodionova, L. S. (Ed.) (2013). Ekhografiya v ginekologii [Echography in gynecology]. Moscow: Publishing House Vidar, 564.
  8. Ozerskaya, I. A., Devitskiy, A. A. (2014). Ul'trazvukovaya differentsial'naya diagnostika uzlov miometriya v zavisimosti ot gistologicheskogo stroyeniya opukholi [Ultrasound differential diagnosis of myometrium nodes depending on the histological structure of the tumor]. Medical imaging, 2, 110–121.
  9. Anisimov, A. V. (2010). VOCAL – kolichestvennyy analiz v trekhmernoy ekhografii [VOCAL – quantitative analysis in three-dimensional echography]. SonoAce Ultrasound, 21, 89–95.
  10. Ozerskaya, I. A., Shcheglova, Ye. A., Sirotinkina, Ye. V., Dolgova, Ye. P., Shul'gina, S. V. (2010). Fiziologicheskiye izmeneniya gemodinamiki matki u zhenshchin reproduktivnogo, peri- i postmenopauzal'nogo periodov [Physiological changes in the hemodynamics of the uterus in women of reproductive, peri- and postmenopausal periods]. SonoAce Ultrasound, 21, 40–56.
  11. Lysenko, O. V. (2013). Primeneniye trekhmernoy ekhografii s optsiyey energeticheskogo dopplera v diagnostike giperplasticheskikh protsessov v endometrii [Application of three-dimensional echography with the option of an energy Doppler in the diagnosis of hyperplastic processes in the endometrium]. The Russian Bulletin of the Obstetrician-Gynecologist, 5, 70–74.
  12. Kim, A., Lee, J. Y., Chun, S., Kim, H. Y. (2015). Diagnostic utility of three-dimensional power Doppler ultrasound for postmenopausal bleeding. Taiwanese Journal of Obstetrics and Gynecology, 54 (3), 221–226. doi: http://doi.org/10.1016/j.tjog.2013.10.043
  13. Ozerskaya, I. A. Devitskiy, A. A. (2014). Izmeneniye gemodinamiki matki, porazhennoy miomoy u zhenshchin reproduktivnogo i premenopauzal'nogo vozrasta [Change in hemodynamics of the uterus affected by myoma in women of reproductive and premenopausal age]. Medical visualization, 1, 70–80.
  14. El-Mazny, A., Abou-Salem, N., ElShenoufy, H. (2013). Three-dimensional power Doppler study of endometrial and subendometrial microvascularization in women with intrauterine device–induced menorrhagia. Fertility and Sterility, 99 (7), 1912–1915. doi: http://doi.org/10.1016/j.fertnstert.2013.01.151
  15. Lysenko, O. V. (2013). Ispol'zovaniye trekhmernoy ekhografii s optsiyey energeticheskopgo dopplera pri podozrenii na giperplaziyu endometriya u zhenshchin pozdnego reproduktivnogo vozrasta [Use of three-dimensional echography with the option of energy Doppler with suspicion of endometrial hyperplasia in women of late reproductive age]. Journal of Obstetrics and Women's Diseases: Proceedings of the II National Congress "Discussion Issues of Modern Obstetrics" and the Pre-Congress Training Course of the XI World Congress on Perinatal Medicine, LX II (2), 126–132.

Published

2018-11-27

How to Cite

Yakovenko, K., Tamm, T., & Yakovenko, E. (2018). Nomograms of vascularization indices of uterine health women, studyed with the use of three-dimensional energy dopplerography. ScienceRise: Medical Science, (7 (27), 46–54. https://doi.org/10.15587/2519-4798.2018.148475

Issue

Section

Medical Science