The relation of atherosclerotic lesions of BCA against the background of COPD in patients aged 40-60 years. Review of the literature and retrospective analysis

Authors

DOI:

https://doi.org/10.15587/2519-4798.2021.246598

Keywords:

atherosclerosis, chronic obstructive pulmonary disease, chronic inflammation, matrix metalloproteinases, lipid profile, duplex scanning, sirutins

Abstract

The aim: to determine the possible relationship between chronic obstructive pulmonary disease and the presence of atherosclerosis of the brachiocephalic vessels in persons aged 40–60 years for the possibility of early prevention of cardiovascular events.

Materials and methods: to do this, we reviewed articles using open sources such as PubMED, Medscape and Cochrane library, highlighting the relationship between the development of atherosclerosis and the presence and severity of COPD. Also, based on the University Clinic of ONMedU and Military Clinical Center of the Southern Region, a retrospective analysis of patients with an inconclusively confirmed diagnosis of COPD and conducted biochemical blood tests was carried out in order to study changes in the lipid profile and the presence of BCS in these patients.

Result: In the course of a retrospective analysis of patients, a relationship was found between the presence of BCA atherosclerosis and the presence of COPD, and based on the literature data, a parallel was drawn between changes in the lipid profile in patients with COPD. But, in view of the insufficient number of patients, this topic requires additional research.

Conclusions: thus, based on the obtained data, it can be concluded that there is a connection between the presence of COPD, changes in the lipid profile, and the presence of BCА atherosclerosis. This connection can become one of the key mechanisms of early diagnosis of BCА atherosclerosis

Author Biographies

Iryna Andrusyshyna , Odessa National Medical University

Assistant

Department of Internal Medicine No. 2

Viktoria Batashova-Galinska, Odessa National Medical University

PhD, Associate Professor

Department of Internal Medicine No. 2

Tetiana Horbenko, Military Medical Clinical Center of Southern Region

PhD, Head of the Department

Department of Pulmonology

Leonid Kholopov, Odessa National Medical University

Philosophy Doctor, Associate Professor

Department of Internal Medicine No. 2

References

  1. MeSH. Сochrane library. Available at https://www.cochranelibrary.com/advanced-search/mesh
  2. Kovalenko, V. M., Kornatskyi, V. M. (Eds.) (2021). Medyko-sotsialni problemy zdorovia v umovakh pandemii COVID-19. Cherkasy: Tretiakov O.M., 240.
  3. osnovnykh prichin smerti. Vsemirnaya organizatsiya zdravookhraneniya (2018). WHO. Available at: https://www.who.int/ru/news-room/fact-sheets/detail/the-top-10-causes-of-death
  4. Man, S. F., Connett, J. E, Anthonisen, N. R., Wise, R. A., Tashkin, D. P., Sin, D. D. (2006). C-reactive protein and mortality in mild to moderate chronic obstructive pulmonary disease. Thorax, 61 (10), 849–853. doi: http://doi.org/10.1136/thx.2006.059808
  5. Anthonisen, N. R., Connett, J. E., Enright, P. L., Manfreda, J. (2002). Hospitalizations and Mortality in the Lung Health Study. American Journal of Respiratory and Critical Care Medicine, 166 (3), 333–339. doi: http://doi.org/10.1164/rccm.2110093
  6. Sin, D. D., Anthonisen, N. R., Soriano, J. B., Agusti, A. G. (2006). Mortality in COPD: role of comorbidities. European Respiratory Journal, 28 (6), 1245–1257. doi: http://doi.org/10.1183/09031936.00133805
  7. Calverley, P. M. A., Anderson, J. A., Celli, B., Ferguson, G. T., Jenkins, C., Jones, P. W. et. al. (2007). Salmeterol and Fluticasone Propionate and Survival in Chronic Obstructive Pulmonary Disease. New England Journal of Medicine, 356(8), 775–789. doi: http://doi.org/10.1056/nejmoa063070
  8. Corbi, G., Bianco, A., Turchiarelli, V., Cellurale, M., Fatica, F., Daniele, A. et. al. (2013). Potential Mechanisms Linking Atherosclerosis and Increased Cardiovascular Risk in COPD: Focus On Sirtuins. International Journal of Molecular Sciences, 14 (6), 12696–12713. doi: http://doi.org/10.3390/ijms140612696
  9. Gunay, S., Sariaydin, M., Acay, A. (2016). New Predictor of Atherosclerosis in Subjects With COPD: Atherogenic Indices. Respiratory Care, 61 (11), 1481–1487. doi: http://doi.org/10.4187/respcare.04796
  10. Kraen, M., Frantz, S., Nihlén, U., Engström, G., Löfdahl, C. G., Wollmer, P., Dencker, M. (2019). Matrix Metalloproteinases in COPD and atherosclerosis with emphasis on the effects of smoking. PLOS ONE, 14 (2), e0211987. doi: http://doi.org/10.1371/journal.pone.0211987
  11. Pecci, R., De La Fuente Aguado, J., Sanjurjo Rivo, A. B. et. al. (2012). Peripheral arterial disease in patients with chronic obstructive pulmonary disease. International Angiology, 31 (5), 444–453. Available at: https://www.minervamedica.it/en/journals/international-angiology/article.php?cod=R34Y2012N05A0444
  12. Golpe, R., Mateos-Colino, A., González-Juanatey, C., Testa-Fernández, A., Domínguez-Pin, N., Martín-Vázquez, F. J. (2017). Subclinical Carotid Atherosclerosis in COPD Cases and Control Smokers: Analysis in Relation with COPD Exacerbations and Exacerbation-like Episodes. Lung, 195 (2), 185–191. doi: http://doi.org/10.1007/s00408-017-9986-4
  13. Tuleta, I., Farrag, T., Busse, L., Pizarro, C., Schaefer, C., Pingel, S. et. al. (2017). High prevalence of COPD in atherosclerosis patients. International Journal of Chronic Obstructive Pulmonary Disease, 12, 3047–3053. doi: http://doi.org/10.2147/copd.s141988
  14. Agusti, A., Calverley, P. M., Celli, B., Coxson, H. O., Edwards, L. D. et. al. (2010). Characterisation of COPD heterogeneity in the ECLIPSE cohort. Respiratory Research, 11 (1). doi: http://doi.org/10.1186/1465-9921-11-122
  15. Suissa, S., Dell’Aniello, S., Ernst, P. (2012). Long-term natural history of chronic obstructive pulmonary disease: severe exacerbations and mortality. Thorax, 67 (11), 957–963. doi: http://doi.org/10.1136/thoraxjnl-2011-201518
  16. Wilson, P. W. F., D’Agostino, R. B., Levy, D., Belanger, A. M., Silbershatz, H., Kannel, W. B. (1998). Prediction of Coronary Heart Disease Using Risk Factor Categories. Circulation, 97 (18), 1837–1847. doi: http://doi.org/10.1161/01.cir.97.18.1837
  17. Lee, H. M., Lee, J., Lee, K., Luo, Y., Sin, D. D., Wong, N. D. (2012). Relation Between COPD Severity and Global Cardiovascular Risk in US Adults. Chest, 142 (5), 1118–1125. doi: http://doi.org/10.1378/chest.11-2421
  18. Mosenifar, Z., Harrington, A., Nikhanj, N. S., Kamangar, N. (2020). What is the BODE index, and how is used to estimate the prognosis of chronic obstructive pulmonary disease (COPD)? MedScape. Available at: https://www.medscape.com/answers/297664-7357/what-is-the-bode-index-and-how-is-used-to-estimate-the-prognosis-of-chronic-obstructive-pulmonary- disease-copd
  19. Cazzola, M., Calzetta, L., Matera, M. G., Muscoli, S., Rogliani, P., Romeo, F. (2015). Chronic obstructive pulmonary disease and coronary disease: COPDCoRi, a simple and effective algorithm for predicting the risk of coronary artery disease in COPD patients. Respiratory Medicine, 109 (8), 1019–1025. doi: http://doi.org/10.1016/j.rmed.2015.05.021
  20. Domenech, A., Muñoz-Montiel, A., García-Casares, N., Rioja, J., Ruiz-Esteban, P., Gutierrez- Castaño, P. et. al. (2018). High risk of subclinical atherosclerosis in COPD exacerbator phenotype. Respiratory Medicine, 141, 165–171. doi: http://doi.org/10.1016/j.rmed.2018.07.004
  21. Sharma, H., Kapur, P., Jalali, R. K., Dubey, K. (2019). Atherosclerosis risk assessment in patients with chronic obstructive pulmonary disease: a case-control study. Therapeutics and Clinical Risk Management, 15, 1061–1071. doi: http://doi.org/10.2147/tcrm.s216180
  22. Sugiura, T., Dohi, Y., Takagi, Y., Yokochi, T., Yoshikane, N., Suzuki, K. et. al. (2020). Close Association between Subclinical Atherosclerosis and Pulmonary Function in Middle-Aged Male Smokers. Journal of Atherosclerosis and Thrombosis, 27 (11), 1230–1242. doi: http://doi.org/10.5551/jat.55996

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Published

2021-11-30

How to Cite

Andrusyshyna , I., Batashova-Galinska, V., Horbenko, T., & Kholopov, L. (2021). The relation of atherosclerotic lesions of BCA against the background of COPD in patients aged 40-60 years. Review of the literature and retrospective analysis. ScienceRise: Medical Science, (6(45), 10–14. https://doi.org/10.15587/2519-4798.2021.246598

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Medical Science