Model of spatial structure of human AIMP1/р43 protein

Authors

  • Дмитро Миколайович Ложко Institute of Molecular Biology and Genetics of NASU Zabolotnogo str., 150, Kyiv, Ukraine, 03680, Ukraine
  • Олександр Іванович Корнелюк Institute of Molecular Biology and Genetics of NASU Zabolotnogo str., 150, Kyiv, Ukraine, 03680, Ukraine

DOI:

https://doi.org/10.15587/2519-8025.2016.81822

Keywords:

AIMP1/р43, cytokines, circular dichroism (CD), computer modeling

Abstract

Computer modeling of 3D structure of full-length AIMP1/р43 - component of aminoacyl tRNA synthetase complex in higher eukaryotes, was performed. The model of the spatial structure of the dimer AIMP1/р43 was obtained. Experimental data on the content of the secondary structure of AIMP1/р43 was determined by circular dichroism method. The spatial structure of AIMP1/р43 allows to carry out structural and functional analysis of the interaction with other biologically important molecules

Author Biographies

Дмитро Миколайович Ложко, Institute of Molecular Biology and Genetics of NASU Zabolotnogo str., 150, Kyiv, Ukraine, 03680

Research assistant

Олександр Іванович Корнелюк, Institute of Molecular Biology and Genetics of NASU Zabolotnogo str., 150, Kyiv, Ukraine, 03680

Corresponding Member of NASU, Doctor of Biological Science, professor

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Published

2016-11-03

How to Cite

Ложко, Д. М., & Корнелюк, О. І. (2016). Model of spatial structure of human AIMP1/р43 protein. ScienceRise: Biological Science, (2 (2), 41–46. https://doi.org/10.15587/2519-8025.2016.81822

Issue

No. 2 (2) (2016)

Section

Biological Sciences

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Copyright (c) 2016 Дмитро Миколайович Ложко, Іванович Корнелюк Олександр

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