Research of influence of Trigonella foenum graecum L. on antioxidant enzymes activity in high calorie diet-induced obese rats

Authors

DOI:

https://doi.org/10.15587/2519-8025.2017.95343

Keywords:

fenugreek, obesity, high calorie diet, rats, adipose tissue, superoxide dismutase, catalase, glutathione peroxidase

Abstract

Aim The present study was undertaken with an objective to examine the effects of powder seeds Trigonella foenum graecum L on adipose tissue weight gain and disfunction antioxidant enzymes induced by high calorie diet and its reduction by adding 2% of fenugreek seed

Methods The activity of superoxide dismutase and catalase were determined according to Sirota and Korolyuk methods. The activities of glutathione peroxidase was estimated according to methods described by Razygraev.

Result It was shown increase fat mass and dysfunction of antioxidant system in animals with obese. Addition to HCD 2 % fine powder seeds fenugreek led to normalization of the studied parameters.

Conclusions As in the present study beneficial decrease in adipose tissue weight is seen, fenugreek can be accepted as one of the herbal preparation for treating obesity. Further study is needed for exploring the other mechanism of anti-obesity by fenugreek.

 

Author Biography

Victoria Konopelniuk, Taras Shevchenko Kyiv National University Volodymyrska str., 64/13, Kyiv, Ukraine, 01601

PhD, Senior researcher

SRL "Physico-Chemical Biology", department of Experimental Biology, ESC "Institute of Biology and Medicine"

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Published

2017-04-26

How to Cite

Konopelniuk, V. (2017). Research of influence of Trigonella foenum graecum L. on antioxidant enzymes activity in high calorie diet-induced obese rats. ScienceRise: Biological Science, (2 (5), 18–24. https://doi.org/10.15587/2519-8025.2017.95343

Issue

No. 2 (5) (2017)

Section

Biological Sciences

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Copyright (c) 2017 Victoria Konopelniuk

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