Rare occupational infection: two cases of paravaccinia – viral disease of milkers at Bukovyna

Authors

  • Andrii Sokol Higher state educational establishment “Bukovinian State Medical University” Teatralna sq., 2, Chernivtsi, Ukraine, 58002, Ukraine https://orcid.org/0000-0002-1320-1122
  • Yurii Randiuk Higher State Educational Institution of Ukraine " Bukovinian State Medical University " Teatralna sq., 2, Chernivtsi, Ukraine, 58002, Ukraine https://orcid.org/0000-0003-2154-8115
  • Aniuta Sydorchuk Higher State Educational Institution of Ukraine " Bukovinian State Medical University " Teatralna sq., 2, Chernivtsi, Ukraine, 58002, Ukraine https://orcid.org/0000-0002-1959-6612
  • Nonna Bohachyk Higher State Educational Institution of Ukraine " Bukovinian State Medical University " Teatralna sq., 2, Chernivtsi, Ukraine, 58002, Ukraine https://orcid.org/0000-0002-8915-7244
  • Yadviha Venhlovs’ka Higher State Educational Institution of Ukraine " Bukovinian State Medical University " Teatralna sq., 2, Chernivtsi, Ukraine, 58002, Ukraine https://orcid.org/0000-0002-7263-8703
  • Natalya Kaspruk State Institution “Regional medical union Ministry of Internal affairs of Ukraine at Chernivtsi region” Heroiv Maidanu str., 228, Chernivtsi, Ukraine, 58013, Ukraine
  • Volodymyr Tymoschuk Municipal Medical Institution «City clinics No. 2» Lesi Ukrainky str., 11, Chernivtsi, Ukraine, 58002, Ukraine
  • Orysia Oliynuk Municipal medical institution «City clinics No. 5» Stetsenka str., 5, Chernivtsi, Ukraine, 58022, Ukraine

DOI:

https://doi.org/10.15587/2519-4798.2018.132591

Keywords:

occupational infectious disease, parapoxviruses, paravaccinia, milker’s nodules, zoonoses, rare infections

Abstract

The article presents two clinical cases of rare zoogenous professional viral infectious disease caused by DNA-containing parapoxvirus, which is transmitted directly during contact, most often in the milking of cows, which also caused the disease to be called "milker’s nodules", but the risk of infection is also subject to butchers, farmers and agro-tourists.

The clinical course of two cases of paravaccinia is described in detail, the virus infection begins 5-15 days after inoculation in the form of a violet erythematous rounded node with a clear compression in the center and surrounding its erythematous ring.

The need for a clear elucidation of the epidanamnesis, which may facilitate differentiation with the Rhizenbach erysipeloid, skin neoplasms, contagious mollusks and anthrax carbuncle, is emphasized.

According to modern literature, in farms, the appearance of nodules may occur in people with impaired immunity, which also has an increased risk of serious complications. The nodules independently dissolve in persons without weakened immunity and heal without the formation of a scar. There is evidence that a para-vaccine virus can become a source of antigen for the development of multiform erythema.

Analyzing the data of professional foreign and domestic articles, paravaccinia is a self-limiting viral infection, the prevention of which is reduced to compliance with sanitary and hygiene rules for milking cows, animal care, the use of antiseptics in veterinary and farm.

Scientific interest in the study of the state of the immune system is susceptible to the virus, especially the clinical course of the comorbid immunodeficiency pathology of various genesis, since the question remains unclear.

The unique structure and replication process of parapoxviruses is being intensively investigated, and these data may open up promising therapeutic options for treating cancer.

General practitioners-family medicine and practitioners of other specialties-infectious disease specialists, dermatologists, oncologists and surgeons should remember the features of this infection, since the high probability of misidentification for persons who had not previously met her could lead to unwanted use of too intense methods of treatment

Author Biographies

Andrii Sokol, Higher state educational establishment “Bukovinian State Medical University” Teatralna sq., 2, Chernivtsi, Ukraine, 58002

PhD, Professor

Department of Internal Medicine and Infectious Diseases

Yurii Randiuk, Higher State Educational Institution of Ukraine " Bukovinian State Medical University " Teatralna sq., 2, Chernivtsi, Ukraine, 58002

PhD, Associate Professor

Department of Internal Medicine and Infectious Diseases

Aniuta Sydorchuk, Higher State Educational Institution of Ukraine " Bukovinian State Medical University " Teatralna sq., 2, Chernivtsi, Ukraine, 58002

PhD, Associate Professor

Department of Internal Medicine and Infectious Diseases

Nonna Bohachyk, Higher State Educational Institution of Ukraine " Bukovinian State Medical University " Teatralna sq., 2, Chernivtsi, Ukraine, 58002

PhD, Assistant

Department of Internal Medicine and Infectious Diseases

Yadviha Venhlovs’ka, Higher State Educational Institution of Ukraine " Bukovinian State Medical University " Teatralna sq., 2, Chernivtsi, Ukraine, 58002

PhD, Assistant

Department of Internal Medicine and Infectious Diseases

Natalya Kaspruk, State Institution “Regional medical union Ministry of Internal affairs of Ukraine at Chernivtsi region” Heroiv Maidanu str., 228, Chernivtsi, Ukraine, 58013

Head of Department

Volodymyr Tymoschuk, Municipal Medical Institution «City clinics No. 2» Lesi Ukrainky str., 11, Chernivtsi, Ukraine, 58002

Head of Department

Neurological Department

Orysia Oliynuk, Municipal medical institution «City clinics No. 5» Stetsenka str., 5, Chernivtsi, Ukraine, 58022

Doctor

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Published

2018-05-31

How to Cite

Sokol, A., Randiuk, Y., Sydorchuk, A., Bohachyk, N., Venhlovs’ka, Y., Kaspruk, N., Tymoschuk, V., & Oliynuk, O. (2018). Rare occupational infection: two cases of paravaccinia – viral disease of milkers at Bukovyna. ScienceRise: Medical Science, (4 (24), 48–51. https://doi.org/10.15587/2519-4798.2018.132591

Issue

Section

Medical Science