Organ-saving and reconstructive plastic surgery of breast cancer

Authors

  • Tamara Tamm Kharkiv Medical Academy of Postgraduate Education Amosova str., 58, Kharkiv, Ukraine, 61176, Ukraine
  • Yuri Vinnуk Kharkiv Medical Academy of Postgraduate Education Amosova str., 58, Kharkiv, Ukraine, 61176, Ukraine
  • Volodimir Starikov Kharkiv National Medical University Nauky ave., 4, Kharkiv, Ukraine, 61022, Ukraine
  • Oleksandra Prokopyuk Kharkiv Medical Academy of Postgraduate Education Amosova str., 58, Kharkiv, Ukraine, 61176, Ukraine https://orcid.org/0000-0001-5560-8935
  • Grіgory Oleynik Kharkiv Medical Academy of Postgraduate Education Amosova str., 58, Kharkiv, Ukraine, 61176, Ukraine https://orcid.org/0000-0002-7445-553X
  • Vadym Vlasenko Molecule Medical Center Hoholia str., 7, Kharkiv, Ukraine, 61057, Ukraine https://orcid.org/0000-0002-8215-1958

DOI:

https://doi.org/10.15587/2519-4798.2020.209149

Keywords:

breast cancer, surgical treatment, organ-saving operations, breast reconstruction, quality of life

Abstract

Surgical treatment of breast cancer is an integral part of complex treatment. In recent years, the goal of treatment is not only to ensure long-term relapse-free and metastatic survival, but also a proper quality of life, which requires new approaches to surgery.

The aim of the literature review was to analyze current trends in the development of methods of surgical treatment of the breast cancer and ways to improve immediate and late results.

The results of the analysis and discussion. Until recently, radical mastectomy was performed to treat breast cancer, which causes long-term lymphovenous complications and significantly impairs the quality of life of patients. In recent decades, there has been a development of breast cancer surgery in the direction of the introduction of organ-saving and reconstructive plastic surgery with the improvement of technology for their implementation. There is no generally accepted concept of the optimal method of surgical treatment, both in terms of the volume of the operation and the choice of the method of reconstruction.

Conclusions. The problem of choosing the optimal method of surgical treatment of breast cancer, which should provide oncological radicalism and at the same time a good cosmetic result remains unresolved and requires further research

Author Biographies

Tamara Tamm, Kharkiv Medical Academy of Postgraduate Education Amosova str., 58, Kharkiv, Ukraine, 61176

MD, Professor

Department of Surgery and Proctology

Yuri Vinnуk, Kharkiv Medical Academy of Postgraduate Education Amosova str., 58, Kharkiv, Ukraine, 61176

MD, Professor, Head of Departmen

Department of Oncology Surgery, Radiation Therepy, Palliative Care

Volodimir Starikov, Kharkiv National Medical University Nauky ave., 4, Kharkiv, Ukraine, 61022

MD, Professor

Department of Oncology

Oleksandra Prokopyuk, Kharkiv Medical Academy of Postgraduate Education Amosova str., 58, Kharkiv, Ukraine, 61176

PhD, Associate Professor

Department of Obstetrics, Gynecology and Oncology

Grіgory Oleynik, Kharkiv Medical Academy of Postgraduate Education Amosova str., 58, Kharkiv, Ukraine, 61176

MD, Professor

Department of Combustiology, Reconstructive and Plastic Surgery

Vadym Vlasenko, Molecule Medical Center Hoholia str., 7, Kharkiv, Ukraine, 61057

PhD

References

  1. Global, regional, and national life expectancy, all-cause mortality, and cause-specific mortality for 249 causes of death, 1980–2015: a systematic analysis for the Global Burden of Disease Study 2015 (2016). Lancet, 388, 1459–1544. Available at: http://www.thelancet.com/pdfs/journals/lancet/PIIS0140-6736(16)31012-1.pdf
  2. Ghoncheh, M., Pournamdar, Z., Salehiniya, H. (2016). Incidence and Mortality and Epidemiology of Breast Cancer in the World. Asian Pacific Journal of Cancer Prevention, 17 (sup3), 43–46. doi: http://doi.org/10.7314/apjcp.2016.17.s3.43
  3. Fedorenko, Z. P., Hulak, L. O., Mykhailovych, Yu. Y., Horokh, Ye. L., Ryzhov, A. Yu., Sumkina, O. V. et. al. (2018). Rak v Ukraini, 2016–2017. Zakhvoriuvanist, smertnist, pokaznyky diialnosti onkolohichnoi sluzhby. Biuleten natsionalnoho kantser-reiestru Ukrainy. Kyiv, 19. Available at: http://www.ncru.inf.ua/publications/BULL_19/index.htm
  4. Zikiryakhodzhayev, A. D., Rasskazova, E. A., Tukmakov, A. Y., Shirokikh, I. M. (2019). Relapses after radical subcutaneous/skin-sparing mastectomy with simultaneous reconstruction in breast cancer. Research’n Practical Medicine Journal, 6 (1), 33–40. doi: http://doi.org/10.17709/2409-2231-2019-6-1-3
  5. Holleczek, B., Stegmaier, C., Radosa, J. C., Solomayer, E.-F., Brenner, H. (2019). Risk of loco-regional recurrence and distant metastases of patients with invasive breast cancer up to ten years after diagnosis – results from a registry-based study from Germany. BMC Cancer, 19 (1). doi: http://doi.org/10.1186/s12885-019-5710-5
  6. Solodkii, V. A., Sherstneva, T. V., Meskikh, E. V., Izmailov, T. R. (2018). The state of the issue of reconstructive plastic surgery for breast cancer in the Russian Federation and in the world. Vestnik Nacionalnogo mediko-khirurgicheskogo Centra im. N. I. Pirogova, 13 (3), 132–137. doi: http://doi.org/10.25881/BPNMSC.2018.78.94.028
  7. Malygin, S. E. (2015). The role of mastectomy in treatment and prophylaxis of breast cancer: beginning, evolution and recent changes. Malignant Tumours, 4, 3–13. doi: http://doi.org/10.18027/2224-5057-2015-4-3-13
  8. Aerts, L., Christiaens, M. R., Enzlin, P., Neven, P., Amant, F. (2014). Sexual functioning in women after mastectomy versus breast conserving therapy for early-stage breast cancer: A prospective controlled study. The Breast, 23 (5), 629–636. doi: http://doi.org/10.1016/j.breast.2014.06.012
  9. Urban, C., Anselmi, K. F., Kuroda, F., Schwartz, J.-C. (2014). Oncoplasty as the Standard of Care in Breast Cancer Surgery. European Oncology & Haematology, 10 (1), 43–47. doi: http://doi.org/10.17925/eoh.2014.10.1.43
  10. Galich, S. P., Pinchuk, V. D. (2011). Rekonstruktivnaia khirurgiia grudi. Kyiv: Kniga-plius, 264.
  11. Sobolevskii, V. A., Ivashkov, V. Iu., Mekhtieva, N. I. G. (2017). Reconstructive and plastic surgery for breast cancer. Prakticheskaia onkologiia, 18 (3), 246–255. Available at: https://practical-oncology.ru/articles/593.pdf
  12. Watts, G. (2016). Umberto Veronesi. The Lancet, 388 (10060), 2600. doi: http://doi.org/10.1016/s0140-6736(16)32230-9
  13. Zikiriakhodzhaev, A., Rasskazova, E. (2015). Organ-sparing surgery for breast cancer. Vrach, 6, 40–42. Available at: http://onco.rusvrach.ru/archive/25877305-2015-06-13.pdf
  14. Maxwell, G. P., Storm-Dickerson, T., Whitworth, P., Rubano, C., Gabriel, A. (2011). Advances in Nipple-Sparing Mastectomy: Oncological Safety and Incision Selection. Aesthetic Surgery Journal, 31 (3), 310–319. doi: http://doi.org/10.1177/1090820x11398111
  15. Kinoshita, S., Kyoda, S., Hirano, A., Akiba, T., Nojima, K., Uchida, K. et. al. (2013). Clinical comparison of four types of skin incisions for skin-sparing mastectomy and immediate breast reconstruction. Surgery Today, 44 (8), 1470–1475. doi: http://doi.org/10.1007/s00595-013-0722-2
  16. Lai, H.-W., Wu, H.-S., Chuang, K.-L., Chen, D.-R., Chang, T.-W., Kuo, S.-J. et. al. (2014). Endoscopy-assisted total mastectomy followed by immediate pedicled transverse rectus abdominis musculocutaneous (TRAM) flap reconstruction: preliminary results of 48 patients. Surgical Innovation, 22 (4), 382–389. doi: http://doi.org/10.1177/1553350614546003
  17. Lai, H.-W., Chen, S.-T., Chen, D.-R., Chen, S.-L., Chang, T.-W., Kuo, S.-J. et. al. (2016). Current Trends in and Indications for Endoscopy-Assisted Breast Surgery for Breast Cancer: Results from a Six-Year Study Conducted by the Taiwan Endoscopic Breast Surgery Cooperative Group. PLOS ONE, 11(3), e0150310. doi:10.1371/journal.pone.0150310
  18. Tukenmez, M., Ozden, B. C., Agcaoglu, O., Kecer, M., Ozmen, V., Muslumanoglu, M., Igci, A. (2014). Videoendoscopic Single-Port Nipple-Sparing Mastectomy and Immediate Reconstruction. Journal of Laparoendoscopic & Advanced Surgical Techniques, 24 (2), 77–82. doi: http://doi.org/10.1089/lap.2013.0172
  19. Bit-Sava, E. M., Egorenkov, V. V., Damenia, A. O., Melnikova, O. A., Akhmedov, R. M., Monogarova, M. A. et. al. (2017). New approaches in breast cancer surgery. Practical Oncology, 18 (3), 232–245. doi: http://doi.org/10.31917/1803232
  20. Ermoshchenkova, M. V., Chissov, V. I., Usov, A. V., Sukhotko, A. S., Tukmakov, A. Y., Baichorov, E. A., Zikiryahodjaev, A. D. (2017). Biological and synthetic mesh use in reconstructive surgery in patients with breast cancer. Research’n Practical Medicine Journal, 4 (1), 23–32. doi: http://doi.org/10.17709/2409-2231-2017-4-1-3
  21. Franceschini, G., Martin, S. A., Di Leon, A., Magno, A., Moschella, F., Accetta, C., Masetti, R. (2015). New trends in breast cancer surgery: a therapeutic approach increasingly efficacy and respectful of the patient. Giornale di Chirurgia – Journal of Surgery, 36 (4), 145–152. doi: http://doi.org/10.11138/gchir/2015.36.4.145
  22. Hernanz, F., Sánchez, S., Cerdeira, M. P., Figuero, C. R. (2011). Long-term results of breast conservation and immediate volume replacement with myocutaneous latissimus dorsi flap. World Journal of Surgical Oncology, 9 (1). doi: http://doi.org/10.1186/1477-7819-9-159
  23. Wang, X.-L., Liu, L.-B., Song, F.-M., Wang, Q.-Y. (2014). Meta-analysis of the Safety and Factors Contributing to Complications of MS-TRAM, DIEP, and SIEA Flaps for Breast Reconstruction. Aesthetic Plastic Surgery, 38 (4), 681–691. doi: http://doi.org/10.1007/s00266-014-0333-3
  24. Simonacci, F., Bertozzi, N., Grieco, M. P., Grignaffini, E., Raposio, E. (2016). Autologous fat transplantation for breast reconstruction: A literature review. Annals of Medicine and Surgery, 12, 94–100. doi: http://doi.org/10.1016/j.amsu.2016.11.012
  25. Van Turnhout, A. A., Fuchs, S., Lisabeth-Broné, K., Vriens-Nieuwenhuis, E. J. C., van der Sluis, W. B. (2017). Surgical Outcome and Cosmetic Results of Autologous Fat Grafting After Breast Conserving Surgery and Radiotherapy for Breast Cancer: A Retrospective Cohort Study of 222 Fat Grafting Sessions in 109 Patients. Aesthetic Plastic Surgery, 41 (6), 1334–1341. doi: http://doi.org/10.1007/s00266-017-0946-4
  26. Zikiryakhodzhaev, A. D., Efanov, V. V., Usov, F. N., Ismailova, M. M. (2015). Complications of delayed reconstructive and plastic surgery after radical mastectomy. Tumors of Female Reproductive System, 11 (2), 31–34. doi: http://doi.org/10.17650/1994-4098-2015-11-2-31-34
  27. Maxwell, G. P., Gabriel, M. (2017). Breast implant design. Gland Surgery, 6 (2), 148–153. doi: http://doi.org/10.21037/gs.2016.11.09
  28. Zikiryakhodzhaev, A. D., Shirokikh, I. M., Ablitsova, N. V., Ermoshchenkova, M. V., Kharchenko, N. V., Saribekyan, E. K. et. al. (2018). Biological and synthetic materials in reconstructive surgery for breast cancer treatment (literature review). Tumors of Female Reproductive System, 14 (1), 28–37. doi: http://doi.org/10.17650/1994-4098-2018-14-1-28-37
  29. Dragun, A. E., Huang, B., Tucker, T. C., Spanos, W. J. (2012). Increasing Mastectomy Rates Among all Age Groups for Early Stage Breast Cancer: A 10-Year Study of Surgical Choice. The Breast Journal, 18 (4), 318–325. doi: http://doi.org/10.1111/j.1524-4741.2012.01245.x
  30. Ho, A. L., Bovill, E. S., Macadam, S. A., Tyldesley, S., Giang, J., Lennox, P. A. (2014). Postmastectomy Radiation Therapy after Immediate Two-Stage Tissue Expander/Implant Breast Reconstruction. Plastic and Reconstructive Surgery, 134 (1), 1e–10e. doi: http://doi.org/10.1097/prs.0000000000000292
  31. Khailenko, D. V., Egorov, Iu. S., Portnoi, S. M., Khailenko, V. A. (2016) Primary reconstructive plastic surgery in nodular form of III stage breast cancer. Rossiiskii onkologicheskii zhurnal, 21 (4), 175–178.
  32. Cordeiro, P. G., Albornoz, C. R., McCormick, B., Hu, Q., Van Zee, K. (2014). The impact of postmastectomy radiotherapy on two-stage implant breast reconstruction: an analysis of long-term surgical outcomes, aesthetic results, and satisfaction over 13 years. Plastic and Reconstructive Surgery, 134 (4), 588–595. doi: http://doi.org/10.1097/prs.0000000000000523
  33. Nahabedian, M. Y., Jacobson, S. R. (2019). Two-stage prepectoral breast reconstruction. Gland Surgery, 8 (1), 43–52. doi: http://doi.org/10.21037/gs.2018.09.04
  34. Casella, D., Di Taranto, G., Marcasciano, M., Lo Torto, F., Barellini, L., Sordi, S. et. al. (2019). Subcutaneous expanders and synthetic mesh for breast reconstruction: Long-term and patient-reported BREAST-Q outcomes of a single-center prospective study. Journal of Plastic, Reconstructive & Aesthetic Surgery, 72 (5), 805–812. doi: http://doi.org/10.1016/j.bjps.2018.12.018
  35. Hon, H. H., Mubang, R. N., Wernick, B. D., Freedman, S. F., Stoltzfus, J. C., Miele, L. F. et. al. (2017). Acellular dermal matrix versus inferior deepithelialized flap breast reconstruction: equivalent outcomes, with increased cost. Plastic and Reconstructive Surgery – Global Open, 5 (6), e1382. doi: http://doi.org/10.1097/gox.0000000000001382
  36. Sorkin, M., Qi, J., Kim, H. M., Hamill, J. B., Kozlow, J. H., Pusic, A. L., Wilkins, E. G. (2017). Acellular dermal matrix in immediate expander/implant breast reconstruction: a multicenter assessment of risks and benefits. Plastic and Reconstructive Surgery, 140 (6), 1091–1100. doi: http://doi.org/10.1097/prs.0000000000003842
  37. Zikiryahodzhaev, A. D., Rasskazova, E. A. (2018). Two-stage delayed reconstruction in patients with breast cancer after mastectomy. Malignant Tumours, 8 (2), 43–49. doi: http://doi.org/10.18027/2224-5057-2018-8-2-43-49
  38. Hvilsom, G. B., Hölmich, L. R., Frederiksen, K., Steding-Jessen, M., Friis, S., Dalton, S. O. (2010). Socioeconomic position and breast reconstruction in Danish women. Acta Oncologica, 50 (2), 265–273. doi: http://doi.org/10.3109/0284186x.2010.529823
  39. Thiruchelvam, P. T. R., McNeill, F., Jallali, N., Harris, P., Hogben, K. (2013). Post-mastectomy breast reconstruction. BMJ, 347 (2), f5903–f5903. doi: http://doi.org/10.1136/bmj.f5903
  40. Park, E. H., Min, S. Y., Kim, Z., Yoon, C. S., Jung, K.-W. et. al. (2017). Basic Facts of Breast Cancer in Korea in 2014: The 10-Year Overall Survival Progress. Journal of Breast Cancer, 20 (1), 1. doi: http://doi.org/10.4048/jbc.2017.20.1.1
  41. Nguyen, T. T., Hoskin, T. L., Habermann, E. B., Cheville, A. L., Boughey, J. C. (2017). Breast Cancer-Related Lymphedema Risk is Related to Multidisciplinary Treatment and Not Surgery Alone: Results from a Large Cohort Study. Annals of Surgical Oncology, 24 (10), 2972–2980. doi: http://doi.org/10.1245/s10434-017-5960-x
  42. Madsen, R. J., Esmonde, N. O., Ramsey, K. L., Hansen, J. E. (2016). Axillary Lymph Node Dissection Is a Risk Factor for Major Complications After Immediate Breast Reconstruction. Annals of Plastic Surgery, 77 (5), 513–516. doi: http://doi.org/10.1097/sap.0000000000000653
  43. Marinescu, S. A., Bejinariu, C. G., Şapte, E., Marinaş, M. C., Giuglea, C. (2019). Complications related to breast reconstruction after mastectomy using multiple surgical techniques – a national and international comparative analysis. Romanian Journal of Morphology and Embryology, 60 (1), 87–93.
  44. Gambardella, C., Clarizia, G., Patrone, R., Offi, C., Mauriello, C., Romano, R. et. al. (2019). Advanced hemostasis in axillary lymph node dissection for locally advanced breast cancer: new technology devices compared in the prevention of seroma formation. BMC Surgery, 18 (S1). doi: http://doi.org/10.1186/s12893-018-0454-8
  45. Vinnyk, Y. O., Vlasenko, V. G., Baranova, A. V. (2019). Prophylaxis of complications after radical operations in patients, suffering a mammary gland cancer. Klinicheskaia Khirurgiia, 86 (11-12), 46–50. doi: http://doi.org/10.26779/2522-1396.2019.11-12.46

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Published

2020-07-31

How to Cite

Tamm, T., Vinnуk Y., Starikov, V., Prokopyuk, O., Oleynik, G., & Vlasenko, V. (2020). Organ-saving and reconstructive plastic surgery of breast cancer. ScienceRise: Medical Science, (4 (37), 53–57. https://doi.org/10.15587/2519-4798.2020.209149

Issue

No. 4 (37) (2020)

Section

Medical Science

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Copyright (c) 2020 Tamara Tamm, Yuri Vinnуk, Volodimir Starikov, Oleksandra Prokopyuk, Grіgory Oleynik, Vadym Vlasenko

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