Current approaches to the therapy of vulvovaginites taking into account antibiotic resistance to the infectious agents

Authors

  • Глеб Михайлович Бондаренко SE «Institute of Dermatology and Venerology of National Academy of Medical Sciences of Ukraine» 7/9 Chernyshevkay str., Kharkov, Ukraine, 61057, Ukraine https://orcid.org/0000-0002-0799-797X
  • Светлана Карьягдыевна Джораева SE «Institute of Dermatology and Venerology of National Academy of Medical Sciences of Ukraine» Chernyshevkay str., 7/9, Kharkov, Ukraine, 61057, Ukraine https://orcid.org/0000-0003-2486-5474
  • Анна Константиновна Кондакова Sciences of Ukraine» Chernyshevkay str., 7/9, Kharkov, Ukraine, 61057, Ukraine https://orcid.org/0000-0002-7739-1922
  • Ольга Анатольевна Лященко National medical university of Ukraine Health Ministry Nauki ave., 4, Kharkov, Ukraine, 61022, Ukraine
  • Юлия Валерьевна Щербакова SE «Institute of Dermatology and Venerology of National Academy of Medical Sciences of Ukraine» Chernyshevkay str., 7/9, Kharkov, Ukraine, 61057, Ukraine https://orcid.org/0000-0002-3682-7451
  • Наталия Владимировна Соболь SE «Institute of Dermatology and Venerology of National Academy of Medical Sciences of Ukraine» Chernyshevkay str., 7/9, Kharkov, Ukraine, 61057, Ukraine https://orcid.org/0000-0002-3622-0174

DOI:

https://doi.org/10.15587/2519-4798.2016.77255

Keywords:

nonspecific vulvovaginitis, microbiocenosis, conventionally pathogenic microflora, sensitivity to antibacterial preparations

Abstract

Aim of research: the study of qualitative composition and parameters of sensitivity/resistance to antibiotics of the different groups of biota of the low parts of genital tract in patients with nonspecific vulvovaginites.

Methods of research: 242 women 18-47 years old underwent clinical-laboratory examination on the base of clinic and department of sexually transmitted infections SI “Institute of dermatology and venereology, NAMS of Ukraine”. They were divided in two groups: 1st group – 205 (84,7 %) patients with clinical and laboratory signs of vulvovaginitis; 2th group (control one) -– 37 (15,3 %) clinically healthy women. All patients, included in the research, underwent the complex of laboratory examinations according to the regulative documents of HM of Ukraine.

Results of research: The composition of vaginal microbiocenosis in patients with vulgovaginites, caused by conventionally pathogenic microorganisms was characterized with the prevalence of aerobic representatives of Enterobacteriaceae and Staphylococcaceae families that formed association both between themselves and with representatives of the other taxonomic groups. The therapy of vulvovaginites, caused by aerobic conventionally pathogenic microorganisms, must be realized individually, taking into account the results of determination of sensitivity of the aerobic microflora. At impossibility of cultural study with determination of sensitivity of separated microorganisms to antibacterial remedies, the preparations of choice in the treatment of vulvovaginites, caused with conventionally pathogenic microorganisms can be quinolones, lincosamides, nitrofurans and ceftriaxone that the higher sensitivity of conventionally pathogenic microorganisms was observed to

Author Biographies

Глеб Михайлович Бондаренко, SE «Institute of Dermatology and Venerology of National Academy of Medical Sciences of Ukraine» 7/9 Chernyshevkay str., Kharkov, Ukraine, 61057

Doctor of medicine, professor, head of department

Department of sexually transmitted diseases

Светлана Карьягдыевна Джораева, SE «Institute of Dermatology and Venerology of National Academy of Medical Sciences of Ukraine» Chernyshevkay str., 7/9, Kharkov, Ukraine, 61057

Candidate of Medical Sciences, head of laboratory

Microbiological laboratory

Анна Константиновна Кондакова, Sciences of Ukraine» Chernyshevkay str., 7/9, Kharkov, Ukraine, 61057

Candidate of Biological Sciences, deputy director for science 

Ольга Анатольевна Лященко, National medical university of Ukraine Health Ministry Nauki ave., 4, Kharkov, Ukraine, 61022

Candidate of Medical Sciences, associate professor

Obstetrics and gynecology cathedra № 2

Юлия Валерьевна Щербакова, SE «Institute of Dermatology and Venerology of National Academy of Medical Sciences of Ukraine» Chernyshevkay str., 7/9, Kharkov, Ukraine, 61057

Candidate of Medical Sciences, Senior Research Fellow

Department of study of the effect of the HIV epidemic on the problem of sexually transmitted infections 

Наталия Владимировна Соболь, SE «Institute of Dermatology and Venerology of National Academy of Medical Sciences of Ukraine» Chernyshevkay str., 7/9, Kharkov, Ukraine, 61057

Вoctor-bacteriologist

Сlinical laboratory

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Published

2016-09-30

How to Cite

Бондаренко, Г. М., Джораева, С. К., Кондакова, А. К., Лященко, О. А., Щербакова, Ю. В., & Соболь, Н. В. (2016). Current approaches to the therapy of vulvovaginites taking into account antibiotic resistance to the infectious agents. ScienceRise: Medical Science, (9 (5), 19–25. https://doi.org/10.15587/2519-4798.2016.77255

Issue

No. 9 (5) (2016)

Section

Medical Science

License

Copyright (c) 2016 Глеб Михайлович Бондаренко, Светлана Карьягдыевна Джораева, Анна Константиновна Кондакова, Ольга Анатольевна Лященко, Юлия Валерьевна Щербакова, Наталия Владимировна Соболь

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