Roman Lesyk

Danylo Halytsky Lviv National Medical University, Ukraine
PhD, DSc, professor, Head of Department of Pharmaceutical, Organic and Bioorganic Chemistry

Scopus profile: link
GoogleScholar profile: link
ID ORCID: http://orcid.org/0000-0002-3322-0080

Professional (scientific) interests:
medicinal and organic chemistry.

Selected Publications:

  1. Holota, S., Komykhov, S., Sysak, S., Gzella, A., Cherkas, A., Lesyk, R. (2021). Synthesis, Characterization and In Vitro Evaluation of Novel 5-Ene-thiazolo[3,2-b][1,2,4]triazole-6(5H)-ones as Possible Anticancer Agents. Molecules, 26 (4), 1162. doi: http://doi.org/10.3390/molecules26041162 

  2. Pyrih, A., Jaskolski, M., Gzella, A. K., Lesyk, R. (2021). Synthesis, structure and evaluation of anticancer activity of 4-amino-1,3-thiazolinone/pyrazoline hybrids. Journal of Molecular Structure, 1224, 129059. doi: http://doi.org/10.1016/j.molstruc.2020.129059 

  3. Zelisko, N., Karpenko, O., Muzychenko, V., Gzella, A., Lesyk, R. (2021). Citraconic acid and its anhydride-based hetero-Diels–Alder reactions in the synthesis of new thiopyrano[2,3-d][1,3]thiazole derivatives. Synthetic Communications, 1–7. doi: http://doi.org/10.1080/00397911.2020.1867868 

  4. Konechnyi, Y., Hrushka, O., Pryzyhley, H., Konechna, R., Lozynskyi, A., Korniychuk, O., Lesyk, R. (2021). Cell immunity of laboratory animals under the influence of 5-indolylmethylene rhodanine-3-carboxylic/sulphonic acid derivative. ScienceRise: Pharmaceutical Science, 1 (29), 76–81. doi: http://doi.org/10.15587/2519-4852.2021.224328 

  5. Holota, S. M., Nektegayev, I. O., Soronovych, I. I., Chubuchna, I. I., Kolishetska, M. A., Lesyk, R. B. et. al. (2021). The novel pyrazolin-5-one bearing thiazolidin-4-ones: synthesis, characterization and biological evaluation. Biopolymers and Cell, 37 (1), 46–61. doi: http://doi.org/10.7124/bc.000a4b 

  6. Schadich, E., Kryshchyshyn-Dylevych, A., Holota, S., Polishchuk, P., Džubak, P., Lesyk, R. et. al. (2020). Assessing different thiazolidine and thiazole based compounds as antileishmanial scaffolds. Bioorganic & Medicinal Chemistry Letters, 30 (23), 127616. doi: http://doi.org/10.1016/j.bmcl.2020.127616 

  7. Syngaevsky, V., Karkhut, A., Polovkovych, S., Gzella, A., Lesyk, R., Novikov, V. (2020). Study of 1,3-dipolar cycloaddition of amino-acid azomethines and Juglone. Synthetic Communications, 50 (20), 3165–3173. doi: http://doi.org/10.1080/00397911.2020.1795880