Roman Lesyk

Danylo Halytsky Lviv National Medical University, Ukraine
PhD, DSc, professor, Head of Department of Pharmaceutical, Organic and Bioorganic Chemistry

Scopus profile: link
Researcher ID: A-3395-2015
GoogleScholar profile: link
ID ORCID: http://orcid.org/0000-0002-3322-0080

Professional (scientific) interests: medicinal and organic chemistry.

Selected Publications:

  1. Roszczenko, P., Szewczyk-Roszczenko, O. K., Gornowicz, A., Czarnomysy, R., Lozynskyi, A., Bielawski, K., Lesyk, R., Bielawska, A. (2024). Trastuzumab Potentiates Antitumor Activity of Thiopyrano[2,3-d]Thiazole Derivative in AGS Gastric Cancer Cells. Molecules, 29 (21), 5117. https://doi.org/10.3390/molecules29215117

  2. Davydov, E., Hoidyk, M., Shtrygol’, S., Karkhut, A., Polovkovych, S., Klyuchivska, O., Karpenko, O., Lesyk, R., Holota, S. (2024). Evaluation of thiopyrano[2,3‐d]thiazole derivatives as potential anticonvulsant agents. Archiv Der Pharmazie, 357 (10). https://doi.org/10.1002/ardp.202400357

  3. Kaleniuk, E., Holota, S., Skóra, B., Khylyuk, D., Tabęcka-Łonczyńska, A., Lesyk, R., Szychowski, K. A. (2024). Anticancer Properties of Peroxisome Proliferator-Activated Receptor Gamma (PPARγ) Potential Agonists 4-Thiazolidinone-Pyrazoline Hybrids Les-4368 and Les-4370 in Colorectal Adenocarcinoma Cells In Vitro. Applied Sciences, 14 (17), 7692. https://doi.org/10.3390/app14177692

  4. Cherniienko, A., Lesyk, R., Zaprutko, L., Pawełczyk, A. (2024). IR-EcoSpectra: Exploring sustainable ex situ and in situ FTIR applications for green chemical and pharmaceutical analysis. Journal of Pharmaceutical Analysis, 14 (9), 100951. https://doi.org/10.1016/j.jpha.2024.02.005

  5. Zelisko, N., Lesyk, R., Stoika, R. (2024). Structure, unique biological properties, and mechanisms of action of transforming growth factor β. Bioorganic Chemistry, 150, 107611. https://doi.org/10.1016/j.bioorg.2024.107611

  6. Finiuk, N., Kozak, Y., Gornowicz, A., Czarnomysy, R., Tynecka, M., Holota, S., Moniuszko, M., Stoika, R., Lesyk, R., Bielawski, K., Bielawska, A. (2024). The Proapoptotic Action of Pyrrolidinedione–Thiazolidinone Hybrids towards Human Breast Carcinoma Cells Does Not Depend on Their Genotype. Cancers, 16 (16), 2924. https://doi.org/10.3390/cancers16162924

  7. Szlachcikowska, D., Tabęcka-Łonczyńska, A., Holota, S., Roman, O., Shepeta, Y., Lesyk, R., Szychowski, K. A. (2024). Role of Ciminalum-4-thiazolidinone Hybrids in Molecular NF-κB Dependent Pathways. International Journal of Molecular Sciences, 25 (13), 7329. https://doi.org/10.3390/ijms25137329