Topographic peculiarities of localization of fungi of the genus Candida isolated from sub-biotopes of the oral cavity of practically healthy persons

Authors

DOI:

https://doi.org/10.15587/2519-8025.2018.153466

Keywords:

Candida fungi, Candida albicans, candidiasis, candidiasis carriage, topographic features

Abstract

Purpose. Establishment of topographic features of the localization of Candida fungi isolated from the sub-biotopes of the oral cavity of practically healthy persons without clinical signs of candidiasis.

Methods. The following methods are used: microscopic; mycological - cultural studies of biomaterial strains from practically healthy persons; biochemical – for the purpose of species identification of Candida fungi; statistical methods.

Research results. During the experiment, 292 sub-biotopes of the oral cavity are investigated. The material is taken from the mucous membrane of the cheek, the corner of the mouth, the mucous membrane of the surface of the tongue and the palate. According to the results of the conducted research, the level of candidiasis carriage on the oral mucosa in practically healthy individuals without clinical signs of candidiasis is 56.4 %. Candidiasis carrier level on the dorsal surface of the tongue is 38.46 %, the retromolar part of the cheek is 30.77 %, the angle of the mouth is 18.8 %, and the palate is 11.97 %. Among all isolated strains, prevails in all 4 sub-biotopes of C. albicans – 76.07 %. It is noted that in 8 people in the biotope of the oral cavity, but in different sub-biotopes, two species of the genus Candida, C. krusei and C. albicans, are isolated, and in 7 people, C. glabrata and C. albicans. In addition, the coexistence of two candida types is found in 5 sub-biotopes.

Conclusions

1. The level of candidiasis carriage in the oral biotope among practically healthy individuals without clinical signs of candidiasis is 56.4%. The level of candidiasis carriage of the oral biotope in practically healthy persons without clinical manifestations of candidiasis has increased significantly over the past 5 years.

2. Among the identified strains, Candida albicans prevails – 76.07 %.

3. The highest rate of colonization compared with other sub-biotopes is observed on the dorsal surface of the tongue – 38.46%. During the study, the coexistence of two Candida types is revealed. In 8 people in the biotope of the oral cavity, but in different sub-biotopes, two species of the genus Candida, C. krusei and C. albicans, are isolated, and in 7 people, C. glabrata and C. albicans, which confirms the importance of establishing topographic features of the fungi localization in the oral cavity for the rationality of using antimycotics if necessary

Author Biography

Nadiia Osypchuk, Bogomolets National Medical University Tarasа Shevchenkа blvd., 13, Kyiv, Ukraine, 01601

Assistant

Department of Microbiology, Virology and Immunology

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Published

2018-12-31

How to Cite

Osypchuk, N. (2018). Topographic peculiarities of localization of fungi of the genus Candida isolated from sub-biotopes of the oral cavity of practically healthy persons. ScienceRise: Biological Science, (6 (15), 14–18. https://doi.org/10.15587/2519-8025.2018.153466

Issue

Section

Biological Sciences