Pathophysiology characteristics of the experimental model of obesity in female rats induced neonatal administration of monosodium glutamate

Authors

  • Вікторія Василівна Конопельнюк ESC "Institute of Biology and Medicine" Taras Shevchenko National University of Kyiv Volodymyrska str., 64/13, Kyiv, Ukraine, 01601, Ukraine
  • Ірина Юріївна Прибитько Educational-Scientific Center "Institute of Biology" Taras Shevchenko National University of Kyiv Volodymyrska str., 64/13, Kyiv, Ukraine, 01601, Ukraine
  • Олена Іванівна Цирюк Educational-Scientific Center "Institute of Biology" Taras Shevchenko National University of Kyiv Volodymyrska str., 64/13, Kyiv, Ukraine, 01601, Ukraine
  • Тетяна Михайлівна Фалалєєва Educational-Scientific Center "Institute of Biology" Taras Shevchenko National University of Kyiv Volodymyrska str., 64/13, Kyiv, Ukraine, 01601, Ukraine

DOI:

https://doi.org/10.15587/2519-8025.2016.83570

Keywords:

monosodium glutamate, obesity, rats, body mass index, glucose-tolerant test

Abstract

It was shown that in rats of 4 months age, the injection of monosodium glutamate elicited visceral obesity. To confirm the symptoms of obesity with type 2 diabetes, we had a glucose-tolerant test. In animals with obesityб glucose levels in 2 hours after a glucose was 10,65±2,215mmol / L, that was noted glucose intolerance

Author Biographies

Вікторія Василівна Конопельнюк, ESC "Institute of Biology and Medicine" Taras Shevchenko National University of Kyiv Volodymyrska str., 64/13, Kyiv, Ukraine, 01601

PhD, senior researcher

SRL "Physico-Chemical Biology"

Department of Experimental Biology

Ірина Юріївна Прибитько, Educational-Scientific Center "Institute of Biology" Taras Shevchenko National University of Kyiv Volodymyrska str., 64/13, Kyiv, Ukraine, 01601

PhD, Research Associate

Department of pharmacology and experimental pathology

Олена Іванівна Цирюк, Educational-Scientific Center "Institute of Biology" Taras Shevchenko National University of Kyiv Volodymyrska str., 64/13, Kyiv, Ukraine, 01601

PhD, Senior Research

Тетяна Михайлівна Фалалєєва, Educational-Scientific Center "Institute of Biology" Taras Shevchenko National University of Kyiv Volodymyrska str., 64/13, Kyiv, Ukraine, 01601

Doctor of Biological Sciences, Senior researcher, Head of department

Department of fundamental medicine

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Published

2016-11-18

How to Cite

Конопельнюк, В. В., Прибитько, І. Ю., Цирюк, О. І., & Фалалєєва, Т. М. (2016). Pathophysiology characteristics of the experimental model of obesity in female rats induced neonatal administration of monosodium glutamate. ScienceRise: Biological Science, (3 (3), 14–18. https://doi.org/10.15587/2519-8025.2016.83570

Issue

Section

Biological Sciences