Evaluation of the toxic effect of nandrolone and albendazole on fish according to the morphological parameters of blood

Authors

DOI:

https://doi.org/10.15587/2519-8025.2018.123900

Keywords:

carp, blood morphology, hemoglobin, erythrocytes, SOE, leukogram, xenobiotics, nandrolone, albendazole

Abstract

There were studied the morphological parameters of blood of carps at adding the hormone nandrolone and anthelmintic albendazole in water. Nandrolone even in the unessential concentration (0,1 mg/dm3 of water) increases the content of hemoglobin, number of erythrocytes and SOE value, but decreases the number of eosinophils, segment-kernel neutrophils and doesn’t influence the number of leucocytes, lymphocytes and monocytes in blood of two year aged carps. At the nandrolone concentration in water of an aquarium 0,5 mg/dm3 and 1,0 mg/dm3, that fishes of the second and thirds group were kept in, the influence of the hormone on the morphological parameters of blood increased that is testified by the change of the content of hemoglobin, SOE value, number of erythrocytes, leucocytes, eosinophils and monocytes at the stable value of lymphocytes.

The anthelmintic albendazole, added in water in the concentration 1,0 mg/dm3 decreased the content of hemoglobin and number of erythrocytes and didn’t influence the other morphological parameters of fish blood. The increase of the abendazole concentration in aquarium water up to 0,5 and 1,0 mg/dm3 essentially influenced morphological parameters of fish blood, decreasing the content of hemoglobin, number of erythrocytes, leucocytes, eosinophils, neutrophils, at the same time increasing the number of lymphocytes and SOE value.

The influence of the anthelmintic albendazole on the morphological parameters of carp blood turned out to be more expressed that one of the nandrolone hormone

Author Biographies

Mykola Zakharenko, National University of Life and Environmental Sciences of Ukraine Heroiv Oborony str., 15, Kyiv, Ukraine, 03041

Doctor of Biological Sciences, Professor

Department of hygiene and sanitation named after A. K. Skorokhodko

Inna Kurbatova, National University of Life and Environmental Sciences of Ukraine Heroiv Oborony str., 15, Kyiv, Ukraine, 03041

PhD, Associate Professor

Department of Animal Biology

Liudmyla Chepil, National University of Life and Environmental Sciences of Ukraine Heroiv Oborony str., 15, Kyiv, Ukraine, 03041

PhD, Associate Professor

Department of Animal Biology

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Published

2018-02-19

How to Cite

Zakharenko, M., Kurbatova, I., & Chepil, L. (2018). Evaluation of the toxic effect of nandrolone and albendazole on fish according to the morphological parameters of blood. ScienceRise: Biological Science, (1 (10), 4–8. https://doi.org/10.15587/2519-8025.2018.123900

Issue

No. 1 (10) (2018)

Section

Biological Sciences

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Copyright (c) 2018 Mykola Zakharenko, Inna Kurbatova, Liudmyla Chepil

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